5253409-961 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 5253409-961 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADM adrenomedullin
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ATF3 activating transcription factor 3
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
AURKA aurora kinase A
BHLHE40 basic helix-loop-helix family, member e40
C2ORF27A chromosome 2 open reading frame 27A
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CLDN1 claudin 1
COL2A1 collagen, type II, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CRYAB crystallin, alpha B
CSNK1G1 casein kinase 1, gamma 1
CSRP2 cysteine and glycine-rich protein 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DMC1 DNA meiotic recombinase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP1 dual specificity phosphatase 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDA ectodysplasin A
EGR1 early growth response 1
ERP44 endoplasmic reticulum protein 44
ETV5 ets variant 5
EXOC7 exocyst complex component 7
FANCA Fanconi anemia, complementation group A
FLJ22184
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
GEM GTP binding protein overexpressed in skeletal muscle
GREB1 growth regulation by estrogen in breast cancer 1
GSAP gamma-secretase activating protein
HEG1 heart development protein with EGF-like domains 1
HMOX1 heme oxygenase 1
HSPA1L heat shock 70kDa protein 1-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICOSLG inducible T-cell co-stimulator ligand
IER5 immediate early response 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL17RA interleukin 17 receptor A
IL2RB interleukin 2 receptor, beta
IQCK IQ motif containing K
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KCNK15 potassium channel, two pore domain subfamily K, member 15
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
LAT2 linker for activation of T cells family, member 2
LOC644450 uncharacterized LOC644450
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGOH2P mago-nashi homolog 2, pseudogene
MAOB monoamine oxidase B
MAP1B microtubule-associated protein 1B
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MITF microphthalmia-associated transcription factor
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTRF1L mitochondrial translational release factor 1-like
MYO10 myosin X
MYO9B myosin IXB
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NXPE3 neurexophilin and PC-esterase domain family, member 3
OVOL1 ovo-like zinc finger 1
PDE9A phosphodiesterase 9A
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAGL1 pleiomorphic adenoma gene-like 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RABGAP1 RAB GTPase activating protein 1
RARA retinoic acid receptor, alpha
RGS2 regulator of G-protein signaling 2
RHOQ ras homolog family member Q
ROM1 retinal outer segment membrane protein 1
RPL10 ribosomal protein L10
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BGR SH3 domain binding glutamate-rich protein
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMG5 SMG5 nonsense mediated mRNA decay factor
SND1-IT1 SND1 intronic transcript 1
TMEM144 transmembrane protein 144
TMEM53 transmembrane protein 53
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN9 tetraspanin 9
TSPYL2 TSPY-like 2
UBE2I ubiquitin-conjugating enzyme E2I
USP12 ubiquitin specific peptidase 12
USP36 ubiquitin specific peptidase 36
WDR62 WD repeat domain 62
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF10 zinc finger protein 10
ZNF444 zinc finger protein 444
ZNF76 zinc finger protein 76
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
AKAP12 A kinase (PRKA) anchor protein 12
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASTE1 asteroid homolog 1 (Drosophila)
BAK1 BCL2-antagonist/killer 1
BCL9 B-cell CLL/lymphoma 9
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF115 chromosome 1 open reading frame 115
C1ORF216 chromosome 1 open reading frame 216
CCNE2 cyclin E2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPQ centromere protein Q
CGREF1 cell growth regulator with EF-hand domain 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLSPN claspin
CORO1A coronin, actin binding protein, 1A
EFNA4 ephrin-A4
EGLN3 egl-9 family hypoxia-inducible factor 3
EPN3 epsin 3
ETAA1 Ewing tumor-associated antigen 1
FAM155B family with sequence similarity 155, member B
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FBXO5 F-box protein 5
FKBPL FK506 binding protein like
FOXC1 forkhead box C1
FPGT fucose-1-phosphate guanylyltransferase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLCE glucuronic acid epimerase
IGSF1 immunoglobulin superfamily, member 1
IL15RA interleukin 15 receptor, alpha
INSIG2 insulin induced gene 2
JRKL JRK-like
KAT2A K(lysine) acetyltransferase 2A
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0232 KIAA0232
KIFAP3 kinesin-associated protein 3
KPTN kaptin (actin binding protein)
LEMD3 LEM domain containing 3
MANEA mannosidase, endo-alpha
MB myoglobin
MDM4 MDM4, p53 regulator
MID1IP1 MID1 interacting protein 1
MMP9 matrix metallopeptidase 9
MORC3 MORC family CW-type zinc finger 3
NECAB3 N-terminal EF-hand calcium binding protein 3
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NRGN neurogranin (protein kinase C substrate, RC3)
NUBPL nucleotide binding protein-like
NUP62CL nucleoporin 62kDa C-terminal like
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCNXL4 pecanex-like 4 (Drosophila)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PP14571 uncharacterized LOC100130449
PRPF38B pre-mRNA processing factor 38B
PRR15L proline rich 15-like
RAB17 RAB17, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAD51AP1 RAD51 associated protein 1
REEP4 receptor accessory protein 4
RGS19 regulator of G-protein signaling 19
RLN2 relaxin 2
RPL23AP7 ribosomal protein L23a pseudogene 7
SCAMP4 secretory carrier membrane protein 4
SLC22A18 solute carrier family 22, member 18
SLC46A3 solute carrier family 46, member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SREBF1 sterol regulatory element binding transcription factor 1
STX10 syntaxin 10
SUOX sulfite oxidase
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMPRSS3 transmembrane protease, serine 3
TNRC6B trinucleotide repeat containing 6B
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPS1 trichorhinophalangeal syndrome I
TWSG1 twisted gastrulation BMP signaling modulator 1
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
WDR19 WD repeat domain 19
YIPF3 Yip1 domain family, member 3
ZBED8 zinc finger, BED-type containing 8
ZBTB3 zinc finger and BTB domain containing 3
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF516 zinc finger protein 516
ZNF573 zinc finger protein 573
ZNF669 zinc finger protein 669
ZNF770 zinc finger protein 770
ZSCAN31 zinc finger and SCAN domain containing 31