639V Gene Set

Dataset CCLE Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: carcinoma, transitional cell (Cell Line Ontology, CLO_0001448)
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Genes

276 genes mutated in the 639V cell line from the CCLE Cell Line Gene Mutation Profiles dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACVR1 activin A receptor, type I
ACVR2B activin A receptor, type IIB
ADAM17 ADAM metallopeptidase domain 17
ADAM28 ADAM metallopeptidase domain 28
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADGRB3 adhesion G protein-coupled receptor B3
ADGRG4 adhesion G protein-coupled receptor G4
AGAP2-AS1 AGAP2 antisense RNA 1
ALPK2 alpha-kinase 2
AMHR2 anti-Mullerian hormone receptor, type II
ANAPC5 anaphase promoting complex subunit 5
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
AR androgen receptor
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP29 Rho GTPase activating protein 29
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARID1A AT rich interactive domain 1A (SWI-like)
ATM ATM serine/threonine kinase
ATP13A5 ATPase type 13A5
AXIN1 axin 1
AXIN2 axin 2
AXL AXL receptor tyrosine kinase
BAG6 BCL2-associated athanogene 6
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCNT1 cyclin T1
CCR4 chemokine (C-C motif) receptor 4
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDC5L cell division cycle 5-like
CDK5 cyclin-dependent kinase 5
CHD1 chromodomain helicase DNA binding protein 1
CHD5 chromodomain helicase DNA binding protein 5
CHN1 chimerin 1
CLTC clathrin, heavy chain (Hc)
CLTCL1 clathrin, heavy chain-like 1
CNTN6 contactin 6
COL14A1 collagen, type XIV, alpha 1
CPNE5 copine V
CREBBP CREB binding protein
CSPP1 centrosome and spindle pole associated protein 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAH8 dynein, axonemal, heavy chain 8
DVL1 dishevelled segment polarity protein 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4A1 eukaryotic translation initiation factor 4A1
ELN elastin
EP300 E1A binding protein p300
EPHA4 EPH receptor A4
EPHB2 EPH receptor B2
EPHB6 EPH receptor B6
FBXO43 F-box protein 43
FGFR1OP FGFR1 oncogene partner
FGFR3 fibroblast growth factor receptor 3
FGR FGR proto-oncogene, Src family tyrosine kinase
FKBP1A FK506 binding protein 1A, 12kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FMN2 formin 2
FNBP1 formin binding protein 1
FOXO4 forkhead box O4
FRS2 fibroblast growth factor receptor substrate 2
GCK glucokinase (hexokinase 4)
GLG1 golgi glycoprotein 1
GLI2 GLI family zinc finger 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPC3 glypican 3
GPHN gephyrin
GRAMD1B GRAM domain containing 1B
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRK4 G protein-coupled receptor kinase 4
GRK5 G protein-coupled receptor kinase 5
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY2C guanylate cyclase 2C
HDAC8 histone deacetylase 8
HDLBP high density lipoprotein binding protein
HIPK1 homeodomain interacting protein kinase 1
HOXA9 homeobox A9
HOXD11 homeobox D11
HSPA4 heat shock 70kDa protein 4
IGF1R insulin-like growth factor 1 receptor
IL1R2 interleukin 1 receptor, type II
IL6ST interleukin 6 signal transducer
ILK integrin-linked kinase
IRF4 interferon regulatory factor 4
ITGB4 integrin, beta 4
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAG1 jagged 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KAT6A K(lysine) acetyltransferase 6A
KDR kinase insert domain receptor
KLK7 kallikrein-related peptidase 7
KMT2C lysine (K)-specific methyltransferase 2C
KRAS Kirsten rat sarcoma viral oncogene homolog
KTN1 kinectin 1 (kinesin receptor)
LMNB2 lamin B2
LMO1 LIM domain only 1 (rhombotin 1)
LMTK3 lemur tyrosine kinase 3
LRP1 low density lipoprotein receptor-related protein 1
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
LRP6 low density lipoprotein receptor-related protein 6
MAK male germ cell-associated kinase
MALT1 MALT1 paracaspase
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK3 mitogen-activated protein kinase 3
MAPK4 mitogen-activated protein kinase 4
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MAST2 microtubule associated serine/threonine kinase 2
MCM4 minichromosome maintenance complex component 4
MECOM MDS1 and EVI1 complex locus
MED13L mediator complex subunit 13-like
MGA MGA, MAX dimerization protein
MINK1 misshapen-like kinase 1
MLH1 mutL homolog 1
MSH6 mutS homolog 6
MYLK myosin light chain kinase
MYO3A myosin IIIA
MYT1 myelin transcription factor 1
NCAM1 neural cell adhesion molecule 1
NCOA3 nuclear receptor coactivator 3
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEK3 NIMA-related kinase 3
NEK9 NIMA-related kinase 9
NLRP1 NLR family, pyrin domain containing 1
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH4 notch 4
NOVA1 neuro-oncological ventral antigen 1
NPAP1 nuclear pore associated protein 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR1 natriuretic peptide receptor 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRBP1 nuclear receptor binding protein 1
NUAK1 NUAK family, SNF1-like kinase, 1
NUMA1 nuclear mitotic apparatus protein 1
NUP98 nucleoporin 98kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OMG oligodendrocyte myelin glycoprotein
PAX3 paired box 3
PAX5 paired box 5
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCM1 pericentriolar material 1
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDZRN4 PDZ domain containing ring finger 4
PEAK1 pseudopodium-enriched atypical kinase 1
PHOX2B paired-like homeobox 2b
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRAME preferentially expressed antigen in melanoma
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PRKD2 protein kinase D2
PRKD3 protein kinase D3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PSEN1 presenilin 1
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRT protein tyrosine phosphatase, receptor type, T
RALGDS ral guanine nucleotide dissociation stimulator
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RB1 retinoblastoma 1
RBL1 retinoblastoma-like 1
RECQL4 RecQ protein-like 4
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGL3 ral guanine nucleotide dissociation stimulator-like 3
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SACS sacsin molecular chaperone
SCRIB scribbled planar cell polarity protein
SIK1 salt-inducible kinase 1
SIK3 SIK family kinase 3
SLC45A3 solute carrier family 45, member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNRK SNF related kinase
SNX19 sorting nexin 19
SOS1 son of sevenless homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT5B signal transducer and activator of transcription 5B
STK10 serine/threonine kinase 10
STK25 serine/threonine kinase 25
STK26 serine/threonine protein kinase 26
STK32A serine/threonine kinase 32A
STK35 serine/threonine kinase 35
STK36 serine/threonine kinase 36
STK39 serine threonine kinase 39
STRADB STE20-related kinase adaptor beta
STRN4 striatin, calmodulin binding protein 4
TCF3 transcription factor 3
TFDP1 transcription factor Dp-1
TFEB transcription factor EB
TFRC transferrin receptor
TGFBR1 transforming growth factor, beta receptor 1
TIAM1 T-cell lymphoma invasion and metastasis 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLK1 tousled-like kinase 1
TLR9 toll-like receptor 9
TMEM123 transmembrane protein 123
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNRC6B trinucleotide repeat containing 6B
TOE1 target of EGR1, member 1 (nuclear)
TOP1 topoisomerase (DNA) I
TOX thymocyte selection-associated high mobility group box
TP53 tumor protein p53
TP63 tumor protein p63
TRIB2 tribbles pseudokinase 2
TRIM28 tripartite motif containing 28
TRIO trio Rho guanine nucleotide exchange factor
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRRAP transformation/transcription domain-associated protein
TSC1 tuberous sclerosis 1
TSHR thyroid stimulating hormone receptor
TTBK1 tau tubulin kinase 1
TTN titin
TYK2 tyrosine kinase 2
VAV1 vav 1 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFC vascular endothelial growth factor C
VRK1 vaccinia related kinase 1
WNK1 WNK lysine deficient protein kinase 1
ZNF423 zinc finger protein 423
ZNF608 zinc finger protein 608