4,5-dianilinophthalimide-624 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the 4,5-dianilinophthalimide-624 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACOT8 acyl-CoA thioesterase 8
ACOX1 acyl-CoA oxidase 1, palmitoyl
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANXA2P3 annexin A2 pseudogene 3
ARTN artemin
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASF1A anti-silencing function 1A histone chaperone
ATG4B autophagy related 4B, cysteine peptidase
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BBC3 BCL2 binding component 3
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRD1 bromodomain containing 1
BSDC1 BSD domain containing 1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CENPO centromere protein O
CNPY3 canopy FGF signaling regulator 3
COL6A2 collagen, type VI, alpha 2
DBF4B DBF4 zinc finger B
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDIT3 DNA-damage-inducible transcript 3
DLG5 discs, large homolog 5 (Drosophila)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DVL3 dishevelled segment polarity protein 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM192A family with sequence similarity 192, member A
FBXO42 F-box protein 42
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GATA2 GATA binding protein 2
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPC1 glypican 1
GRK6 G protein-coupled receptor kinase 6
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
HLA-G major histocompatibility complex, class I, G
HPS1 Hermansky-Pudlak syndrome 1
ICAM1 intercellular adhesion molecule 1
KDM4A lysine (K)-specific demethylase 4A
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
KRT6B keratin 6B, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1C myosin IC
N4BP2L1 NEDD4 binding protein 2-like 1
NIPAL2 NIPA-like domain containing 2
NKTR natural killer cell triggering receptor
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OGFR opioid growth factor receptor
PCSK7 proprotein convertase subtilisin/kexin type 7
PELP1 proline, glutamate and leucine rich protein 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLCD1 phospholipase C, delta 1
PLXND1 plexin D1
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTCRA pre T-cell antigen receptor alpha
RBBP5 retinoblastoma binding protein 5
RBBP6 retinoblastoma binding protein 6
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RXRA retinoid X receptor, alpha
SH2D3A SH2 domain containing 3A
SIRT5 sirtuin 5
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STK11 serine/threonine kinase 11
TFE3 transcription factor binding to IGHM enhancer 3
TMED9 transmembrane emp24 protein transport domain containing 9
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRAF4 TNF receptor-associated factor 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
WDR46 WD repeat domain 46
WDTC1 WD and tetratricopeptide repeats 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YIPF2 Yip1 domain family, member 2
ZBTB17 zinc finger and BTB domain containing 17
ZMYND8 zinc finger, MYND-type containing 8
ZNF335 zinc finger protein 335
ZNF444 zinc finger protein 444
ZNF592 zinc finger protein 592
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AMN amnion associated transmembrane protein
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANKRD40 ankyrin repeat domain 40
AP5M1 adaptor-related protein complex 5, mu 1 subunit
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATG2A autophagy related 2A
ATOX1 antioxidant 1 copper chaperone
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
BRD7 bromodomain containing 7
C2ORF49 chromosome 2 open reading frame 49
CALCOCO1 calcium binding and coiled-coil domain 1
CAMLG calcium modulating ligand
CBX4 chromobox homolog 4
CDC7 cell division cycle 7
CDC73 cell division cycle 73
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CIC capicua transcriptional repressor
CLEC16A C-type lectin domain family 16, member A
COQ6 coenzyme Q6 monooxygenase
CRYL1 crystallin, lambda 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DENR density-regulated protein
DGKD diacylglycerol kinase, delta 130kDa
DHDDS dehydrodolichyl diphosphate synthase
DPH2 DPH2 homolog (S. cerevisiae)
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ENAH enabled homolog (Drosophila)
EPHA2 EPH receptor A2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM193A family with sequence similarity 193, member A
FAM46A family with sequence similarity 46, member A
FAM57A family with sequence similarity 57, member A
FANCG Fanconi anemia, complementation group G
FBXL14 F-box and leucine-rich repeat protein 14
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GGNBP2 gametogenetin binding protein 2
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPHN gephyrin
GTF2H5 general transcription factor IIH, polypeptide 5
HACD1 3-hydroxyacyl-CoA dehydratase 1
HLA-DMB major histocompatibility complex, class II, DM beta
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IRX4 iroquois homeobox 4
ITPKC inositol-trisphosphate 3-kinase C
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD9 potassium channel tetramerization domain containing 9
KIF20B kinesin family member 20B
KLF3 Kruppel-like factor 3 (basic)
KRCC1 lysine-rich coiled-coil 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MAN2A1 mannosidase, alpha, class 2A, member 1
MEIS3P1 Meis homeobox 3 pseudogene 1
MGP matrix Gla protein
NPY1R neuropeptide Y receptor Y1
OAT ornithine aminotransferase
PCNP PEST proteolytic signal containing nuclear protein
PHLDA2 pleckstrin homology-like domain, family A, member 2
POU2F1 POU class 2 homeobox 1
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RBM14 RNA binding motif protein 14
RBM15B RNA binding motif protein 15B
RBM6 RNA binding motif protein 6
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RNF111 ring finger protein 111
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCML2 sex comb on midleg-like 2 (Drosophila)
SESN1 sestrin 1
SHPK sedoheptulokinase
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
TBCC tubulin folding cofactor C
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TGFBI transforming growth factor, beta-induced, 68kDa
TLN1 talin 1
TMEM123 transmembrane protein 123
TOE1 target of EGR1, member 1 (nuclear)
TOR1B torsin family 1, member B (torsin B)
TPCN1 two pore segment channel 1
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSPYL4 TSPY-like 4
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UNKL unkempt family zinc finger-like
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
USP8 ubiquitin specific peptidase 8
WDR44 WD repeat domain 44
YBX2 Y box binding protein 2
ZBTB22 zinc finger and BTB domain containing 22
ZC3H7A zinc finger CCCH-type containing 7A
ZNF195 zinc finger protein 195