5109870-904 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 5109870-904 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
AMPD3 adenosine monophosphate deaminase 3
ANGPTL4 angiopoietin-like 4
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ASTN2 astrotactin 2
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BIK BCL2-interacting killer (apoptosis-inducing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
CCNG2 cyclin G2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEL carboxyl ester lipase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DPYSL4 dihydropyrimidinase-like 4
DTNA dystrobrevin, alpha
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ENO2 enolase 2 (gamma, neuronal)
ERO1L ERO1-like (S. cerevisiae)
F8 coagulation factor VIII, procoagulant component
FADS3 fatty acid desaturase 3
FAM212B family with sequence similarity 212, member B
FAS Fas cell surface death receptor
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GBE1 glucan (1,4-alpha-), branching enzyme 1
GPR87 G protein-coupled receptor 87
GYS1 glycogen synthase 1 (muscle)
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HMOX1 heme oxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
INHBE inhibin, beta E
INSIG2 insulin induced gene 2
KDM3A lysine (K)-specific demethylase 3A
KDM4B lysine (K)-specific demethylase 4B
LHX6 LIM homeobox 6
LIF leukemia inhibitory factor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MR1 major histocompatibility complex, class I-related
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NFIL3 nuclear factor, interleukin 3 regulated
NUPR1 nuclear protein, transcriptional regulator, 1
ORAI3 ORAI calcium release-activated calcium modulator 3
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGM1 phosphoglucomutase 1
PLAUR plasminogen activator, urokinase receptor
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRR4 proline rich 4 (lacrimal)
PVT1 Pvt1 oncogene (non-protein coding)
RGS20 regulator of G-protein signaling 20
RNF19B ring finger protein 19B
SAV1 salvador family WW domain containing protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SESN1 sestrin 1
SFXN3 sideroflexin 3
SH2B2 SH2B adaptor protein 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SPAG4 sperm associated antigen 4
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STC1 stanniocalcin 1
SUSD6 sushi domain containing 6
TMEM45A transmembrane protein 45A
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TP53I3 tumor protein p53 inducible protein 3
TRA2A transformer 2 alpha homolog (Drosophila)
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
ZNF292 zinc finger protein 292
ZNF395 zinc finger protein 395
ZNF654 zinc finger protein 654
ZNF767P zinc finger family member 767, pseudogene

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD40 ankyrin repeat domain 40
ARHGAP19 Rho GTPase activating protein 19
ARMC7 armadillo repeat containing 7
ARMCX1 armadillo repeat containing, X-linked 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKB aurora kinase B
BAK1 BCL2-antagonist/killer 1
BMP4 bone morphogenetic protein 4
BORA bora, aurora kinase A activator
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CCNB1 cyclin B1
CCNE1 cyclin E1
CCNF cyclin F
CDC20 cell division cycle 20
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CEP97 centrosomal protein 97kDa
CIT citron rho-interacting serine/threonine kinase
CXCL12 chemokine (C-X-C motif) ligand 12
DEPDC1 DEP domain containing 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNALI1 dynein, axonemal, light intermediate chain 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOLK dolichol kinase
E2F8 E2F transcription factor 8
ELOVL4 ELOVL fatty acid elongase 4
FAM111A family with sequence similarity 111, member A
FAM64A family with sequence similarity 64, member A
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FZD2 frizzled class receptor 2
GTSE1 G-2 and S-phase expressed 1
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXC11 homeobox C11
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKB inositol-trisphosphate 3-kinase B
KIAA1551 KIAA1551
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF18A kinesin family member 18A
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
KIF4A kinesin family member 4A
KIFC1 kinesin family member C1
MKI67 marker of proliferation Ki-67
MTERF1 mitochondrial transcription termination factor 1
NCAPG non-SMC condensin I complex, subunit G
NCAPH non-SMC condensin I complex, subunit H
NDC80 NDC80 kinetochore complex component
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NMU neuromedin U
NPY1R neuropeptide Y receptor Y1
NUSAP1 nucleolar and spindle associated protein 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLK1 polo-like kinase 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PSRC1 proline/serine-rich coiled-coil 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RACGAP1 Rac GTPase activating protein 1
RBM42 RNA binding motif protein 42
REEP4 receptor accessory protein 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RNF25 ring finger protein 25
SALL2 spalt-like transcription factor 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SGK1 serum/glucocorticoid regulated kinase 1
SOBP sine oculis binding protein homolog (Drosophila)
SPC25 SPC25, NDC80 kinetochore complex component
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SUN2 Sad1 and UNC84 domain containing 2
SUOX sulfite oxidase
TACC3 transforming, acidic coiled-coil containing protein 3
TMEM104 transmembrane protein 104
TOP2A topoisomerase (DNA) II alpha 170kDa
TPX2 TPX2, microtubule-associated
TROAP trophinin associated protein
TTK TTK protein kinase
UBE2C ubiquitin-conjugating enzyme E2C
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF165 zinc finger protein 165
ZNF254 zinc finger protein 254
ZNF675 zinc finger protein 675
ZNF85 zinc finger protein 85
ZSCAN31 zinc finger and SCAN domain containing 31