5252917-944 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the 5252917-944 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ADCY3 adenylate cyclase 3
ALOX15 arachidonate 15-lipoxygenase
AREG amphiregulin
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL15 ADP-ribosylation factor-like 15
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASTN2 astrotactin 2
ATF3 activating transcription factor 3
ATP9A ATPase, class II, type 9A
ATXN1 ataxin 1
BIN1 bridging integrator 1
BTN2A2 butyrophilin, subfamily 2, member A2
CBX7 chromobox homolog 7
CCDC186 coiled-coil domain containing 186
CISH cytokine inducible SH2-containing protein
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DESI2 desumoylating isopeptidase 2
DOCK1 dedicator of cytokinesis 1
DTNA dystrobrevin, alpha
DUSP4 dual specificity phosphatase 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
EXOC7 exocyst complex component 7
FGD6 FYVE, RhoGEF and PH domain containing 6
FOSL2 FOS-like antigen 2
FOXO1 forkhead box O1
GMEB2 glucocorticoid modulatory element binding protein 2
GPX2 glutathione peroxidase 2
ICOSLG inducible T-cell co-stimulator ligand
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
KAT5 K(lysine) acetyltransferase 5
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLHL24 kelch-like family member 24
KRT15 keratin 15, type I
LAMB3 laminin, beta 3
LOC644450 uncharacterized LOC644450
LPIN1 lipin 1
LRP5 low density lipoprotein receptor-related protein 5
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MED6 mediator complex subunit 6
MGLL monoglyceride lipase
MITF microphthalmia-associated transcription factor
MYO1B myosin IB
MYOF myoferlin
NCAPH2 non-SMC condensin II complex, subunit H2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGLY1 N-glycanase 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAPOLA poly(A) polymerase alpha
PCM1 pericentriolar material 1
PGPEP1 pyroglutamyl-peptidase I
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RABGAP1L RAB GTPase activating protein 1-like
RPS11 ribosomal protein S11
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SAMD4A sterile alpha motif domain containing 4A
SCML2 sex comb on midleg-like 2 (Drosophila)
SHB Src homology 2 domain containing adaptor protein B
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SND1-IT1 SND1 intronic transcript 1
SNORA21 small nucleolar RNA, H/ACA box 21
SOGA1 suppressor of glucose, autophagy associated 1
SOX13 SRY (sex determining region Y)-box 13
SRF serum response factor (c-fos serum response element-binding transcription factor)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STXBP6 syntaxin binding protein 6 (amisyn)
SUN2 Sad1 and UNC84 domain containing 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TEAD3 TEA domain family member 3
TGFB2 transforming growth factor, beta 2
TGFBI transforming growth factor, beta-induced, 68kDa
TGM2 transglutaminase 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR2 toll-like receptor 2
TNK1 tyrosine kinase, non-receptor, 1
TRAK1 trafficking protein, kinesin binding 1
TRIO trio Rho guanine nucleotide exchange factor
UBQLN4 ubiquilin 4
VEGFA vascular endothelial growth factor A
YLPM1 YLP motif containing 1
ZNF451 zinc finger protein 451
ZNF76 zinc finger protein 76
ZYX zyxin

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
APOC1 apolipoprotein C-I
ARMC7 armadillo repeat containing 7
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BMP4 bone morphogenetic protein 4
BTBD2 BTB (POZ) domain containing 2
C16ORF59 chromosome 16 open reading frame 59
C5ORF45 chromosome 5 open reading frame 45
CCNE1 cyclin E1
CCP110 centriolar coiled coil protein 110kDa
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLSPN claspin
CORO1A coronin, actin binding protein, 1A
CRBN cereblon
CTSV cathepsin V
CXORF56 chromosome X open reading frame 56
EHD3 EH-domain containing 3
EIF5A2 eukaryotic translation initiation factor 5A2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FANCE Fanconi anemia, complementation group E
FBRS fibrosin
FOXC1 forkhead box C1
FPGT fucose-1-phosphate guanylyltransferase
FRS2 fibroblast growth factor receptor substrate 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GSTM2 glutathione S-transferase mu 2 (muscle)
HELLS helicase, lymphoid-specific
HIST1H2AC histone cluster 1, H2ac
HIST1H2AM histone cluster 1, H2am
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HPS6 Hermansky-Pudlak syndrome 6
IGFLR1 IGF-like family receptor 1
IMPACT impact RWD domain protein
INF2 inverted formin, FH2 and WH2 domain containing
IRF7 interferon regulatory factor 7
KAT2B K(lysine) acetyltransferase 2B
KCTD20 potassium channel tetramerization domain containing 20
KDM5C lysine (K)-specific demethylase 5C
KLHL26 kelch-like family member 26
LINC00115 long intergenic non-protein coding RNA 115
MAP6D1 MAP6 domain containing 1
MAPK3 mitogen-activated protein kinase 3
MOGS mannosyl-oligosaccharide glucosidase
MOSPD3 motile sperm domain containing 3
MTERF1 mitochondrial transcription termination factor 1
NARFL nuclear prelamin A recognition factor-like
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NKAIN1 Na+/K+ transporting ATPase interacting 1
PARD6A par-6 family cell polarity regulator alpha
PARP12 poly (ADP-ribose) polymerase family, member 12
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLD3 phospholipase D family, member 3
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
QTRT1 queuine tRNA-ribosyltransferase 1
RBL1 retinoblastoma-like 1
RBM14 RNA binding motif protein 14
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPGR retinitis pigmentosa GTPase regulator
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SESN1 sestrin 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC35A5 solute carrier family 35, member A5
SMAD7 SMAD family member 7
SMCO4 single-pass membrane protein with coiled-coil domains 4
STX5 syntaxin 5
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TEX264 testis expressed 264
TKFC triokinase/FMN cyclase
TMEM132A transmembrane protein 132A
TMEM183A transmembrane protein 183A
TRIM45 tripartite motif containing 45
TRIM5 tripartite motif containing 5
TRIM52 tripartite motif containing 52
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPAN1 tetraspanin 1
TUBA4A tubulin, alpha 4a
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
WDR91 WD repeat domain 91
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF324 zinc finger protein 324
ZNF468 zinc finger protein 468
ZNF552 zinc finger protein 552
ZNF557 zinc finger protein 557
ZNF586 zinc finger protein 586
ZNF813 zinc finger protein 813
ZNHIT2 zinc finger, HIT-type containing 2