5230742-970 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the 5230742-970 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ADM adrenomedullin
AKAP10 A kinase (PRKA) anchor protein 10
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ASB6 ankyrin repeat and SOCS box containing 6
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C7ORF43 chromosome 7 open reading frame 43
CA4 carbonic anhydrase IV
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CDK16 cyclin-dependent kinase 16
CEP164 centrosomal protein 164kDa
CFAP44 cilia and flagella associated protein 44
CLCN2 chloride channel, voltage-sensitive 2
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DICER1 dicer 1, ribonuclease type III
DVL3 dishevelled segment polarity protein 3
DZIP3 DAZ interacting zinc finger protein 3
EFHC2 EF-hand domain (C-terminal) containing 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FANCA Fanconi anemia, complementation group A
FBXW12 F-box and WD repeat domain containing 12
FGFR1 fibroblast growth factor receptor 1
FKBP10 FK506 binding protein 10, 65 kDa
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GEM GTP binding protein overexpressed in skeletal muscle
GFI1 growth factor independent 1 transcription repressor
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLS glutaminase
HMOX1 heme oxygenase 1
INPP1 inositol polyphosphate-1-phosphatase
IPO9 importin 9
IRS2 insulin receptor substrate 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK5 potassium channel, two pore domain subfamily K, member 5
KDM8 lysine (K)-specific demethylase 8
LOC257152 uncharacterized LOC257152
LOC644450 uncharacterized LOC644450
LRRC14 leucine rich repeat containing 14
LRRC37A3 leucine rich repeat containing 37, member A3
LYPD1 LY6/PLAUR domain containing 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
METTL7A methyltransferase like 7A
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MID1 midline 1
MKL1 megakaryoblastic leukemia (translocation) 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MZF1 myeloid zinc finger 1
MZT2B mitotic spindle organizing protein 2B
NEUROD1 neuronal differentiation 1
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NT5DC3 5'-nucleotidase domain containing 3
PBX2 pre-B-cell leukemia homeobox 2
PHF14 PHD finger protein 14
PHKA2 phosphorylase kinase, alpha 2 (liver)
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PILRB paired immunoglobin-like type 2 receptor beta
PINK1 PTEN induced putative kinase 1
PLXNA3 plexin A3
POFUT2 protein O-fucosyltransferase 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RNF216 ring finger protein 216
SAFB2 scaffold attachment factor B2
SBF1 SET binding factor 1
SCAI suppressor of cancer cell invasion
SETD1A SET domain containing 1A
SIGLEC15 sialic acid binding Ig-like lectin 15
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX13 SRY (sex determining region Y)-box 13
TIMP4 TIMP metallopeptidase inhibitor 4
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VIPR1 vasoactive intestinal peptide receptor 1
WDR62 WD repeat domain 62
WIPF1 WAS/WASL interacting protein family, member 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF202 zinc finger protein 202
ZNF250 zinc finger protein 250
ZNF362 zinc finger protein 362
ZNF710 zinc finger protein 710
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATP7B ATPase, Cu++ transporting, beta polypeptide
BBS7 Bardet-Biedl syndrome 7
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF30 chromosome 11 open reading frame 30
CAMTA1 calmodulin binding transcription activator 1
CBX4 chromobox homolog 4
CCNT1 cyclin T1
CENPQ centromere protein Q
CEP97 centrosomal protein 97kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHIC2 cysteine-rich hydrophobic domain 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLCN5 chloride channel, voltage-sensitive 5
CLK4 CDC-like kinase 4
COL4A5 collagen, type IV, alpha 5
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUEDC1 CUE domain containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DEPDC1 DEP domain containing 1
DTX4 deltex 4, E3 ubiquitin ligase
EFCAB2 EF-hand calcium binding domain 2
EGR3 early growth response 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML4 echinoderm microtubule associated protein like 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EVPL envoplakin
EXOC5 exocyst complex component 5
FAM172A family with sequence similarity 172, member A
FKBP5 FK506 binding protein 5
FOXC1 forkhead box C1
FPGT fucose-1-phosphate guanylyltransferase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR87 G protein-coupled receptor 87
GSTM1 glutathione S-transferase mu 1
GTF2I general transcription factor IIi
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HIST1H2AM histone cluster 1, H2am
HMGB3P1 high mobility group box 3 pseudogene 1
IGFBP6 insulin-like growth factor binding protein 6
IPO8 importin 8
KAT2B K(lysine) acetyltransferase 2B
KCTD20 potassium channel tetramerization domain containing 20
KIAA1551 KIAA1551
KIF18A kinesin family member 18A
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMNB1 lamin B1
MANSC1 MANSC domain containing 1
MAP7D3 MAP7 domain containing 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MEIS1 Meis homeobox 1
MPDU1 mannose-P-dolichol utilization defect 1
MRPL52 mitochondrial ribosomal protein L52
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NRGN neurogranin (protein kinase C substrate, RC3)
PDZK1 PDZ domain containing 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PTCD2 pentatricopeptide repeat domain 2
PTPRE protein tyrosine phosphatase, receptor type, E
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SAMHD1 SAM domain and HD domain 1
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC31A2 solute carrier family 31 (copper transporter), member 2
SMAD7 SMAD family member 7
SNRPF small nuclear ribonucleoprotein polypeptide F
SNX16 sorting nexin 16
STK16 serine/threonine kinase 16
STXBP2 syntaxin binding protein 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBCC tubulin folding cofactor C
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TET3 tet methylcytosine dioxygenase 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF3 transmembrane 7 superfamily member 3
TMEM230 transmembrane protein 230
TMOD3 tropomodulin 3 (ubiquitous)
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNRC6B trinucleotide repeat containing 6B
ULBP2 UL16 binding protein 2
USP18 ubiquitin specific peptidase 18
ZFP69B ZFP69 zinc finger protein B
ZNF184 zinc finger protein 184
ZNF516 zinc finger protein 516
ZNF770 zinc finger protein 770
ZNHIT2 zinc finger, HIT-type containing 2