5140203-908 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the 5140203-908 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM17 ADAM metallopeptidase domain 17
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APP amyloid beta (A4) precursor protein
ATG12 autophagy related 12
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BTBD7 BTB (POZ) domain containing 7
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CFLAR CASP8 and FADD-like apoptosis regulator
CLDN15 claudin 15
CRELD1 cysteine-rich with EGF-like domains 1
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSNK1G1 casein kinase 1, gamma 1
CUL4B cullin 4B
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EDRF1 erythroid differentiation regulatory factor 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
EVA1B eva-1 homolog B (C. elegans)
FANCA Fanconi anemia, complementation group A
FBXO38 F-box protein 38
FNDC3A fibronectin type III domain containing 3A
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR21 G protein-coupled receptor 21
GPR27 G protein-coupled receptor 27
GRIP2 glutamate receptor interacting protein 2
GSTA4 glutathione S-transferase alpha 4
IFT74 intraflagellar transport 74
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL6ST interleukin 6 signal transducer
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KDM5A lysine (K)-specific demethylase 5A
KLHL24 kelch-like family member 24
LARP4B La ribonucleoprotein domain family, member 4B
LHX6 LIM homeobox 6
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
MAPK11 mitogen-activated protein kinase 11
MBTD1 mbt domain containing 1
MCL1 myeloid cell leukemia 1
MCM4 minichromosome maintenance complex component 4
MITF microphthalmia-associated transcription factor
MMP9 matrix metallopeptidase 9
MOCS1 molybdenum cofactor synthesis 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEBL nebulette
NFRKB nuclear factor related to kappaB binding protein
PBX2 pre-B-cell leukemia homeobox 2
PDCD2 programmed cell death 2
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLK4 polo-like kinase 4
POM121 POM121 transmembrane nucleoporin
PRDX2 peroxiredoxin 2
PRLR prolactin receptor
R3HCC1L R3H domain and coiled-coil containing 1-like
RASA2 RAS p21 protein activator 2
RASL11B RAS-like, family 11, member B
RNGTT RNA guanylyltransferase and 5'-phosphatase
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RRP1B ribosomal RNA processing 1B
SAP30 Sin3A-associated protein, 30kDa
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIM2 single-minded family bHLH transcription factor 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOS2 son of sevenless homolog 2 (Drosophila)
SSPN sarcospan
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
TM2D1 TM2 domain containing 1
TMPRSS3 transmembrane protease, serine 3
TP53I11 tumor protein p53 inducible protein 11
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL3 tubulin tyrosine ligase-like family member 3
UNC45A unc-45 homolog A (C. elegans)
VLDLR very low density lipoprotein receptor
WDR1 WD repeat domain 1
WWOX WW domain containing oxidoreductase
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZCCHC24 zinc finger, CCHC domain containing 24
ZMYM6 zinc finger, MYM-type 6
ZNF227 zinc finger protein 227

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGO1 argonaute RISC catalytic component 1
APLP1 amyloid beta (A4) precursor-like protein 1
BPHL biphenyl hydrolase-like (serine hydrolase)
CABIN1 calcineurin binding protein 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK20 cyclin-dependent kinase 20
CEP97 centrosomal protein 97kDa
CIC capicua transcriptional repressor
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CYB561D2 cytochrome b561 family, member D2
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EFCAB2 EF-hand calcium binding domain 2
EFHD2 EF-hand domain family, member D2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM134B family with sequence similarity 134, member B
FCHO1 FCH domain only 1
FMO4 flavin containing monooxygenase 4
FXR2 fragile X mental retardation, autosomal homolog 2
GPR153 G protein-coupled receptor 153
GPR87 G protein-coupled receptor 87
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
IFT22 intraflagellar transport 22
IPP intracisternal A particle-promoted polypeptide
KDM8 lysine (K)-specific demethylase 8
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KRT15 keratin 15, type I
KRT86 keratin 86, type II
LIME1 Lck interacting transmembrane adaptor 1
LOC100287590 uncharacterized LOC100287590
LOC642236 FSHD region gene 1 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP3 low density lipoprotein receptor-related protein 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAP1S microtubule-associated protein 1S
MATK megakaryocyte-associated tyrosine kinase
MEIS1 Meis homeobox 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPS18C mitochondrial ribosomal protein S18C
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
NAV2 neuron navigator 2
NPIPB15 nuclear pore complex interacting protein family, member B15
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PALM paralemmin
PLA2G3 phospholipase A2, group III
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMP22 peripheral myelin protein 22
PTK6 protein tyrosine kinase 6
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRU protein tyrosine phosphatase, receptor type, U
RAD54L RAD54-like (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM14 RNA binding motif protein 14
RBM42 RNA binding motif protein 42
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHOBTB2 Rho-related BTB domain containing 2
SCAMP4 secretory carrier membrane protein 4
SCML2 sex comb on midleg-like 2 (Drosophila)
SIDT1 SID1 transmembrane family, member 1
SLC12A9 solute carrier family 12, member 9
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SMA4 glucuronidase, beta pseudogene
SYCP2 synaptonemal complex protein 2
TARP TCR gamma alternate reading frame protein
TBC1D10B TBC1 domain family, member 10B
TEAD3 TEA domain family member 3
TIGD6 tigger transposable element derived 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMPRSS4 transmembrane protease, serine 4
TTC33 tetratricopeptide repeat domain 33
TTLL1 tubulin tyrosine ligase-like family member 1
USB1 U6 snRNA biogenesis 1
WWC2 WW and C2 domain containing 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF180 zinc finger protein 180
ZNF219 zinc finger protein 219
ZNF571 zinc finger protein 571
ZNF629 zinc finger protein 629
ZNF665 zinc finger protein 665
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862
ZSCAN31 zinc finger and SCAN domain containing 31