4 iron, 4 sulfur cluster binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. (Gene Ontology, GO_0051539)
External Link http://amigo.geneontology.org/amigo/term/GO:0051539
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Genes

38 genes performing the 4 iron, 4 sulfur cluster binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ACO1 aconitase 1, soluble
ACO2 aconitase 2, mitochondrial
BRIP1 BRCA1 interacting protein C-terminal helicase 1
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DNA2 DNA replication helicase/nuclease 2
DPYD dihydropyrimidine dehydrogenase
ERCC2 excision repair cross-complementation group 2
ETFDH electron-transferring-flavoprotein dehydrogenase
EXO5 exonuclease 5
IREB2 iron-responsive element binding protein 2
LIAS lipoic acid synthetase
MOCS1 molybdenum cofactor synthesis 1
MUTYH mutY homolog
NARFL nuclear prelamin A recognition factor-like
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NFU1 NFU1 iron-sulfur cluster scaffold
NTHL1 nth endonuclease III-like 1 (E. coli)
NUBP1 nucleotide binding protein 1
NUBP2 nucleotide binding protein 2
NUBPL nucleotide binding protein-like
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPAT phosphoribosyl pyrophosphate amidotransferase
PRIM2 primase, DNA, polypeptide 2 (58kDa)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RSAD1 radical S-adenosyl methionine domain containing 1
RSAD2 radical S-adenosyl methionine domain containing 2
RTEL1 regulator of telomere elongation helicase 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)