4-hydroxyproline metabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls. (Gene Ontology, GO_0019471)
External Link http://amigo.geneontology.org/amigo/term/GO:0019471
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Genes

13 genes participating in the 4-hydroxyproline metabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
ERO1L ERO1-like (S. cerevisiae)
ERO1LB ERO1-like beta (S. cerevisiae)
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HB prolyl 4-hydroxylase, beta polypeptide
PRDX4 peroxiredoxin 4
PRODH proline dehydrogenase (oxidase) 1