786O Gene Set

Dataset CCLE Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human renal cell adenocarcinoma cell line, established from a 58 years old caucasian male. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003781)
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90 genes mutated in the 786O cell line from the CCLE Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ADAM17 ADAM metallopeptidase domain 17
ADAM28 ADAM metallopeptidase domain 28
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADCK3 aarF domain containing kinase 3
ADGRB1 adhesion G protein-coupled receptor B1
ADGRG4 adhesion G protein-coupled receptor G4
AKAP12 A kinase (PRKA) anchor protein 12
AKAP9 A kinase (PRKA) anchor protein 9
ALPK2 alpha-kinase 2
ATM ATM serine/threonine kinase
CDK11B cyclin-dependent kinase 11B
CHD1 chromodomain helicase DNA binding protein 1
CIT citron rho-interacting serine/threonine kinase
CLTCL1 clathrin, heavy chain-like 1
CNTN1 contactin 1
CNTN6 contactin 6
DACH1 dachshund family transcription factor 1
EDN1 endothelin 1
EPHB2 EPH receptor B2
EPS15 epidermal growth factor receptor pathway substrate 15
ETV1 ets variant 1
FGFR1OP FGFR1 oncogene partner
FGFR3 fibroblast growth factor receptor 3
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FN1 fibronectin 1
FZD1 frizzled class receptor 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GUCY2C guanylate cyclase 2C
HNF1A HNF1 homeobox A
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IL1A interleukin 1, alpha
ILK integrin-linked kinase
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KMT2C lysine (K)-specific methyltransferase 2C
KSR1 kinase suppressor of ras 1
LRP2 low density lipoprotein receptor-related protein 2
MAML3 mastermind-like 3 (Drosophila)
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST4 microtubule associated serine/threonine kinase family member 4
MCM3AP minichromosome maintenance complex component 3 associated protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MGA MGA, MAX dimerization protein
MLH1 mutL homolog 1
MSH3 mutS homolog 3
MYB v-myb avian myeloblastosis viral oncogene homolog
MYO3B myosin IIIB
NCAM1 neural cell adhesion molecule 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOTCH3 notch 3
NPR1 natriuretic peptide receptor 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUP214 nucleoporin 214kDa
PAX3 paired box 3
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PINK1 PTEN induced putative kinase 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RECQL4 RecQ protein-like 4
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SGK223 homolog of rat pragma of Rnd2
SIK1 salt-inducible kinase 1
STK25 serine/threonine kinase 25
STK31 serine/threonine kinase 31
TEX14 testis expressed 14
TLN1 talin 1
TNK1 tyrosine kinase, non-receptor, 1
TNN tenascin N
TNRC6B trinucleotide repeat containing 6B
TP53 tumor protein p53
TP63 tumor protein p63
TRPS1 trichorhinophalangeal syndrome I
TSC2 tuberous sclerosis 2
TTN titin
VEGFC vascular endothelial growth factor C