7-aminocephalosporanic acid-1322 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 7-aminocephalosporanic acid-1322 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALG12 ALG12, alpha-1,6-mannosyltransferase
AOAH acyloxyacyl hydrolase (neutrophil)
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARMC7 armadillo repeat containing 7
ARMCX4 armadillo repeat containing, X-linked 4
ASPH aspartate beta-hydroxylase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATRN attractin
BAHCC1 BAH domain and coiled-coil containing 1
BBS9 Bardet-Biedl syndrome 9
BIN1 bridging integrator 1
C10ORF2 chromosome 10 open reading frame 2
C20ORF27 chromosome 20 open reading frame 27
C5 complement component 5
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CDR2L cerebellar degeneration-related protein 2-like
CENPT centromere protein T
CFP complement factor properdin
CHD3 chromodomain helicase DNA binding protein 3
COPS8 COP9 signalosome subunit 8
CPQ carboxypeptidase Q
CTSZ cathepsin Z
CUL7 cullin 7
DDAH2 dimethylarginine dimethylaminohydrolase 2
DEAF1 DEAF1 transcription factor
DOK5 docking protein 5
EPHB2 EPH receptor B2
FCF1 FCF1 rRNA-processing protein
GFOD2 glucose-fructose oxidoreductase domain containing 2
GPSM3 G-protein signaling modulator 3
HFE hemochromatosis
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HUS1 HUS1 checkpoint homolog (S. pombe)
IGFBP5 insulin-like growth factor binding protein 5
KAT8 K(lysine) acetyltransferase 8
KCTD2 potassium channel tetramerization domain containing 2
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAX MYC associated factor X
METTL7A methyltransferase like 7A
MINK1 misshapen-like kinase 1
MOB3B MOB kinase activator 3B
NAAA N-acylethanolamine acid amidase
NCALD neurocalcin delta
NLE1 notchless homolog 1 (Drosophila)
NR2F6 nuclear receptor subfamily 2, group F, member 6
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAX5 paired box 5
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEX10 peroxisomal biogenesis factor 10
PEX11A peroxisomal biogenesis factor 11 alpha
PLIN2 perilipin 2
PMP22 peripheral myelin protein 22
PTCRA pre T-cell antigen receptor alpha
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33A RAB33A, member RAS oncogene family
RANBP3 RAN binding protein 3
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBM48 RNA binding motif protein 48
RPL35A ribosomal protein L35a
SAPCD1 suppressor APC domain containing 1
SCAMP4 secretory carrier membrane protein 4
SCGB2A2 secretoglobin, family 2A, member 2
SIN3B SIN3 transcription regulator family member B
SIRT5 sirtuin 5
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMAD3 SMAD family member 3
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMYD2 SET and MYND domain containing 2
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOS2 son of sevenless homolog 2 (Drosophila)
SOX13 SRY (sex determining region Y)-box 13
SPEF1 sperm flagellar 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
ST7L suppression of tumorigenicity 7 like
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TERT telomerase reverse transcriptase
TESK1 testis-specific kinase 1
TEX40 testis expressed 40
THBS1 thrombospondin 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE3A ubiquitin protein ligase E3A
UBXN1 UBX domain protein 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFB vascular endothelial growth factor B
WFDC2 WAP four-disulfide core domain 2
WRAP53 WD repeat containing, antisense to TP53
ZMYND8 zinc finger, MYND-type containing 8
ZNF747 zinc finger protein 747
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AGO4 argonaute RISC catalytic component 4
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD40 ankyrin repeat domain 40
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
AUH AU RNA binding protein/enoyl-CoA hydratase
BAHD1 bromo adjacent homology domain containing 1
BHLHE41 basic helix-loop-helix family, member e41
BLVRB biliverdin reductase B
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C1ORF35 chromosome 1 open reading frame 35
C5AR1 complement component 5a receptor 1
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CCS copper chaperone for superoxide dismutase
CD48 CD48 molecule
CEP295 centrosomal protein 295kDa
CEP97 centrosomal protein 97kDa
COG4 component of oligomeric golgi complex 4
CSRNP2 cysteine-serine-rich nuclear protein 2
CYBA cytochrome b-245, alpha polypeptide
DFNA5 deafness, autosomal dominant 5
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
ERCC2 excision repair cross-complementation group 2
ERCC6L excision repair cross-complementation group 6-like
EXOC5 exocyst complex component 5
FAM127A family with sequence similarity 127, member A
FAM184A family with sequence similarity 184, member A
FES FES proto-oncogene, tyrosine kinase
FHIT fragile histidine triad
FLCN folliculin
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GMEB1 glucocorticoid modulatory element binding protein 1
GSTM3 glutathione S-transferase mu 3 (brain)
GTF2I general transcription factor IIi
GTPBP6 GTP binding protein 6 (putative)
HCFC2 host cell factor C2
HIST1H2BH histone cluster 1, H2bh
HSPA4L heat shock 70kDa protein 4-like
IGSF6 immunoglobulin superfamily, member 6
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAT2A K(lysine) acetyltransferase 2A
KLHL21 kelch-like family member 21
LAMP5 lysosomal-associated membrane protein family, member 5
LIG4 ligase IV, DNA, ATP-dependent
LIMD2 LIM domain containing 2
LINC00597 long intergenic non-protein coding RNA 597
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LRRK1 leucine-rich repeat kinase 1
LXN latexin
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MBD5 methyl-CpG binding domain protein 5
MDM4 MDM4, p53 regulator
MLYCD malonyl-CoA decarboxylase
NABP2 nucleic acid binding protein 2
NME3 NME/NM23 nucleoside diphosphate kinase 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIAS3 protein inhibitor of activated STAT, 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLS1 plastin 1
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAB8B RAB8B, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF122 ring finger protein 122
RNF25 ring finger protein 25
SHPK sedoheptulokinase
SIDT1 SID1 transmembrane family, member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMA4 glucuronidase, beta pseudogene
SP140L SP140 nuclear body protein-like
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SRD5A3 steroid 5 alpha-reductase 3
TBC1D17 TBC1 domain family, member 17
TBCCD1 TBCC domain containing 1
TCTN2 tectonic family member 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM242 transmembrane protein 242
TMEM38B transmembrane protein 38B
TMEM50B transmembrane protein 50B
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM25 tripartite motif containing 25
TSPYL2 TSPY-like 2
TUFT1 tuftelin 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB6 zinc finger and BTB domain containing 6
ZC2HC1A zinc finger, C2HC-type containing 1A
ZC3H12A zinc finger CCCH-type containing 12A
ZNF227 zinc finger protein 227
ZNF506 zinc finger protein 506
ZNF665 zinc finger protein 665