697 Gene Set

Dataset CCLE Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human B cell precursor leukemia; established from the bone marrow of a 12-year-old boy with acute lymphoblastic leukemia (cALL) at relapse in 1979. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001969)
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Genes

69 genes mutated in the 697 cell line from the CCLE Cell Line Gene Mutation Profiles dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ADAM17 ADAM metallopeptidase domain 17
ADAM28 ADAM metallopeptidase domain 28
ADGRG4 adhesion G protein-coupled receptor G4
AKAP9 A kinase (PRKA) anchor protein 9
ALPK1 alpha-kinase 1
ALPK2 alpha-kinase 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCR breakpoint cluster region
BIRC5 baculoviral IAP repeat containing 5
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CHD1 chromodomain helicase DNA binding protein 1
CLTCL1 clathrin, heavy chain-like 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSMD3 CUB and Sushi multiple domains 3
CTBP2 C-terminal binding protein 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
EP300 E1A binding protein p300
EPHA3 EPH receptor A3
EWSR1 EWS RNA-binding protein 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FN1 fibronectin 1
GLYATL2 glycine-N-acyltransferase-like 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GUCY2C guanylate cyclase 2C
HNF1A HNF1 homeobox A
ILK integrin-linked kinase
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB8 integrin, beta 8
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KLK7 kallikrein-related peptidase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK14 mitogen-activated protein kinase 14
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
NCAM1 neural cell adhesion molecule 1
NCOA3 nuclear receptor coactivator 3
NEK10 NIMA-related kinase 10
NEK3 NIMA-related kinase 3
NFIA nuclear factor I/A
NOTCH3 notch 3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR1 natriuretic peptide receptor 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAX3 paired box 3
PAX5 paired box 5
PDIK1L PDLIM1 interacting kinase 1 like
PGR progesterone receptor
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PRKD2 protein kinase D2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RECQL4 RecQ protein-like 4
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KL1 ribosomal protein S6 kinase-like 1
TGFB1 transforming growth factor, beta 1
TRRAP transformation/transcription domain-associated protein
TSSK3 testis-specific serine kinase 3
TTBK1 tau tubulin kinase 1
TTN titin
UBE3B ubiquitin protein ligase E3B
UNC79 unc-79 homolog (C. elegans)
VEGFC vascular endothelial growth factor C