2313287 Gene Set

Dataset CCLE Cell Line Gene Mutation Profiles
Category genomics
Type cell line
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Genes

326 genes mutated in the 2313287 cell line from the CCLE Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACVR1B activin A receptor, type IB
ACVR1C activin A receptor, type IC
ACVR2B activin A receptor, type IIB
ADAM12 ADAM metallopeptidase domain 12
ADAM18 ADAM metallopeptidase domain 18
ADAM28 ADAM metallopeptidase domain 28
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADGRB1 adhesion G protein-coupled receptor B1
ADGRG4 adhesion G protein-coupled receptor G4
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP12 A kinase (PRKA) anchor protein 12
AKAP9 A kinase (PRKA) anchor protein 9
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALPK2 alpha-kinase 2
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANKK1 ankyrin repeat and kinase domain containing 1
ARHGAP29 Rho GTPase activating protein 29
ARID1A AT rich interactive domain 1A (SWI-like)
ASPH aspartate beta-hydroxylase
ATR ATR serine/threonine kinase
AXIN2 axin 2
BCL9 B-cell CLL/lymphoma 9
BIRC6 baculoviral IAP repeat containing 6
BLM Bloom syndrome, RecQ helicase-like
BMP4 bone morphogenetic protein 4
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRD2 bromodomain containing 2
BRD4 bromodomain containing 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTG1 B-cell translocation gene 1, anti-proliferative
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CARD11 caspase recruitment domain family, member 11
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNA1 cyclin A1
CCNB1 cyclin B1
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CCND2 cyclin D2
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK11B cyclin-dependent kinase 11B
CDK14 cyclin-dependent kinase 14
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK8 cyclin-dependent kinase 8
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHD8 chromodomain helicase DNA binding protein 8
CHEK2 checkpoint kinase 2
CHL1 cell adhesion molecule L1-like
CHN1 chimerin 1
CIC capicua transcriptional repressor
CIT citron rho-interacting serine/threonine kinase
CLK1 CDC-like kinase 1
CLTCL1 clathrin, heavy chain-like 1
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNTN6 contactin 6
CNTRL centriolin
CSF1R colony stimulating factor 1 receptor
CSMD3 CUB and Sushi multiple domains 3
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1G3 casein kinase 1, gamma 3
CSPG4 chondroitin sulfate proteoglycan 4
CTNNA2 catenin (cadherin-associated protein), alpha 2
CUBN cubilin (intrinsic factor-cobalamin receptor)
DAPK2 death-associated protein kinase 2
DCLK1 doublecortin-like kinase 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DFNA5 deafness, autosomal dominant 5
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAH8 dynein, axonemal, heavy chain 8
DOCK3 dedicator of cytokinesis 3
DST dystonin
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDN1 endothelin 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EML4 echinoderm microtubule associated protein like 4
EPHA3 EPH receptor A3
EPHA6 EPH receptor A6
EPHA7 EPH receptor A7
ERBB4 erb-b2 receptor tyrosine kinase 4
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ESR1 estrogen receptor 1
ETV1 ets variant 1
EXT1 exostosin glycosyltransferase 1
F12 coagulation factor XII (Hageman factor)
FANCE Fanconi anemia, complementation group E
FBN1 fibrillin 1
FBN2 fibrillin 2
FGF20 fibroblast growth factor 20
FGFR2 fibroblast growth factor receptor 2
FIP1L1 factor interacting with PAPOLA and CPSF1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLNA filamin A, alpha
FLNB filamin B, beta
FLNC filamin C, gamma
FN1 fibronectin 1
FNBP1 formin binding protein 1
FNTA farnesyltransferase, CAAX box, alpha
FOXP1 forkhead box P1
FRS2 fibroblast growth factor receptor substrate 2
FZD1 frizzled class receptor 1
GAS7 growth arrest-specific 7
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPC3 glypican 3
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GUCY2C guanylate cyclase 2C
HAPLN1 hyaluronan and proteoglycan link protein 1
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HDAC6 histone deacetylase 6
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNF1A HNF1 homeobox A
HOXD10 homeobox D10
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPB8 heat shock 22kDa protein 8
IKZF3 IKAROS family zinc finger 3 (Aiolos)
ILK integrin-linked kinase
IRS1 insulin receptor substrate 1
ITGA7 integrin, alpha 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAG1 jagged 1
JARID2 jumonji, AT rich interactive domain 2
KIAA1549 KIAA1549
KLK7 kallikrein-related peptidase 7
KMT2A lysine (K)-specific methyltransferase 2A
KMT2C lysine (K)-specific methyltransferase 2C
KPNA5 karyopherin alpha 5 (importin alpha 6)
KSR2 kinase suppressor of ras 2
KTN1 kinectin 1 (kinesin receptor)
LAMP1 lysosomal-associated membrane protein 1
LATS2 large tumor suppressor kinase 2
LNX2 ligand of numb-protein X 2
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
LRP6 low density lipoprotein receptor-related protein 6
LRRC2 leucine rich repeat containing 2
LRRK2 leucine-rich repeat kinase 2
LTK leukocyte receptor tyrosine kinase
MAML3 mastermind-like 3 (Drosophila)
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K19 mitogen-activated protein kinase kinase kinase 19
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK14 mitogen-activated protein kinase 14
MAST1 microtubule associated serine/threonine kinase 1
MAST4 microtubule associated serine/threonine kinase family member 4
MASTL microtubule associated serine/threonine kinase-like
MCF2 MCF.2 cell line derived transforming sequence
MCM3AP minichromosome maintenance complex component 3 associated protein
MGA MGA, MAX dimerization protein
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
MTMR11 myotubularin related protein 11
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTUS2 microtubule associated tumor suppressor candidate 2
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
N4BP2 NEDD4 binding protein 2
NCAM1 neural cell adhesion molecule 1
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NEK3 NIMA-related kinase 3
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFIA nuclear factor I/A
NGFR nerve growth factor receptor
NIPBL Nipped-B homolog (Drosophila)
NLK nemo-like kinase
NOTCH1 notch 1
NOTCH4 notch 4
NOVA1 neuro-oncological ventral antigen 1
NPAP1 nuclear pore associated protein 1
NPR1 natriuretic peptide receptor 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRK Nik related kinase
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP214 nucleoporin 214kDa
NUTM1 NUT midline carcinoma, family member 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
P4HB prolyl 4-hydroxylase, beta polypeptide
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAX3 paired box 3
PAX5 paired box 5
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCDH15 protocadherin-related 15
PCM1 pericentriolar material 1
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDIK1L PDLIM1 interacting kinase 1 like
PGR progesterone receptor
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLK2 polo-like kinase 2
PML promyelocytic leukemia
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
POMK protein-O-mannose kinase
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRCC papillary renal cell carcinoma (translocation-associated)
PRKCA protein kinase C, alpha
PRKCH protein kinase C, eta
PRKD3 protein kinase D3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG2 protein kinase, cGMP-dependent, type II
PSIP1 PC4 and SFRS1 interacting protein 1
PTEN phosphatase and tensin homolog
PTK7 protein tyrosine kinase 7 (inactive)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRU protein tyrosine phosphatase, receptor type, U
RAD50 RAD50 homolog (S. cerevisiae)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBBP8 retinoblastoma binding protein 8
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RHPN2 rhophilin, Rho GTPase binding protein 2
RIMS2 regulating synaptic membrane exocytosis 2
RIPK3 receptor-interacting serine-threonine kinase 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPL22 ribosomal protein L22
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPTOR regulatory associated protein of MTOR, complex 1
SACS sacsin molecular chaperone
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SGK2 serum/glucocorticoid regulated kinase 2
SGK223 homolog of rat pragma of Rnd2
SIRT1 sirtuin 1
SIX4 SIX homeobox 4
SMAD2 SMAD family member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOS1 son of sevenless homolog 1 (Drosophila)
SPEG SPEG complex locus
SPEN spen family transcriptional repressor
SPTAN1 spectrin, alpha, non-erythrocytic 1
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
STAG3 stromal antigen 3
STAT5A signal transducer and activator of transcription 5A
STK11 serine/threonine kinase 11
STK24 serine/threonine kinase 24
STK31 serine/threonine kinase 31
STK35 serine/threonine kinase 35
STRN4 striatin, calmodulin binding protein 4
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TAOK2 TAO kinase 2
TCF3 transcription factor 3
TESK2 testis-specific kinase 2
TG thyroglobulin
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLK1 tousled-like kinase 1
TLN1 talin 1
TLR3 toll-like receptor 3
TNIK TRAF2 and NCK interacting kinase
TNK1 tyrosine kinase, non-receptor, 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOX3 TOX high mobility group box family member 3
TP53BP1 tumor protein p53 binding protein 1
TP53RK TP53 regulating kinase
TP63 tumor protein p63
TP73 tumor protein p73
TRIB2 tribbles pseudokinase 2
TRIM24 tripartite motif containing 24
TRIM33 tripartite motif containing 33
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPS1 trichorhinophalangeal syndrome I
TRRAP transformation/transcription domain-associated protein
TSC1 tuberous sclerosis 1
TSSK1B testis-specific serine kinase 1B
TSSK3 testis-specific serine kinase 3
TTK TTK protein kinase
TTN titin
TWF1 twinfilin actin binding protein 1
UNC79 unc-79 homolog (C. elegans)
VEGFC vascular endothelial growth factor C
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WDHD1 WD repeat and HMG-box DNA binding protein 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WLS wntless Wnt ligand secretion mediator
WNK1 WNK lysine deficient protein kinase 1
WNK4 WNK lysine deficient protein kinase 4
WNT1 wingless-type MMTV integration site family, member 1
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
ZBTB16 zinc finger and BTB domain containing 16
ZNF217 zinc finger protein 217
ZNF331 zinc finger protein 331
ZNF423 zinc finger protein 423
ZNF608 zinc finger protein 608