8-azaguanine-7444 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the 8-azaguanine-7444 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ADAM22 ADAM metallopeptidase domain 22
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKR1C2 aldo-keto reductase family 1, member C2
ALS2CL ALS2 C-terminal like
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BGN biglycan
C21ORF2 chromosome 21 open reading frame 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAPG capping protein (actin filament), gelsolin-like
CCDC40 coiled-coil domain containing 40
CD53 CD53 molecule
CDHR2 cadherin-related family member 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLMN calmin (calponin-like, transmembrane)
COL4A1 collagen, type IV, alpha 1
CPNE7 copine VII
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CROCC ciliary rootlet coiled-coil, rootletin
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DBP D site of albumin promoter (albumin D-box) binding protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNM1 dynamin 1
ELP6 elongator acetyltransferase complex subunit 6
FASTKD2 FAST kinase domains 2
GJA9 gap junction protein, alpha 9, 59kDa
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
GPR137 G protein-coupled receptor 137
GPR4 G protein-coupled receptor 4
GRTP1 growth hormone regulated TBC protein 1
HGD homogentisate 1,2-dioxygenase
HIST1H3F histone cluster 1, H3f
HYI hydroxypyruvate isomerase (putative)
IL1A interleukin 1, alpha
IPO9 importin 9
IQCK IQ motif containing K
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDM8 lysine (K)-specific demethylase 8
KPTN kaptin (actin binding protein)
LPIN1 lipin 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K6 mitogen-activated protein kinase kinase 6
MAP4 microtubule-associated protein 4
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTSS1L metastasis suppressor 1-like
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NMT2 N-myristoyltransferase 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPRL1 opiate receptor-like 1
PDCD6 programmed cell death 6
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4C phosphodiesterase 4C, cAMP-specific
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POM121L2 POM121 transmembrane nucleoporin-like 2
PORCN porcupine homolog (Drosophila)
PRKG2 protein kinase, cGMP-dependent, type II
PTCRA pre T-cell antigen receptor alpha
RAB3A RAB3A, member RAS oncogene family
RND2 Rho family GTPase 2
RUNX1 runt-related transcription factor 1
S100A9 S100 calcium binding protein A9
SMAD1 SMAD family member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SPN sialophorin
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STAT5B signal transducer and activator of transcription 5B
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBX6 T-box 6
TCP10 t-complex 10
TCP10L t-complex 10-like
TCP11L1 t-complex 11, testis-specific-like 1
TIMELESS timeless circadian clock
TMPRSS6 transmembrane protease, serine 6
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRIM29 tripartite motif containing 29
TTC38 tetratricopeptide repeat domain 38
USF2 upstream transcription factor 2, c-fos interacting
USP27X ubiquitin specific peptidase 27, X-linked
VN1R1 vomeronasal 1 receptor 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WNT2B wingless-type MMTV integration site family, member 2B
XDH xanthine dehydrogenase
ZNF428 zinc finger protein 428
ZNF516 zinc finger protein 516
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
AMDHD2 amidohydrolase domain containing 2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD28 ankyrin repeat domain 28
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ASB9 ankyrin repeat and SOCS box containing 9
ATAD5 ATPase family, AAA domain containing 5
BCCIP BRCA2 and CDKN1A interacting protein
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BIK BCL2-interacting killer (apoptosis-inducing)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF68 chromosome 11 open reading frame 68
C1ORF115 chromosome 1 open reading frame 115
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CDK9 cyclin-dependent kinase 9
DDIT3 DNA-damage-inducible transcript 3
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DTWD1 DTW domain containing 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EXOC5 exocyst complex component 5
FAM117A family with sequence similarity 117, member A
FAM63A family with sequence similarity 63, member A
FCHSD2 FCH and double SH3 domains 2
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALK1 galactokinase 1
GTF2I general transcription factor IIi
HCFC2 host cell factor C2
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFT81 intraflagellar transport 81
INF2 inverted formin, FH2 and WH2 domain containing
IRF2 interferon regulatory factor 2
IRX4 iroquois homeobox 4
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KATNBL1 katanin p80 subunit B-like 1
KIZ kizuna centrosomal protein
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MANEA mannosidase, endo-alpha
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MTMR11 myotubularin related protein 11
NAP1L4 nucleosome assembly protein 1-like 4
NARFL nuclear prelamin A recognition factor-like
NCAM2 neural cell adhesion molecule 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NOTCH1 notch 1
NT5C 5', 3'-nucleotidase, cytosolic
NUPL2 nucleoporin like 2
OSGEP O-sialoglycoprotein endopeptidase
PAQR3 progestin and adipoQ receptor family member III
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POMZP3 POM121 and ZP3 fusion
PPL periplakin
PRMT7 protein arginine methyltransferase 7
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PYCRL pyrroline-5-carboxylate reductase-like
RAB17 RAB17, member RAS oncogene family
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RCL1 RNA terminal phosphate cyclase-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SAV1 salvador family WW domain containing protein 1
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A40 solute carrier family 25, member 40
SLC35F5 solute carrier family 35, member F5
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SNIP1 Smad nuclear interacting protein 1
SPIDR scaffolding protein involved in DNA repair
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D31 TBC1 domain family, member 31
TRAPPC13 trafficking protein particle complex 13
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WDR44 WD repeat domain 44
WDR60 WD repeat domain 60
WDR7 WD repeat domain 7
XAB2 XPA binding protein 2
XPC xeroderma pigmentosum, complementation group C
ZNF273 zinc finger protein 273
ZNF480 zinc finger protein 480