2-aminobenzenesulfonamide-3400 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the 2-aminobenzenesulfonamide-3400 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AGMAT agmatine ureohydrolase (agmatinase)
AHSP alpha hemoglobin stabilizing protein
ANGPT4 angiopoietin 4
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARC activity-regulated cytoskeleton-associated protein
ARL14 ADP-ribosylation factor-like 14
ATXN7L1 ataxin 7-like 1
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF12 chromosome 10 open reading frame 12
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCR1 chemokine (C-C motif) receptor 1
CD48 CD48 molecule
CDH8 cadherin 8, type 2
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL6A1 collagen, type VI, alpha 1
COMMD4 COMM domain containing 4
CPN2 carboxypeptidase N, polypeptide 2
CRHR2 corticotropin releasing hormone receptor 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CXXC4 CXXC finger protein 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DEFB126 defensin, beta 126
DFNB31 deafness, autosomal recessive 31
DGCR8 DGCR8 microprocessor complex subunit
DHRS7 dehydrogenase/reductase (SDR family) member 7
DOK4 docking protein 4
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELP6 elongator acetyltransferase complex subunit 6
EPHB6 EPH receptor B6
ERC2-IT1 ERC2 intronic transcript 1
ERO1LB ERO1-like beta (S. cerevisiae)
FGR FGR proto-oncogene, Src family tyrosine kinase
FHL1 four and a half LIM domains 1
FRMD4A FERM domain containing 4A
GK glycerol kinase
GPER1 G protein-coupled estrogen receptor 1
GPR3 G protein-coupled receptor 3
GREB1L growth regulation by estrogen in breast cancer-like
HGD homogentisate 1,2-dioxygenase
HOXB6 homeobox B6
HSF2BP heat shock transcription factor 2 binding protein
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IGL immunoglobulin lambda locus
INSL4 insulin-like 4 (placenta)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LCAT lecithin-cholesterol acyltransferase
LEFTY2 left-right determination factor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00574 long intergenic non-protein coding RNA 574
LRRC6 leucine rich repeat containing 6
LY6G6C lymphocyte antigen 6 complex, locus G6C
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP1A microtubule-associated protein 1A
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRPL41 mitochondrial ribosomal protein L41
MYBPC3 myosin binding protein C, cardiac
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOF myoferlin
NF1 neurofibromin 1
NOX1 NADPH oxidase 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PCNXL2 pecanex-like 2 (Drosophila)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POU2F2 POU class 2 homeobox 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG4 pregnancy specific beta-1-glycoprotein 4
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PYY peptide YY
RAB3B RAB3B, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RIMS1 regulating synaptic membrane exocytosis 1
RNF122 ring finger protein 122
RPL10 ribosomal protein L10
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC43A3 solute carrier family 43, member 3
SOCS3 suppressor of cytokine signaling 3
SPAG7 sperm associated antigen 7
SPEF1 sperm flagellar 1
SPTBN1 spectrin, beta, non-erythrocytic 1
TMEM212 transmembrane protein 212
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPMT thiopurine S-methyltransferase
TRBC1 T cell receptor beta constant 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TTC38 tetratricopeptide repeat domain 38
ZC2HC1C zinc finger, C2HC-type containing 1C
ZDHHC14 zinc finger, DHHC-type containing 14
ZMAT4 zinc finger, matrin-type 4
ZNF362 zinc finger protein 362
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFF4 AF4/FMR2 family, member 4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP12 Rho GTPase activating protein 12
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARSB arylsulfatase B
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BHLHE41 basic helix-loop-helix family, member e41
C10ORF95 chromosome 10 open reading frame 95
C11ORF63 chromosome 11 open reading frame 63
CCDC132 coiled-coil domain containing 132
CCDC186 coiled-coil domain containing 186
CCNK cyclin K
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CIDEB cell death-inducing DFFA-like effector b
CLGN calmegin
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRIP1 cysteine-rich protein 1 (intestinal)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DET1 de-etiolated homolog 1 (Arabidopsis)
DSC2 desmocollin 2
DVL1 dishevelled segment polarity protein 1
DYM dymeclin
EDAR ectodysplasin A receptor
EMID1 EMI domain containing 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETNK2 ethanolamine kinase 2
FAM155A family with sequence similarity 155, member A
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GDAP1 ganglioside induced differentiation associated protein 1
GPR143 G protein-coupled receptor 143
GPR157 G protein-coupled receptor 157
HDAC7 histone deacetylase 7
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BC histone cluster 1, H2bc
HOXB2 homeobox B2
IPO8 importin 8
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
LAMC2 laminin, gamma 2
LINC00341 long intergenic non-protein coding RNA 341
LOC157562 uncharacterized LOC157562
LZTS3 leucine zipper, putative tumor suppressor family member 3
MFGE8 milk fat globule-EGF factor 8 protein
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTL5 metallothionein-like 5, testis-specific (tesmin)
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NPFFR1 neuropeptide FF receptor 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PADI1 peptidyl arginine deiminase, type I
PARD6B par-6 family cell polarity regulator beta
PCSK7 proprotein convertase subtilisin/kexin type 7
PHF14 PHD finger protein 14
POLM polymerase (DNA directed), mu
POPDC3 popeye domain containing 3
PPT2 palmitoyl-protein thioesterase 2
RAB30 RAB30, member RAS oncogene family
RCAN3 RCAN family member 3
RNF2 ring finger protein 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC46A3 solute carrier family 46, member 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SPEG SPEG complex locus
SPTBN2 spectrin, beta, non-erythrocytic 2
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TCHH trichohyalin
TCP10 t-complex 10
THRAP3 thyroid hormone receptor associated protein 3
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UPP1 uridine phosphorylase 1
VPS9D1 VPS9 domain containing 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR76 WD repeat domain 76
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZFHX4 zinc finger homeobox 4
ZNF280A zinc finger protein 280A
ZNF304 zinc finger protein 304
ZNF480 zinc finger protein 480
ZNF770 zinc finger protein 770