5279552-960 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 5279552-960 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADGRE5 adhesion G protein-coupled receptor E5
AKR1C1 aldo-keto reductase family 1, member C1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APC adenomatous polyposis coli
ATF3 activating transcription factor 3
ATG4B autophagy related 4B, cysteine peptidase
BCL9 B-cell CLL/lymphoma 9
BMP1 bone morphogenetic protein 1
C14ORF79 chromosome 14 open reading frame 79
C1ORF105 chromosome 1 open reading frame 105
CCDC176 coiled-coil domain containing 176
CENPO centromere protein O
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DIAPH1 diaphanous-related formin 1
DSCAM Down syndrome cell adhesion molecule
DST dystonin
DTNA dystrobrevin, alpha
EPOR erythropoietin receptor
FBXL2 F-box and leucine-rich repeat protein 2
FCHSD2 FCH and double SH3 domains 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GK3P glycerol kinase 3 pseudogene
GMEB1 glucocorticoid modulatory element binding protein 1
GRB10 growth factor receptor-bound protein 10
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
HOXC10 homeobox C10
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
JUND jun D proto-oncogene
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0894 KIAA0894 protein
KIF18B kinesin family member 18B
KLF9 Kruppel-like factor 9
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAST4 microtubule associated serine/threonine kinase family member 4
MITF microphthalmia-associated transcription factor
MMP19 matrix metallopeptidase 19
MT1G metallothionein 1G
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPFFR1 neuropeptide FF receptor 1
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
PAPOLA poly(A) polymerase alpha
PCM1 pericentriolar material 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G3 phospholipase A2, group III
PLAGL2 pleiomorphic adenoma gene-like 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POLH polymerase (DNA directed), eta
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRICKLE3 prickle homolog 3 (Drosophila)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RHOBTB2 Rho-related BTB domain containing 2
RPAIN RPA interacting protein
RPL37A ribosomal protein L37a
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A11 S100 calcium binding protein A11
S100A8 S100 calcium binding protein A8
SCAI suppressor of cancer cell invasion
SCML2 sex comb on midleg-like 2 (Drosophila)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC3 syndecan 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SH2D4A SH2 domain containing 4A
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIDT2 SID1 transmembrane family, member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG5 SMG5 nonsense mediated mRNA decay factor
SOD2 superoxide dismutase 2, mitochondrial
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST7 suppression of tumorigenicity 7
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM231 transmembrane protein 231
TRA2A transformer 2 alpha homolog (Drosophila)
TRAPPC9 trafficking protein particle complex 9
UBAP2L ubiquitin associated protein 2-like
ZNF286A zinc finger protein 286A
ZNF500 zinc finger protein 500
ZNF721 zinc finger protein 721
ZNF76 zinc finger protein 76
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ABLIM3 actin binding LIM protein family, member 3
ADCY6 adenylate cyclase 6
AMPD2 adenosine monophosphate deaminase 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMC6 armadillo repeat containing 6
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BBC3 BCL2 binding component 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BPGM 2,3-bisphosphoglycerate mutase
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCDC94 coiled-coil domain containing 94
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CENPQ centromere protein Q
CGREF1 cell growth regulator with EF-hand domain 1
CLSTN2 calsyntenin 2
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRABP1 cellular retinoic acid binding protein 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DUSP8 dual specificity phosphatase 8
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGR3 early growth response 3
EHD3 EH-domain containing 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM114A2 family with sequence similarity 114, member A2
FAM63A family with sequence similarity 63, member A
FANCE Fanconi anemia, complementation group E
GHR growth hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H2AG histone cluster 1, H2ag
HMHA1 histocompatibility (minor) HA-1
HPSE heparanase
IGFBP6 insulin-like growth factor binding protein 6
IGFLR1 IGF-like family receptor 1
IPO8 importin 8
IRX4 iroquois homeobox 4
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LYPLA2P1 lysophospholipase II pseudogene 1
MTA2 metastasis associated 1 family, member 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTMR12 myotubularin related protein 12
MVD mevalonate (diphospho) decarboxylase
MYBBP1A MYB binding protein (P160) 1a
MYO9A myosin IXA
NCS1 neuronal calcium sensor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NISCH nischarin
NPY5R neuropeptide Y receptor Y5
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PCBP4 poly(rC) binding protein 4
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLD3 phospholipase D family, member 3
PP14571 uncharacterized LOC100130449
PRMT7 protein arginine methyltransferase 7
PRPH peripherin
PTCD2 pentatricopeptide repeat domain 2
RAB33B RAB33B, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
REPS2 RALBP1 associated Eps domain containing 2
RNF43 ring finger protein 43
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAMHD1 SAM domain and HD domain 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCD5 stearoyl-CoA desaturase 5
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SREBF1 sterol regulatory element binding transcription factor 1
STBD1 starch binding domain 1
STXBP2 syntaxin binding protein 2
SYBU syntabulin (syntaxin-interacting)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN1 tectonic family member 1
THOP1 thimet oligopeptidase 1
TMEM51 transmembrane protein 51
TOE1 target of EGR1, member 1 (nuclear)
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
WDR25 WD repeat domain 25
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZFP69B ZFP69 zinc finger protein B
ZNF35 zinc finger protein 35
ZNF492 zinc finger protein 492
ZNF586 zinc finger protein 586
ZNF668 zinc finger protein 668