253JBV Gene Set

Dataset CCLE Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Highly metastatic variant from human transitional cell carcinoma. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004894)
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Genes

365 genes with high or low expression in 253JBV relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
MORC4 MORC family CW-type zinc finger 4 2.82603
GPR52 G protein-coupled receptor 52 2.80781
RBM43 RNA binding motif protein 43 2.72535
RAD21L1 RAD21-like 1 (S. pombe) 2.65492
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 2.65458
RFK riboflavin kinase 2.53501
LOC388780 uncharacterized LOC388780 2.48041
CREB5 cAMP responsive element binding protein 5 2.47836
ARHGAP26 Rho GTPase activating protein 26 2.47836
RFPL2 ret finger protein-like 2 2.47177
BTC betacellulin 2.39919
ANKRD7 ankyrin repeat domain 7 2.33731
BCL10 B-cell CLL/lymphoma 10 2.27862
SSH2 slingshot protein phosphatase 2 2.25695
DAW1 dynein assembly factor with WDR repeat domains 1 2.22813
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 2.22587
NRG1 neuregulin 1 2.2116
ANKRD31 ankyrin repeat domain 31 2.20274
TTC29 tetratricopeptide repeat domain 29 2.18872
C3ORF67 chromosome 3 open reading frame 67 2.16339
TTLL6 tubulin tyrosine ligase-like family member 6 2.15226
LOC401317 uncharacterized LOC401317 2.13434
LOC284395 uncharacterized LOC284395 2.12583
IAPP islet amyloid polypeptide 2.11323
LOC284080 uncharacterized LOC284080 2.10305
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.09564
MRPL33 mitochondrial ribosomal protein L33 2.08688
THOC2 THO complex 2 2.08083
NSFL1C NSFL1 (p97) cofactor (p47) 2.0769
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 2.0504
LPPR5 lipid phosphate phosphatase-related protein type 5 2.03583
CST11 cystatin 11 1.99789
DYX1C1 dyslexia susceptibility 1 candidate 1 1.99143
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 1.98867
NLGN1 neuroligin 1 1.98487
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 1.97386
RPL32P3 ribosomal protein L32 pseudogene 3 1.9608
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 1.94675
LOC100129620 uncharacterized LOC100129620 1.93676
CDC14C cell division cycle 14C 1.92577
LOC100506498 uncharacterized LOC100506498 1.90809
BCO2 beta-carotene oxygenase 2 1.87787
MRPS9 mitochondrial ribosomal protein S9 1.87617
CUL2 cullin 2 1.87482
TINAG tubulointerstitial nephritis antigen 1.86726
ZNHIT6 zinc finger, HIT-type containing 6 1.84761
GDA guanine deaminase 1.84683
C1ORF52 chromosome 1 open reading frame 52 1.83177
WBSCR28 Williams-Beuren syndrome chromosome region 28 1.82917
CHAD chondroadherin 1.82035
LUZP4 leucine zipper protein 4 1.81348
KNCN kinocilin 1.80848
CDKN2B-AS1 CDKN2B antisense RNA 1 1.8062
TXNRD1 thioredoxin reductase 1 1.80533
PDE1A phosphodiesterase 1A, calmodulin-dependent 1.79973
AAGAB alpha- and gamma-adaptin binding protein 1.7969
LOC284788 uncharacterized LOC284788 1.79668
RBKS ribokinase 1.79471
RDH10 retinol dehydrogenase 10 (all-trans) 1.79176
C6ORF58 chromosome 6 open reading frame 58 1.78885
ZXDA zinc finger, X-linked, duplicated A 1.78159
FGD1 FYVE, RhoGEF and PH domain containing 1 1.78023
CIB1 calcium and integrin binding 1 (calmyrin) 1.77946
FBXO22 F-box protein 22 1.7742
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 1.77275
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 1.76776
NIFK nucleolar protein interacting with the FHA domain of MKI67 1.76376
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 1.75452
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 1.75403
HLF hepatic leukemia factor 1.74622
SHISA2 shisa family member 2 1.74115
DTD1 D-tyrosyl-tRNA deacylase 1 1.73871
CRYZ crystallin, zeta (quinone reductase) 1.73555
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.72789
LONRF2 LON peptidase N-terminal domain and ring finger 2 1.72705
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 1.72681
DOCK4 dedicator of cytokinesis 4 1.70499
HOXA4 homeobox A4 1.70444
NUP62CL nucleoporin 62kDa C-terminal like 1.70038
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 1.69811
TCEAL8 transcription elongation factor A (SII)-like 8 1.69624
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 1.68622
FBXL21 F-box and leucine-rich repeat protein 21 (gene/pseudogene) 1.68313
ARMC10 armadillo repeat containing 10 1.67614
RYR3 ryanodine receptor 3 1.67357
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 1.66955
TTC25 tetratricopeptide repeat domain 25 1.66888
TM4SF18 transmembrane 4 L six family member 18 1.66017
RIPK2 receptor-interacting serine-threonine kinase 2 1.6585
RPS6 ribosomal protein S6 1.65472
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 1.63824
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.63687
LOC100422737 uncharacterized LOC100422737 1.63486
LECT2 leukocyte cell-derived chemotaxin 2 1.63451
LOC729506 uncharacterized LOC729506 1.63337
IQUB IQ motif and ubiquitin domain containing 1.62757
LRRC73 leucine rich repeat containing 73 1.62656
SHROOM4 shroom family member 4 1.6228
CCNO cyclin O 1.62195
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.6186
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 1.61773
GRIA4 glutamate receptor, ionotropic, AMPA 4 1.61745
C2CD4A C2 calcium-dependent domain containing 4A 1.61674
NUAK2 NUAK family, SNF1-like kinase, 2 1.61226
FAM155B family with sequence similarity 155, member B 1.61206
VCAM1 vascular cell adhesion molecule 1 1.60931
C4ORF36 chromosome 4 open reading frame 36 1.60426
KCNK3 potassium channel, two pore domain subfamily K, member 3 1.60231
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 1.59671
RGS22 regulator of G-protein signaling 22 1.58406
DNM1 dynamin 1 1.57898
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 1.5784
HCG4B HLA complex group 4B (non-protein coding) 1.57262
LOC283914 1.56703
CCL8 chemokine (C-C motif) ligand 8 1.56412
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 1.5641
APOF apolipoprotein F 1.55605
CCM2L cerebral cavernous malformation 2-like 1.55302
ZNF485 zinc finger protein 485 1.55194
LINC00477 long intergenic non-protein coding RNA 477 1.54865
ASCC1 activating signal cointegrator 1 complex subunit 1 1.54809
RGS5 regulator of G-protein signaling 5 1.54524
PLK2 polo-like kinase 2 1.53712
SYCP1 synaptonemal complex protein 1 1.53606
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 1.52666
EFHB EF-hand domain family, member B 1.51944
DSTNP2 destrin (actin depolymerizing factor) pseudogene 2 1.51823
DUSP5 dual specificity phosphatase 5 1.51761
ISCU iron-sulfur cluster assembly enzyme 1.51734
C2ORF82 chromosome 2 open reading frame 82 1.51709
CRISP1 cysteine-rich secretory protein 1 1.50534
BUD31 BUD31 homolog (S. cerevisiae) 1.50427
RIPPLY1 ripply transcriptional repressor 1 1.5002
PCSK5 proprotein convertase subtilisin/kexin type 5 1.49975
WWTR1 WW domain containing transcription regulator 1 1.49911
CLDN16 claudin 16 1.49656
MAGEB6 melanoma antigen family B6 1.49444
KSR2 kinase suppressor of ras 2 1.4912
SETD4 SET domain containing 4 1.48936
SCIN scinderin 1.48883
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 1.48652
DZANK1 double zinc ribbon and ankyrin repeat domains 1 1.48421
MALSU1 mitochondrial assembly of ribosomal large subunit 1 1.48399
CXORF38 chromosome X open reading frame 38 1.48282
PDZK1IP1 PDZK1 interacting protein 1 1.47919
C6 complement component 6 1.47839
PAX2 paired box 2 1.47739
VGLL2 vestigial-like family member 2 1.47485
IQCD IQ motif containing D 1.47403
FAM81A family with sequence similarity 81, member A 1.46627
TAAR9 trace amine associated receptor 9 (gene/pseudogene) 1.46057
BBS4 Bardet-Biedl syndrome 4 1.45544
NOM1 nucleolar protein with MIF4G domain 1 1.45504
TRAV40 T cell receptor alpha variable 40 1.4547
PHEX phosphate regulating endopeptidase homolog, X-linked 1.45464
SPP1 secreted phosphoprotein 1 1.45284
KRTAP9-4 keratin associated protein 9-4 1.45189
PRPF38B pre-mRNA processing factor 38B 1.45108
KIF5A kinesin family member 5A 1.44854
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 1.446
ZNF630 zinc finger protein 630 1.44427
RASGEF1C RasGEF domain family, member 1C 1.44385
FIGN fidgetin 1.44354
SELO selenoprotein O 1.43978
DYDC2 DPY30 domain containing 2 1.43917
NCS1 neuronal calcium sensor 1 1.4378
PSPH phosphoserine phosphatase 1.43617
CORO6 coronin 6 1.43615
FLJ31104 uncharacterized LOC441072 1.43578
C14ORF105 chromosome 14 open reading frame 105 1.43149
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 1.42829
CRH corticotropin releasing hormone 1.42661
SLMAP sarcolemma associated protein 1.42532
LOC100505870 uncharacterized LOC100505870 1.42421
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 1.41894
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 1.41893
KRT2 keratin 2, type II 1.41836
CAAP1 caspase activity and apoptosis inhibitor 1 1.41728
PISD phosphatidylserine decarboxylase 1.41307
NCBP2 nuclear cap binding protein subunit 2, 20kDa 1.40533
RILP Rab interacting lysosomal protein 1.4014
PARG poly (ADP-ribose) glycohydrolase 1.40084
NOTCH2 notch 2 1.39975
IRAK2 interleukin-1 receptor-associated kinase 2 1.39779
LOC100506530 uncharacterized LOC100506530 1.39714
FLJ45513 uncharacterized LOC729220 1.39489
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.39467
C10ORF95 chromosome 10 open reading frame 95 1.39457
TNIK TRAF2 and NCK interacting kinase 1.39287
NTPCR nucleoside-triphosphatase, cancer-related 1.39198
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 1.39192
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 1.39066
MMP7 matrix metallopeptidase 7 1.38713
PTGES3 prostaglandin E synthase 3 (cytosolic) 1.37761
NBN nibrin 1.37743
NKAP NFKB activating protein 1.37174
KLF10 Kruppel-like factor 10 1.37122
BTN1A1 butyrophilin, subfamily 1, member A1 1.37116
DMGDH dimethylglycine dehydrogenase 1.37002
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 1.36998
LOC283585 uncharacterized LOC283585 1.36842
NCEH1 neutral cholesterol ester hydrolase 1 1.36747
PROCR protein C receptor, endothelial 1.36701
CXORF58 chromosome X open reading frame 58 1.36334
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.3628
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) 1.35977
DHRS4-AS1 DHRS4 antisense RNA 1 1.35911
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.35391
USP26 ubiquitin specific peptidase 26 1.35325
EGLN1 egl-9 family hypoxia-inducible factor 1 1.35161
IFNA5 interferon, alpha 5 1.3507
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 1.35
UCN urocortin 1.34863
CFAP47 cilia and flagella associated protein 47 1.1401

low expression

Symbol Name Standardized Value
C6ORF106 chromosome 6 open reading frame 106 -3.44648
FXR1 fragile X mental retardation, autosomal homolog 1 -3.00897
ADD1 adducin 1 (alpha) -2.87278
NUMA1 nuclear mitotic apparatus protein 1 -2.8304
OBP2A odorant binding protein 2A -2.74822
SETD2 SET domain containing 2 -2.7179
CAPN7 calpain 7 -2.55986
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -2.44573
SUMO3 small ubiquitin-like modifier 3 -2.37742
MCOLN1 mucolipin 1 -2.37687
NXF1 nuclear RNA export factor 1 -2.34349
USF2 upstream transcription factor 2, c-fos interacting -2.21408
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -2.20509
QDPR quinoid dihydropteridine reductase -2.19297
MBD3 methyl-CpG binding domain protein 3 -2.19094
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 -2.18301
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -2.13812
NSD1 nuclear receptor binding SET domain protein 1 -2.12332
MAPK14 mitogen-activated protein kinase 14 -2.1054
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding) -2.08118
CLPTM1 cleft lip and palate associated transmembrane protein 1 -2.07664
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) -2.06432
CTPS2 CTP synthase 2 -2.06418
REEP2 receptor accessory protein 2 -2.04854
PNRC2 proline-rich nuclear receptor coactivator 2 -2.04755
WNT7A wingless-type MMTV integration site family, member 7A -2.03452
SPAG5 sperm associated antigen 5 -2.03375
EVI5L ecotropic viral integration site 5-like -2.02897
IGSF6 immunoglobulin superfamily, member 6 -2.02343
YIPF1 Yip1 domain family, member 1 -1.996
MAPK15 mitogen-activated protein kinase 15 -1.97934
ZNF324 zinc finger protein 324 -1.97892
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -1.97526
ZFPL1 zinc finger protein-like 1 -1.97406
MOB2 MOB kinase activator 2 -1.9724
TMEM57 transmembrane protein 57 -1.97125
C1ORF233 chromosome 1 open reading frame 233 -1.96164
KAT5 K(lysine) acetyltransferase 5 -1.94844
MAP2K7 mitogen-activated protein kinase kinase 7 -1.94083
RAB3A RAB3A, member RAS oncogene family -1.92966
ZNF333 zinc finger protein 333 -1.92372
PRR9 proline rich 9 -1.91648
ZNF266 zinc finger protein 266 -1.91273
BAG6 BCL2-associated athanogene 6 -1.89054
HAP1 huntingtin-associated protein 1 -1.88679
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y -1.86963
CDYL chromodomain protein, Y-like -1.86719
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -1.85683
IL36A interleukin 36, alpha -1.85127
ZBTB1 zinc finger and BTB domain containing 1 -1.83619
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit -1.82793
TOX4 TOX high mobility group box family member 4 -1.81834
FOXO3 forkhead box O3 -1.8097
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -1.80926
KIAA2013 KIAA2013 -1.80886
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit -1.80705
WDR6 WD repeat domain 6 -1.80218
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -1.80008
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -1.79908
MEG3 maternally expressed 3 (non-protein coding) -1.79312
EXOC3L4 exocyst complex component 3-like 4 -1.78293
MFSD10 major facilitator superfamily domain containing 10 -1.76667
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -1.76098
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -1.76001
HAMP hepcidin antimicrobial peptide -1.75796
ZNF551 zinc finger protein 551 -1.7544
ZBTB17 zinc finger and BTB domain containing 17 -1.75405
RIT2 Ras-like without CAAX 2 -1.75358
UBE3C ubiquitin protein ligase E3C -1.75087
C2ORF72 chromosome 2 open reading frame 72 -1.74417
LOC100130458 uncharacterized LOC100130458 -1.73758
KLHDC3 kelch domain containing 3 -1.7359
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -1.73587
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B -1.73272
MARCKSL1 MARCKS-like 1 -1.73077
RING1 ring finger protein 1 -1.72791
PKNOX1 PBX/knotted 1 homeobox 1 -1.72544
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3 -1.72042
CLDN9 claudin 9 -1.71967
RAB1B RAB1B, member RAS oncogene family -1.71372
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -1.70734
SPATA16 spermatogenesis associated 16 -1.69588
TBCB tubulin folding cofactor B -1.68859
FAAH fatty acid amide hydrolase -1.68715
PNKP polynucleotide kinase 3'-phosphatase -1.68
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -1.67931
ZNF419 zinc finger protein 419 -1.67872
ZBTB49 zinc finger and BTB domain containing 49 -1.6684
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -1.65469
ZNF211 zinc finger protein 211 -1.65188
ABHD12 abhydrolase domain containing 12 -1.64873
PLD3 phospholipase D family, member 3 -1.64793
RNF146 ring finger protein 146 -1.64397
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -1.63113
TMEM59 transmembrane protein 59 -1.62465
NR2F6 nuclear receptor subfamily 2, group F, member 6 -1.62456
RAB6A RAB6A, member RAS oncogene family -1.62388
CES1P1 carboxylesterase 1 pseudogene 1 -1.61894
NT5C1A 5'-nucleotidase, cytosolic IA -1.6122
LINC00029 long intergenic non-protein coding RNA 29 -1.60602
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 -1.60541
TMEM259 transmembrane protein 259 -1.60464
ITFG2 integrin alpha FG-GAP repeat containing 2 -1.59675
DAAM1 dishevelled associated activator of morphogenesis 1 -1.59448
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -1.58997
IGHV3-9 immunoglobulin heavy variable 3-9 -1.58682
ZNF777 zinc finger protein 777 -1.58616
ISOC2 isochorismatase domain containing 2 -1.58566
IGSF8 immunoglobulin superfamily, member 8 -1.58327
TREM1 triggering receptor expressed on myeloid cells 1 -1.57916
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -1.57459
RHCE Rh blood group, CcEe antigens -1.57241
GLTSCR1 glioma tumor suppressor candidate region gene 1 -1.5688
CILP2 cartilage intermediate layer protein 2 -1.56824
CHKA choline kinase alpha -1.56456
DGCR2 DiGeorge syndrome critical region gene 2 -1.55915
ZNF496 zinc finger protein 496 -1.55792
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -1.55419
AKAP8L A kinase (PRKA) anchor protein 8-like -1.55246
IDNK idnK, gluconokinase homolog (E. coli) -1.54266
ZFYVE1 zinc finger, FYVE domain containing 1 -1.54075
PODXL2 podocalyxin-like 2 -1.54028
RASL10B RAS-like, family 10, member B -1.53703
ZNF548 zinc finger protein 548 -1.52996
FKRP fukutin related protein -1.52497
TPGS1 tubulin polyglutamylase complex subunit 1 -1.52393
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 -1.52158
LOC100288123 uncharacterized LOC100288123 -1.51638
COPA coatomer protein complex, subunit alpha -1.51359
UVRAG UV radiation resistance associated -1.51327
NCDN neurochondrin -1.50314
PARD3B par-3 family cell polarity regulator beta -1.50278
MED12 mediator complex subunit 12 -1.50135
MAN1A2 mannosidase, alpha, class 1A, member 2 -1.5006
LMBRD1 LMBR1 domain containing 1 -1.49944
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -1.49423
MUT methylmalonyl CoA mutase -1.48833
HTT huntingtin -1.48799
GORASP2 golgi reassembly stacking protein 2, 55kDa -1.48736
UROC1 urocanate hydratase 1 -1.48655
GLG1 golgi glycoprotein 1 -1.48255
GANAB glucosidase, alpha; neutral AB -1.48154
GORASP1 golgi reassembly stacking protein 1, 65kDa -1.47418
CPEB4 cytoplasmic polyadenylation element binding protein 4 -1.47321
NMB neuromedin B -1.47232
FAM193A family with sequence similarity 193, member A -1.4713
EXOSC6 exosome component 6 -1.46678
SZT2 seizure threshold 2 homolog (mouse) -1.46203
ZMYND10 zinc finger, MYND-type containing 10 -1.45504
ZBTB32 zinc finger and BTB domain containing 32 -1.45446
TPM4 tropomyosin 4 -1.45267