2-deoxy-D-glucose-344 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 2-deoxy-D-glucose-344 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AHI1 Abelson helper integration site 1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ANKRD40 ankyrin repeat domain 40
AREG amphiregulin
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATG13 autophagy related 13
ATXN1 ataxin 1
BAIAP2 BAI1-associated protein 2
BCLAF1 BCL2-associated transcription factor 1
BET1 Bet1 golgi vesicular membrane trafficking protein
BRAP BRCA1 associated protein
C10ORF88 chromosome 10 open reading frame 88
C1ORF159 chromosome 1 open reading frame 159
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC7 coiled-coil domain containing 7
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHERP calcium homeostasis endoplasmic reticulum protein
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COG5 component of oligomeric golgi complex 5
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
DBR1 debranching RNA lariats 1
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP10 dual specificity phosphatase 10
DXO decapping exoribonuclease
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ERCC4 excision repair cross-complementation group 4
FERMT2 fermitin family member 2
FNDC3A fibronectin type III domain containing 3A
FOSL2 FOS-like antigen 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GPR87 G protein-coupled receptor 87
GRIK5 glutamate receptor, ionotropic, kainate 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HINFP histone H4 transcription factor
HMGN4 high mobility group nucleosomal binding domain 4
HPS1 Hermansky-Pudlak syndrome 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HUS1 HUS1 checkpoint homolog (S. pombe)
IL15RA interleukin 15 receptor, alpha
JOSD1 Josephin domain containing 1
JUN jun proto-oncogene
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KLF10 Kruppel-like factor 10
LUZP4 leucine zipper protein 4
MARS methionyl-tRNA synthetase
MBNL2 muscleblind-like splicing regulator 2
MEX3C mex-3 RNA binding family member C
MIS12 MIS12 kinetochore complex component
MNT MAX network transcriptional repressor
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MZF1 myeloid zinc finger 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIL3 nuclear factor, interleukin 3 regulated
NUCB1 nucleobindin 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARVA parvin, alpha
PCGF1 polycomb group ring finger 1
PRDM14 PR domain containing 14
PSPH phosphoserine phosphatase
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RBL2 retinoblastoma-like 2
RPS2 ribosomal protein S2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC23B Sec23 homolog B (S. cerevisiae)
SEC24D SEC24 family member D
SERP1 stress-associated endoplasmic reticulum protein 1
SH3BP2 SH3-domain binding protein 2
SIL1 SIL1 nucleotide exchange factor
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMC5 structural maintenance of chromosomes 5
SON SON DNA binding protein
SPAG11A sperm associated antigen 11A
SSUH2 ssu-2 homolog (C. elegans)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TGFB2 transforming growth factor, beta 2
TMED7 transmembrane emp24 protein transport domain containing 7
TRIM2 tripartite motif containing 2
TRIO trio Rho guanine nucleotide exchange factor
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
TXNL4A thioredoxin-like 4A
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACOT13 acyl-CoA thioesterase 13
ACSF2 acyl-CoA synthetase family member 2
AGMAT agmatine ureohydrolase (agmatinase)
ARSF arylsulfatase F
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BTBD2 BTB (POZ) domain containing 2
BTN1A1 butyrophilin, subfamily 1, member A1
C16ORF59 chromosome 16 open reading frame 59
C17ORF80 chromosome 17 open reading frame 80
C20ORF195 chromosome 20 open reading frame 195
CA7 carbonic anhydrase VII
CBR1 carbonyl reductase 1
CBX8 chromobox homolog 8
CCNE1 cyclin E1
CFAP70 cilia and flagella associated protein 70
CLCA1 chloride channel accessory 1
CORO1A coronin, actin binding protein, 1A
CPTP ceramide-1-phosphate transfer protein
CRYGB crystallin, gamma B
CRYM crystallin, mu
CTNNBIP1 catenin, beta interacting protein 1
DCLRE1A DNA cross-link repair 1A
DGAT1 diacylglycerol O-acyltransferase 1
DOLK dolichol kinase
E4F1 E4F transcription factor 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERN1 endoplasmic reticulum to nucleus signaling 1
ERO1L ERO1-like (S. cerevisiae)
F2 coagulation factor II (thrombin)
FAM117A family with sequence similarity 117, member A
FKBP2 FK506 binding protein 2, 13kDa
FOXC1 forkhead box C1
FUZ fuzzy planar cell polarity protein
GMIP GEM interacting protein
GRIP2 glutamate receptor interacting protein 2
GRM4 glutamate receptor, metabotropic 4
GUCA2A guanylate cyclase activator 2A (guanylin)
HIST1H2AJ histone cluster 1, H2aj
HSPA1A heat shock 70kDa protein 1A
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KREMEN2 kringle containing transmembrane protein 2
LEFTY2 left-right determination factor 2
LIAS lipoic acid synthetase
LRRC61 leucine rich repeat containing 61
LZTR1 leucine-zipper-like transcription regulator 1
MAL mal, T-cell differentiation protein
MAP6D1 MAP6 domain containing 1
MEGF6 multiple EGF-like-domains 6
MFSD12 major facilitator superfamily domain containing 12
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MOB3B MOB kinase activator 3B
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEUROD6 neuronal differentiation 6
NR0B2 nuclear receptor subfamily 0, group B, member 2
OXLD1 oxidoreductase-like domain containing 1
PIGR polymeric immunoglobulin receptor
PP14571 uncharacterized LOC100130449
PQLC3 PQ loop repeat containing 3
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
RAD54L RAD54-like (S. cerevisiae)
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFXANK regulatory factor X-associated ankyrin-containing protein
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RRAS related RAS viral (r-ras) oncogene homolog
SAMHD1 SAM domain and HD domain 1
SDS serine dehydratase
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC46A3 solute carrier family 46, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMA4 glucuronidase, beta pseudogene
SNTA1 syntrophin, alpha 1
SPEF1 sperm flagellar 1
STAC SH3 and cysteine rich domain
SURF2 surfeit 2
TBL3 transducin (beta)-like 3
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TMEM127 transmembrane protein 127
TMPRSS5 transmembrane protease, serine 5
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTC4 tetratricopeptide repeat domain 4
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XYLT2 xylosyltransferase II
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF14 zinc finger protein 14
ZNF394 zinc finger protein 394
ZNF408 zinc finger protein 408
ZNF580 zinc finger protein 580
ZNF701 zinc finger protein 701