5182598-976 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 5182598-976 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABHD4 abhydrolase domain containing 4
ADAM17 ADAM metallopeptidase domain 17
ADAP1 ArfGAP with dual PH domains 1
ADCY7 adenylate cyclase 7
AKAP17A A kinase (PRKA) anchor protein 17A
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATF3 activating transcription factor 3
BAIAP2 BAI1-associated protein 2
CBR3 carbonyl reductase 3
CC2D1A coiled-coil and C2 domain containing 1A
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FECH ferrochelatase
FKBP10 FK506 binding protein 10, 65 kDa
FLJ22184
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GLS glutaminase
GPX2 glutathione peroxidase 2
GRIK5 glutamate receptor, ionotropic, kainate 5
HLA-J major histocompatibility complex, class I, J (pseudogene)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INHBE inhibin, beta E
IPO9 importin 9
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD13 potassium channel tetramerization domain containing 13
LPIN1 lipin 1
LPXN leupaxin
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRP5 low density lipoprotein receptor-related protein 5
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MBD1 methyl-CpG binding domain protein 1
MIR22HG MIR22 host gene
MMP19 matrix metallopeptidase 19
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
N4BP2L2 NEDD4 binding protein 2-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRCAM neuronal cell adhesion molecule
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDCD6 programmed cell death 6
PELO pelota homolog (Drosophila)
PHC3 polyhomeotic homolog 3 (Drosophila)
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTCH1 patched 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGCC regulator of cell cycle
RHOQ ras homolog family member Q
RIT1 Ras-like without CAAX 1
ROM1 retinal outer segment membrane protein 1
RPAIN RPA interacting protein
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3BP2 SH3-domain binding protein 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SQSTM1 sequestosome 1
SREBF2 sterol regulatory element binding transcription factor 2
SRRM2 serine/arginine repetitive matrix 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TPST2 tyrosylprotein sulfotransferase 2
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TRIO trio Rho guanine nucleotide exchange factor
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
UNKL unkempt family zinc finger-like
VEGFA vascular endothelial growth factor A
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
AHR aryl hydrocarbon receptor
AKAP12 A kinase (PRKA) anchor protein 12
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMCX1 armadillo repeat containing, X-linked 1
ATP11B ATPase, class VI, type 11B
B3GNT1
BAMBI BMP and activin membrane-bound inhibitor
BEX4 brain expressed, X-linked 4
BIK BCL2-interacting killer (apoptosis-inducing)
BMP4 bone morphogenetic protein 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF106 chromosome 1 open reading frame 106
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC28A coiled-coil domain containing 28A
CHST10 carbohydrate sulfotransferase 10
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
FAM63A family with sequence similarity 63, member A
FASTKD1 FAST kinase domains 1
FMO4 flavin containing monooxygenase 4
FUZ fuzzy planar cell polarity protein
GCHFR GTP cyclohydrolase I feedback regulator
GHR growth hormone receptor
GLCE glucuronic acid epimerase
GSTM2 glutathione S-transferase mu 2 (muscle)
HOXA5 homeobox A5
HOXC11 homeobox C11
HOXC13 homeobox C13
HOXC6 homeobox C6
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
ICK intestinal cell (MAK-like) kinase
IL10RB interleukin 10 receptor, beta
IRF6 interferon regulatory factor 6
JUNB jun B proto-oncogene
KCTD20 potassium channel tetramerization domain containing 20
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KIAA0895 KIAA0895
KIF3A kinesin family member 3A
KIFAP3 kinesin-associated protein 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIMA1 LIM domain and actin binding 1
LMCD1 LIM and cysteine-rich domains 1
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEH1 melanoma antigen family H1
MANSC1 MANSC domain containing 1
MEIS1 Meis homeobox 1
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
NUP62CL nucleoporin 62kDa C-terminal like
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PCTP phosphatidylcholine transfer protein
PELI1 pellino E3 ubiquitin protein ligase 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLEK2 pleckstrin 2
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR15L proline rich 15-like
PRSS8 protease, serine, 8
RAB8B RAB8B, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS16 regulator of G-protein signaling 16
RLN2 relaxin 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD3 RWD domain containing 3
SALL2 spalt-like transcription factor 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC46A3 solute carrier family 46, member 3
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOAT1 sterol O-acyltransferase 1
SPATA7 spermatogenesis associated 7
STARD13 StAR-related lipid transfer (START) domain containing 13
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYT17 synaptotagmin XVII
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCEAL1 transcription elongation factor A (SII)-like 1
TESK2 testis-specific kinase 2
TMEM168 transmembrane protein 168
TRIM5 tripartite motif containing 5
VAMP4 vesicle-associated membrane protein 4
VAV3 vav 3 guanine nucleotide exchange factor
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
XYLT2 xylosyltransferase II
ZBTB25 zinc finger and BTB domain containing 25
ZBTB39 zinc finger and BTB domain containing 39
ZNF639 zinc finger protein 639