16-phenyltetranorprostaglandin E2-7541 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 16-phenyltetranorprostaglandin E2-7541 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEBP1 AE binding protein 1
AK1 adenylate kinase 1
AQP3 aquaporin 3 (Gill blood group)
ARID4B AT rich interactive domain 4B (RBP1-like)
BBS7 Bardet-Biedl syndrome 7
BCAP29 B-cell receptor-associated protein 29
C10ORF12 chromosome 10 open reading frame 12
C2ORF27A chromosome 2 open reading frame 27A
CA5BP1 carbonic anhydrase VB pseudogene 1
CACYBP calcyclin binding protein
CCDC93 coiled-coil domain containing 93
CD22 CD22 molecule
CDH18 cadherin 18, type 2
CDK20 cyclin-dependent kinase 20
COL7A1 collagen, type VII, alpha 1
CREBZF CREB/ATF bZIP transcription factor
CTIF CBP80/20-dependent translation initiation factor
CUL7 cullin 7
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK4 docking protein 4
DTNA dystrobrevin, alpha
DZIP3 DAZ interacting zinc finger protein 3
ELF2 E74-like factor 2 (ets domain transcription factor)
EMID1 EMI domain containing 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERCC5 excision repair cross-complementation group 5
FAM149B1 family with sequence similarity 149, member B1
FLJ11292
FSCN1 fascin actin-bundling protein 1
GIMAP5 GTPase, IMAP family member 5
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR153 G protein-coupled receptor 153
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GSK3A glycogen synthase kinase 3 alpha
HDAC7 histone deacetylase 7
HRASLS2 HRAS-like suppressor 2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL15RA interleukin 15 receptor, alpha
IPO8 importin 8
IQCK IQ motif containing K
ISG20 interferon stimulated exonuclease gene 20kDa
KIAA0930 KIAA0930
KIF5C kinesin family member 5C
KRIT1 KRIT1, ankyrin repeat containing
LMF1 lipase maturation factor 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC730101 uncharacterized LOC730101
LRP2 low density lipoprotein receptor-related protein 2
LRP5L low density lipoprotein receptor-related protein 5-like
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LTBP4 latent transforming growth factor beta binding protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL3 methyltransferase like 3
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MSMB microseminoprotein, beta-
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NNT nicotinamide nucleotide transhydrogenase
NPR3 natriuretic peptide receptor 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PASK PAS domain containing serine/threonine kinase
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKP2 plakophilin 2
PKP3 plakophilin 3
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPT2 palmitoyl-protein thioesterase 2
PTBP3 polypyrimidine tract binding protein 3
PTK6 protein tyrosine kinase 6
RAB3D RAB3D, member RAS oncogene family
RAD54B RAD54 homolog B (S. cerevisiae)
RARA retinoic acid receptor, alpha
RARG retinoic acid receptor, gamma
RBL2 retinoblastoma-like 2
RBM19 RNA binding motif protein 19
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNF2 ring finger protein 2
RPGR retinitis pigmentosa GTPase regulator
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SARM1 sterile alpha and TIR motif containing 1
SH3BP2 SH3-domain binding protein 2
SIX1 SIX homeobox 1
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SRD5A3 steroid 5 alpha-reductase 3
TLK1 tousled-like kinase 1
TUSC2 tumor suppressor candidate 2
UBB ubiquitin B
UBQLN4 ubiquilin 4
VPRBP Vpr (HIV-1) binding protein
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF205 zinc finger protein 205

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADCY6 adenylate cyclase 6
ALOX15 arachidonate 15-lipoxygenase
ALPK1 alpha-kinase 1
ASB9 ankyrin repeat and SOCS box containing 9
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C5AR2 complement component 5a receptor 2
CALML5 calmodulin-like 5
CES3 carboxylesterase 3
CHML choroideremia-like (Rab escort protein 2)
CHRM3 cholinergic receptor, muscarinic 3
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIDEC cell death-inducing DFFA-like effector c
CNTD2 cyclin N-terminal domain containing 2
DNAAF2 dynein, axonemal, assembly factor 2
EFCAB2 EF-hand calcium binding domain 2
ERCC2 excision repair cross-complementation group 2
ETV7 ets variant 7
F8 coagulation factor VIII, procoagulant component
FAM169A family with sequence similarity 169, member A
FAM184A family with sequence similarity 184, member A
FAM212B family with sequence similarity 212, member B
FAM86C1 family with sequence similarity 86, member C1
FKRP fukutin related protein
FLJ11710 uncharacterized protein FLJ11710
FOXN2 forkhead box N2
GID4 GID complex subunit 4
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTA4 glutathione S-transferase alpha 4
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSPA1L heat shock 70kDa protein 1-like
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
INPP5J inositol polyphosphate-5-phosphatase J
INSL4 insulin-like 4 (placenta)
IQCG IQ motif containing G
ITPKB inositol-trisphosphate 3-kinase B
JADE1 jade family PHD finger 1
KDM8 lysine (K)-specific demethylase 8
KIAA0894 KIAA0894 protein
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
KLK5 kallikrein-related peptidase 5
LINC00339 long intergenic non-protein coding RNA 339
LNPEP leucyl/cystinyl aminopeptidase
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LZTFL1 leucine zipper transcription factor-like 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFGE8 milk fat globule-EGF factor 8 protein
MITF microphthalmia-associated transcription factor
MST1R macrophage stimulating 1 receptor
MT1HL1 metallothionein 1H-like 1
MTG1 mitochondrial ribosome-associated GTPase 1
MX1 MX dynamin-like GTPase 1
NABP1 nucleic acid binding protein 1
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NHEJ1 nonhomologous end-joining factor 1
NME5 NME/NM23 family member 5
PAX9 paired box 9
PLCD1 phospholipase C, delta 1
PLXNB3 plexin B3
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PORCN porcupine homolog (Drosophila)
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QSER1 glutamine and serine rich 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF25 ring finger protein 25
SCARA3 scavenger receptor class A, member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SOAT2 sterol O-acyltransferase 2
STIM1 stromal interaction molecule 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TGFBR3 transforming growth factor, beta receptor III
TICAM1 toll-like receptor adaptor molecule 1
TMEM121 transmembrane protein 121
TMEM45A transmembrane protein 45A
TMEM8B transmembrane protein 8B
TRIM36 tripartite motif containing 36
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC30A tetratricopeptide repeat domain 30A
WDR25 WD repeat domain 25
ZBED8 zinc finger, BED-type containing 8
ZFHX2 zinc finger homeobox 2
ZMAT5 zinc finger, matrin-type 5
ZNF358 zinc finger protein 358
ZNF646 zinc finger protein 646