5248896-955 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 5248896-955 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
APC adenomatous polyposis coli
BTG2 BTG family, member 2
C17ORF59 chromosome 17 open reading frame 59
C7ORF43 chromosome 7 open reading frame 43
CLEC4M C-type lectin domain family 4, member M
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMID1 EMI domain containing 1
EXOC7 exocyst complex component 7
FAM214B family with sequence similarity 214, member B
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
GON4L gon-4-like (C. elegans)
GREB1L growth regulation by estrogen in breast cancer-like
GSTCD glutathione S-transferase, C-terminal domain containing
HBEGF heparin-binding EGF-like growth factor
HEMK1 HemK methyltransferase family member 1
HFE hemochromatosis
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2BJ histone cluster 1, H2bj
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA5 homeobox A5
HOXC13 homeobox C13
IDI2-AS1 IDI2 antisense RNA 1
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0125 KIAA0125
KLF2 Kruppel-like factor 2
LOC644450 uncharacterized LOC644450
LPIN1 lipin 1
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBD1 methyl-CpG binding domain protein 1
MED6 mediator complex subunit 6
METTL5 methyltransferase like 5
MVK mevalonate kinase
MYO1F myosin IF
MYOZ3 myozenin 3
N4BP2L2 NEDD4 binding protein 2-like 2
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NAAA N-acylethanolamine acid amidase
NAIP NLR family, apoptosis inhibitory protein
NPC1 Niemann-Pick disease, type C1
NRF1 nuclear respiratory factor 1
NUPR1 nuclear protein, transcriptional regulator, 1
OVOL2 ovo-like zinc finger 2
PDCD6 programmed cell death 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD2 phospholipase D2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PSG9 pregnancy specific beta-1-glycoprotein 9
PTDSS2 phosphatidylserine synthase 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PVT1 Pvt1 oncogene (non-protein coding)
RAB32 RAB32, member RAS oncogene family
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHOQ ras homolog family member Q
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RXRA retinoid X receptor, alpha
SCARB1 scavenger receptor class B, member 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SIK3 SIK family kinase 3
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STRN striatin, calmodulin binding protein
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAPBP TAP binding protein (tapasin)
TMCO6 transmembrane and coiled-coil domains 6
TMPRSS2 transmembrane protease, serine 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
ULK2 unc-51 like autophagy activating kinase 2
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WASL Wiskott-Aldrich syndrome-like
WDR61 WD repeat domain 61
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF10 zinc finger protein 10
ZNF3 zinc finger protein 3
ZNF444 zinc finger protein 444
ZNF571 zinc finger protein 571
ZNF767P zinc finger family member 767, pseudogene
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ALDOC aldolase C, fructose-bisphosphate
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMOTL2 angiomotin like 2
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATP7B ATPase, Cu++ transporting, beta polypeptide
BRAF B-Raf proto-oncogene, serine/threonine kinase
C5ORF45 chromosome 5 open reading frame 45
DBR1 debranching RNA lariats 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DESI1 desumoylating isopeptidase 1
E2F8 E2F transcription factor 8
EFHD2 EF-hand domain family, member D2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPN3 epsin 3
FAAH fatty acid amide hydrolase
FANCE Fanconi anemia, complementation group E
FAR2 fatty acyl CoA reductase 2
FZD2 frizzled class receptor 2
GHR growth hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLCE glucuronic acid epimerase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR87 G protein-coupled receptor 87
GTF2I general transcription factor IIi
GTPBP8 GTP-binding protein 8 (putative)
HIRIP3 HIRA interacting protein 3
HIST1H1C histone cluster 1, H1c
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BE histone cluster 1, H2be
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IGFBP6 insulin-like growth factor binding protein 6
IRF6 interferon regulatory factor 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JRKL JRK-like
L2HGDH L-2-hydroxyglutarate dehydrogenase
LRRC37A2 leucine rich repeat containing 37, member A2
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MED15 mediator complex subunit 15
MED22 mediator complex subunit 22
MTA2 metastasis associated 1 family, member 2
MYO19 myosin XIX
NT5E 5'-nucleotidase, ecto (CD73)
OGFRL1 opioid growth factor receptor-like 1
OSMR oncostatin M receptor
PER3 period circadian clock 3
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PPT2 palmitoyl-protein thioesterase 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTPRE protein tyrosine phosphatase, receptor type, E
PXMP4 peroxisomal membrane protein 4, 24kDa
QTRT1 queuine tRNA-ribosyltransferase 1
RBM42 RNA binding motif protein 42
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNH1 ribonuclease/angiogenin inhibitor 1
RPH3AL rabphilin 3A-like (without C2 domains)
SALL2 spalt-like transcription factor 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCAMP5 secretory carrier membrane protein 5
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH2B3 SH2B adaptor protein 3
SHPK sedoheptulokinase
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SPIN1 spindlin 1
STX5 syntaxin 5
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TCTN2 tectonic family member 2
THAP1 THAP domain containing, apoptosis associated protein 1
TMCO3 transmembrane and coiled-coil domains 3
TMEM115 transmembrane protein 115
TMEM254 transmembrane protein 254
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNRC6B trinucleotide repeat containing 6B
TRIM5 tripartite motif containing 5
TRIM66 tripartite motif containing 66
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
USP18 ubiquitin specific peptidase 18
VCPKMT valosin containing protein lysine (K) methyltransferase
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF432 zinc finger protein 432
ZNF492 zinc finger protein 492
ZNF557 zinc finger protein 557
ZNF574 zinc finger protein 574
ZNF669 zinc finger protein 669
ZNF74 zinc finger protein 74
ZSCAN31 zinc finger and SCAN domain containing 31