5186324-900 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 5186324-900 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
APAF1 apoptotic peptidase activating factor 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
C5 complement component 5
CCDC28B coiled-coil domain containing 28B
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDKL3 cyclin-dependent kinase-like 3
CTNND2 catenin (cadherin-associated protein), delta 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EN2 engrailed homeobox 2
ENGASE endo-beta-N-acetylglucosaminidase
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EVA1B eva-1 homolog B (C. elegans)
EXOC7 exocyst complex component 7
FADS3 fatty acid desaturase 3
FAS Fas cell surface death receptor
FBXL18 F-box and leucine-rich repeat protein 18
FGF23 fibroblast growth factor 23
FLCN folliculin
FOXJ3 forkhead box J3
FRS2 fibroblast growth factor receptor substrate 2
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GBP2 guanylate binding protein 2, interferon-inducible
GID4 GID complex subunit 4
GLI3 GLI family zinc finger 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
GRM8 glutamate receptor, metabotropic 8
HFE hemochromatosis
HIPK2 homeodomain interacting protein kinase 2
HNMT histamine N-methyltransferase
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRF6 interferon regulatory factor 6
KDM5A lysine (K)-specific demethylase 5A
LHX6 LIM homeobox 6
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LNPEP leucyl/cystinyl aminopeptidase
LOC100287590 uncharacterized LOC100287590
LONP2 lon peptidase 2, peroxisomal
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MCM3AP minichromosome maintenance complex component 3 associated protein
MRPL44 mitochondrial ribosomal protein L44
MTCL1 microtubule crosslinking factor 1
MUC1 mucin 1, cell surface associated
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
OVGP1 oviductal glycoprotein 1, 120kDa
PDE12 phosphodiesterase 12
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM5 PDZ and LIM domain 5
PGAP1 post-GPI attachment to proteins 1
PHACTR4 phosphatase and actin regulator 4
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLK4 polo-like kinase 4
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RASA2 RAS p21 protein activator 2
REPS1 RALBP1 associated Eps domain containing 1
RNF24 ring finger protein 24
RRP1B ribosomal RNA processing 1B
RUNDC3B RUN domain containing 3B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIAH1 siah E3 ubiquitin protein ligase 1
SIX1 SIX homeobox 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMTN smoothelin
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SPRED2 sprouty-related, EVH1 domain containing 2
SUGP1 SURP and G patch domain containing 1
TAOK1 TAO kinase 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TM2D1 TM2 domain containing 1
TPTE transmembrane phosphatase with tensin homology
UBIAD1 UbiA prenyltransferase domain containing 1
USP34 ubiquitin specific peptidase 34
VAC14 Vac14 homolog (S. cerevisiae)
VIPR1 vasoactive intestinal peptide receptor 1
WWOX WW domain containing oxidoreductase
ZMYM5 zinc finger, MYM-type 5
ZNF227 zinc finger protein 227
ZNF350 zinc finger protein 350
ZNF365 zinc finger protein 365
ZNF562 zinc finger protein 562
ZNF767P zinc finger family member 767, pseudogene

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABHD17B abhydrolase domain containing 17B
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANPEP alanyl (membrane) aminopeptidase
ARHGAP10 Rho GTPase activating protein 10
ATG2B autophagy related 2B
AZI2 5-azacytidine induced 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHCC1 BAH domain and coiled-coil containing 1
BBC3 BCL2 binding component 3
BMP4 bone morphogenetic protein 4
C11ORF68 chromosome 11 open reading frame 68
C11ORF80 chromosome 11 open reading frame 80
C14ORF93 chromosome 14 open reading frame 93
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
CHML choroideremia-like (Rab escort protein 2)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRIP1 cysteine-rich protein 1 (intestinal)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DMTN dematin actin binding protein
DNALI1 dynein, axonemal, light intermediate chain 1
DSPP dentin sialophosphoprotein
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFCAB2 EF-hand calcium binding domain 2
EMID1 EMI domain containing 1
ETAA1 Ewing tumor-associated antigen 1
EYA3 EYA transcriptional coactivator and phosphatase 3
F8 coagulation factor VIII, procoagulant component
FAM86C1 family with sequence similarity 86, member C1
FLJ22184
FOSL1 FOS-like antigen 1
GDAP1 ganglioside induced differentiation associated protein 1
GHR growth hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPATCH3 G patch domain containing 3
GPR37L1 G protein-coupled receptor 37 like 1
GTF2I general transcription factor IIi
HIRA histone cell cycle regulator
HIST1H2AI histone cluster 1, H2ai
HMHA1 histocompatibility (minor) HA-1
HOXC8 homeobox C8
HYI hydroxypyruvate isomerase (putative)
INCENP inner centromere protein antigens 135/155kDa
KIAA0125 KIAA0125
KRT15 keratin 15, type I
LHX1 LIM homeobox 1
LMBR1L limb development membrane protein 1-like
LOC257152 uncharacterized LOC257152
LRRC37A2 leucine rich repeat containing 37, member A2
LYPD1 LY6/PLAUR domain containing 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MON1B MON1 secretory trafficking family member B
NAG18 NAG18 mRNA
NPTX1 neuronal pentraxin I
NUPL2 nucleoporin like 2
PCDHA5 protocadherin alpha 5
PCDHB13 protocadherin beta 13
PELI1 pellino E3 ubiquitin protein ligase 1
PMP22 peripheral myelin protein 22
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PROCR protein C receptor, endothelial
PTDSS2 phosphatidylserine synthase 2
RAB35 RAB35, member RAS oncogene family
RAPSN receptor-associated protein of the synapse
RHOBTB2 Rho-related BTB domain containing 2
SCN1B sodium channel, voltage gated, type I beta subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
STX5 syntaxin 5
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAF2 TNF receptor-associated factor 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
USP27X ubiquitin specific peptidase 27, X-linked
VAV1 vav 1 guanine nucleotide exchange factor
WDR91 WD repeat domain 91
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF34 zinc finger protein 34
ZNF516 zinc finger protein 516
ZNF665 zinc finger protein 665
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675