5114445-901 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the 5114445-901 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP9 A kinase (PRKA) anchor protein 9
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOM apolipoprotein M
ASTN2 astrotactin 2
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATXN3 ataxin 3
C19ORF66 chromosome 19 open reading frame 66
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCP110 centriolar coiled coil protein 110kDa
CD8A CD8a molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDON cell adhesion associated, oncogene regulated
CENPJ centromere protein J
CGA glycoprotein hormones, alpha polypeptide
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLEC10A C-type lectin domain family 10, member A
COL9A3 collagen, type IX, alpha 3
CSHL1 chorionic somatomammotropin hormone-like 1
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DST dystonin
EPOR erythropoietin receptor
FAM214B family with sequence similarity 214, member B
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
GID4 GID complex subunit 4
GLRA3 glycine receptor, alpha 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR37L1 G protein-coupled receptor 37 like 1
GSPT1 G1 to S phase transition 1
HIST1H2BN histone cluster 1, H2bn
HLA-E major histocompatibility complex, class I, E
HNF1B HNF1 homeobox B
HOXD13 homeobox D13
HSPB6 heat shock protein, alpha-crystallin-related, B6
IL1R2 interleukin 1 receptor, type II
INHBE inhibin, beta E
KCTD7 potassium channel tetramerization domain containing 7
KIAA1109 KIAA1109
KLHL24 kelch-like family member 24
KLHL25 kelch-like family member 25
KLK8 kallikrein-related peptidase 8
KSR1 kinase suppressor of ras 1
LIG3 ligase III, DNA, ATP-dependent
LUZP1 leucine zipper protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MED14 mediator complex subunit 14
MSL3 male-specific lethal 3 homolog (Drosophila)
NFRKB nuclear factor related to kappaB binding protein
NPHP4 nephronophthisis 4
NUMA1 nuclear mitotic apparatus protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
PCDH12 protocadherin 12
PDCD2 programmed cell death 2
PLK4 polo-like kinase 4
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKD3 protein kinase D3
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RASA3 RAS p21 protein activator 3
RHOBTB3 Rho-related BTB domain containing 3
RIMBP2 RIMS binding protein 2
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNDC3B RUN domain containing 3B
SCGB2A1 secretoglobin, family 2A, member 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SRD5A3 steroid 5 alpha-reductase 3
SRSF11 serine/arginine-rich splicing factor 11
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
SUGP1 SURP and G patch domain containing 1
SYP synaptophysin
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM212 transmembrane protein 212
TRAPPC9 trafficking protein particle complex 9
TRIO trio Rho guanine nucleotide exchange factor
TRO trophinin
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WIZ widely interspaced zinc finger motifs
ZNF419 zinc finger protein 419
ZNF783 zinc finger family member 783
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ALG6 ALG6, alpha-1,3-glucosyltransferase
ANKRD10 ankyrin repeat domain 10
ANKRD36B ankyrin repeat domain 36B
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
BBC3 BCL2 binding component 3
BBS10 Bardet-Biedl syndrome 10
BMP4 bone morphogenetic protein 4
C22ORF29 chromosome 22 open reading frame 29
CARD8 caspase recruitment domain family, member 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNO cyclin O
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFD complement factor D (adipsin)
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CTSK cathepsin K
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DSCAM Down syndrome cell adhesion molecule
EAF2 ELL associated factor 2
EFCAB2 EF-hand calcium binding domain 2
FAM193A family with sequence similarity 193, member A
FASTKD5 FAST kinase domains 5
FBXW12 F-box and WD repeat domain containing 12
FGGY FGGY carbohydrate kinase domain containing
FLT4 fms-related tyrosine kinase 4
FXN frataxin
GDAP1 ganglioside induced differentiation associated protein 1
GHR growth hormone receptor
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIRA histone cell cycle regulator
HSPA2 heat shock 70kDa protein 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RB interleukin 17 receptor B
INTS7 integrator complex subunit 7
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0125 KIAA0125
LIN7B lin-7 homolog B (C. elegans)
LINS lines homolog (Drosophila)
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MEPCE methylphosphate capping enzyme
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MSL1 male-specific lethal 1 homolog (Drosophila)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NR1H3 nuclear receptor subfamily 1, group H, member 3
OSMR oncostatin M receptor
OXTR oxytocin receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARPBP PARP1 binding protein
PDPK1 3-phosphoinositide dependent protein kinase 1
PGR progesterone receptor
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PISD phosphatidylserine decarboxylase
PLA2G15 phospholipase A2, group XV
POLR1B polymerase (RNA) I polypeptide B, 128kDa
RBM42 RNA binding motif protein 42
RHOBTB1 Rho-related BTB domain containing 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SETD6 SET domain containing 6
SLC12A8 solute carrier family 12, member 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SMAD5 SMAD family member 5
SOAT1 sterol O-acyltransferase 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYBU syntabulin (syntaxin-interacting)
TGFB3 transforming growth factor, beta 3
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM127 transmembrane protein 127
TMEM183A transmembrane protein 183A
TMEM2 transmembrane protein 2
TPCN1 two pore segment channel 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBQLN4 ubiquilin 4
UNKL unkempt family zinc finger-like
USB1 U6 snRNA biogenesis 1
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR60 WD repeat domain 60
WDR76 WD repeat domain 76
ZBED1 zinc finger, BED-type containing 1
ZNF276 zinc finger protein 276
ZNF654 zinc finger protein 654
ZNF675 zinc finger protein 675
ZNF721 zinc finger protein 721