2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=C049584
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Genes

98 genes/proteins interacting with the chemical 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AHR aryl hydrocarbon receptor
AHRR aryl-hydrocarbon receptor repressor
ALB albumin
APC adenomatous polyposis coli
APRT adenine phosphoribosyltransferase
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BRCA1 breast cancer 1, early onset
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND1 cyclin D1
CCNH cyclin H
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
COMT catechol-O-methyltransferase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DNMT1 DNA (cytosine-5-)-methyltransferase 1
EPS8L3 EPS8-like 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FOS FBJ murine osteosarcoma viral oncogene homolog
GPX2 glutathione peroxidase 2
GSTA1 glutathione S-transferase alpha 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HBB hemoglobin, beta
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST3H3 histone cluster 3, H3
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRAS Harvey rat sarcoma viral oncogene homolog
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL2 interleukin 2
IL6ST interleukin 6 signal transducer
INS insulin
JUN jun proto-oncogene
KDM1A lysine (K)-specific demethylase 1A
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NOS2 nitric oxide synthase 2, inducible
NOX1 NADPH oxidase 1
OAT ornithine aminotransferase
ORM1 orosomucoid 1
PDGFA platelet-derived growth factor alpha polypeptide
PGR progesterone receptor
PHB prohibitin
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
POLH polymerase (DNA directed), eta
POLK polymerase (DNA directed) kappa
POR P450 (cytochrome) oxidoreductase
PRL prolactin
PTEN phosphatase and tensin homolog
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RB1 retinoblastoma 1
RBP1 retinol binding protein 1, cellular
SP1 Sp1 transcription factor
STAT5A signal transducer and activator of transcription 5A
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
TNF tumor necrosis factor
TP53 tumor protein p53
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
XPA xeroderma pigmentosum, complementation group A