5707885-6390 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the 5707885-6390 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAM23 ADAM metallopeptidase domain 23
ADAP2 ArfGAP with dual PH domains 2
ALK anaplastic lymphoma receptor tyrosine kinase
APOL6 apolipoprotein L, 6
ARHGAP44 Rho GTPase activating protein 44
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPA aspartoacylase
ATN1 atrophin 1
C10ORF12 chromosome 10 open reading frame 12
CADM4 cell adhesion molecule 4
CARF calcium responsive transcription factor
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBS cystathionine-beta-synthase
CCDC9 coiled-coil domain containing 9
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC14A cell division cycle 14A
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHD5 chromodomain helicase DNA binding protein 5
CLCN1 chloride channel, voltage-sensitive 1
CLEC4M C-type lectin domain family 4, member M
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COMMD4 COMM domain containing 4
COPE coatomer protein complex, subunit epsilon
CTF1 cardiotrophin 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
DAGLA diacylglycerol lipase, alpha
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DSCAM Down syndrome cell adhesion molecule
EDN1 endothelin 1
EXD3 exonuclease 3'-5' domain containing 3
FAM149B1 family with sequence similarity 149, member B1
FGFR1 fibroblast growth factor receptor 1
FN1 fibronectin 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GEMIN8 gem (nuclear organelle) associated protein 8
GK glycerol kinase
GRK5 G protein-coupled receptor kinase 5
HHLA1 HERV-H LTR-associating 1
HLA-DMB major histocompatibility complex, class II, DM beta
HSF2 heat shock transcription factor 2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INSIG1 insulin induced gene 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB7 integrin, beta 7
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT6A keratin 6A, type II
LAMA4 laminin, alpha 4
LOC257152 uncharacterized LOC257152
LRRC23 leucine rich repeat containing 23
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK11 mitogen-activated protein kinase 11
MEF2D myocyte enhancer factor 2D
MMP19 matrix metallopeptidase 19
MST1 macrophage stimulating 1
MUC3A mucin 3A, cell surface associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEB nebulin
NEUROD4 neuronal differentiation 4
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE10A phosphodiesterase 10A
PIAS4 protein inhibitor of activated STAT, 4
PICALM phosphatidylinositol binding clathrin assembly protein
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLL polymerase (DNA directed), lambda
PPARD peroxisome proliferator-activated receptor delta
PPP5C protein phosphatase 5, catalytic subunit
PQLC2 PQ loop repeat containing 2
PRB1 proline-rich protein BstNI subfamily 1
PRPF18 pre-mRNA processing factor 18
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RUNX1 runt-related transcription factor 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SIRT3 sirtuin 3
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STX2 syntaxin 2
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
THRAP3 thyroid hormone receptor associated protein 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIB3 tribbles pseudokinase 3
TRIL TLR4 interactor with leucine-rich repeats
UNC5B unc-5 homolog B (C. elegans)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF428 zinc finger protein 428
ZNF44 zinc finger protein 44
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
AADAC arylacetamide deacetylase
ADGRF1 adhesion G protein-coupled receptor F1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARRB1 arrestin, beta 1
ATAD5 ATPase family, AAA domain containing 5
B9D2 B9 protein domain 2
BCAS1 breast carcinoma amplified sequence 1
BCL9 B-cell CLL/lymphoma 9
BTBD18 BTB (POZ) domain containing 18
C1ORF105 chromosome 1 open reading frame 105
CCNK cyclin K
CDK18 cyclin-dependent kinase 18
CEP41 centrosomal protein 41kDa
CHST10 carbohydrate sulfotransferase 10
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRMP1 collapsin response mediator protein 1
DIXDC1 DIX domain containing 1
DUSP2 dual specificity phosphatase 2
FAM110B family with sequence similarity 110, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF13 fibroblast growth factor 13
FGF6 fibroblast growth factor 6
FGL1 fibrinogen-like 1
FKRP fukutin related protein
GIF gastric intrinsic factor (vitamin B synthesis)
GJC1 gap junction protein, gamma 1, 45kDa
GMPR guanosine monophosphate reductase
GPR20 G protein-coupled receptor 20
HAS2 hyaluronan synthase 2
HIST1H3A histone cluster 1, H3a
HIST1H4C histone cluster 1, H4c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLX H2.0-like homeobox
HYAL3 hyaluronoglucosaminidase 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI44L interferon-induced protein 44-like
IL1R2 interleukin 1 receptor, type II
IL2 interleukin 2
IL20RA interleukin 20 receptor, alpha
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBB inhibin, beta B
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KIAA0895 KIAA0895
KIFC3 kinesin family member C3
KRT75 keratin 75, type II
LIME1 Lck interacting transmembrane adaptor 1
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LRRK1 leucine-rich repeat kinase 1
LSP1 lymphocyte-specific protein 1
LYRM9 LYR motif containing 9
MEGF8 multiple EGF-like-domains 8
MEOX1 mesenchyme homeobox 1
MRPL41 mitochondrial ribosomal protein L41
NDNF neuron-derived neurotrophic factor
PALMD palmdelphin
PCDHB1 protocadherin beta 1
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PGAM2 phosphoglycerate mutase 2 (muscle)
PGAP3 post-GPI attachment to proteins 3
PHLDA3 pleckstrin homology-like domain, family A, member 3
PRL prolactin
RAB40AL RAB40A, member RAS oncogene family-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
REC8 REC8 meiotic recombination protein
RPP25 ribonuclease P/MRP 25kDa subunit
SCG5 secretogranin V
SCIN scinderin
SEC14L5 SEC14-like 5 (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC12A9 solute carrier family 12, member 9
SLC17A2 solute carrier family 17, member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC46A3 solute carrier family 46, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNHG3 small nucleolar RNA host gene 3
SOSTDC1 sclerostin domain containing 1
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TCF15 transcription factor 15 (basic helix-loop-helix)
TDRD12 tudor domain containing 12
THRB thyroid hormone receptor, beta
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TMEM8B transmembrane protein 8B
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TXK TXK tyrosine kinase
TXNIP thioredoxin interacting protein
VASH2 vasohibin 2
WDR33 WD repeat domain 33
WT1-AS WT1 antisense RNA
ZNF35 zinc finger protein 35
ZNF667 zinc finger protein 667
ZNF675 zinc finger protein 675