16-phenyltetranorprostaglandin E2-7505 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the 16-phenyltetranorprostaglandin E2-7505 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD5 abhydrolase domain containing 5
ACBD4 acyl-CoA binding domain containing 4
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD12 ankyrin repeat domain 12
APC adenomatous polyposis coli
ARC activity-regulated cytoskeleton-associated protein
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BCAM basal cell adhesion molecule (Lutheran blood group)
BLZF1 basic leucine zipper nuclear factor 1
C5 complement component 5
CARTPT CART prepropeptide
CD82 CD82 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDYL chromodomain protein, Y-like
CHKB choline kinase beta
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CSTA cystatin A (stefin A)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DST dystonin
DTNA dystrobrevin, alpha
EHD2 EH-domain containing 2
EIF1 eukaryotic translation initiation factor 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAXDC2 fatty acid hydroxylase domain containing 2
FGL1 fibrinogen-like 1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GAS7 growth arrest-specific 7
GINS3 GINS complex subunit 3 (Psf3 homolog)
GLRX3 glutaredoxin 3
GLS glutaminase
GLS2 glutaminase 2 (liver, mitochondrial)
GPER1 G protein-coupled estrogen receptor 1
GRB10 growth factor receptor-bound protein 10
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLA-F major histocompatibility complex, class I, F
HPN hepsin
INO80D INO80 complex subunit D
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LINC00115 long intergenic non-protein coding RNA 115
LINC00597 long intergenic non-protein coding RNA 597
LOC730101 uncharacterized LOC730101
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LTBP4 latent transforming growth factor beta binding protein 4
MAPK14 mitogen-activated protein kinase 14
MED12 mediator complex subunit 12
MID2 midline 2
MRPL44 mitochondrial ribosomal protein L44
MTMR2 myotubularin related protein 2
MTSS1 metastasis suppressor 1
NUP62CL nucleoporin 62kDa C-terminal like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCNXL2 pecanex-like 2 (Drosophila)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PEX7 peroxisomal biogenesis factor 7
PODNL1 podocan-like 1
PTTG3P pituitary tumor-transforming 3, pseudogene
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RHBDD3 rhomboid domain containing 3
RNF19B ring finger protein 19B
RPL35A ribosomal protein L35a
RPS28 ribosomal protein S28
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETD4 SET domain containing 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMAD4 SMAD family member 4
SMG6 SMG6 nonsense mediated mRNA decay factor
SMIM14 small integral membrane protein 14
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOCS5 suppressor of cytokine signaling 5
SOD2 superoxide dismutase 2, mitochondrial
TAOK2 TAO kinase 2
TBC1D22A TBC1 domain family, member 22A
TFG TRK-fused gene
TMEM231 transmembrane protein 231
TMEM63A transmembrane protein 63A
TRAIP TRAF interacting protein
TRIM14 tripartite motif containing 14
USB1 U6 snRNA biogenesis 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VIPR2 vasoactive intestinal peptide receptor 2
WAS Wiskott-Aldrich syndrome
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF174 zinc finger protein 174
ZNF205 zinc finger protein 205
ZNF37BP zinc finger protein 37B, pseudogene
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM18 ADAM metallopeptidase domain 18
ADTRP androgen-dependent TFPI-regulating protein
ANP32A-IT1 ANP32A intronic transcript 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AXIN1 axin 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BEX4 brain expressed, X-linked 4
BIRC7 baculoviral IAP repeat containing 7
BST1 bone marrow stromal cell antigen 1
CARF calcium responsive transcription factor
CDH10 cadherin 10, type 2 (T2-cadherin)
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CHRM3 cholinergic receptor, muscarinic 3
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN2 chloride channel, voltage-sensitive 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRY2 cryptochrome circadian clock 2
CRYGD crystallin, gamma D
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DAGLA diacylglycerol lipase, alpha
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOC2A double C2-like domains, alpha
EFNA3 ephrin-A3
EML4 echinoderm microtubule associated protein like 4
ETV6 ets variant 6
FADS2 fatty acid desaturase 2
FBXO2 F-box protein 2
FLCN folliculin
FLJ11710 uncharacterized protein FLJ11710
GAMT guanidinoacetate N-methyltransferase
GAN gigaxonin
GEMIN8 gem (nuclear organelle) associated protein 8
GPR87 G protein-coupled receptor 87
HDAC5 histone deacetylase 5
HIST1H2BJ histone cluster 1, H2bj
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
IQSEC2 IQ motif and Sec7 domain 2
IRF2 interferon regulatory factor 2
IRF6 interferon regulatory factor 6
ITPKA inositol-trisphosphate 3-kinase A
JAM3 junctional adhesion molecule 3
KANK3 KN motif and ankyrin repeat domains 3
KIZ kizuna centrosomal protein
KLF3 Kruppel-like factor 3 (basic)
KRT75 keratin 75, type II
LENEP lens epithelial protein
LPAR3 lysophosphatidic acid receptor 3
LZTFL1 leucine zipper transcription factor-like 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MXRA8 matrix-remodelling associated 8
MYO1F myosin IF
NPHP1 nephronophthisis 1 (juvenile)
NRSN2 neurensin 2
NRTN neurturin
NUPL2 nucleoporin like 2
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OVOL1 ovo-like zinc finger 1
PCDHGA9 protocadherin gamma subfamily A, 9
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PYHIN1 pyrin and HIN domain family, member 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RUSC2 RUN and SH3 domain containing 2
SAMHD1 SAM domain and HD domain 1
SCARA3 scavenger receptor class A, member 3
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC46A3 solute carrier family 46, member 3
SLN sarcolipin
SPEG SPEG complex locus
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TEP1 telomerase-associated protein 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMC7 transmembrane channel-like 7
TMEM57 transmembrane protein 57
TPST1 tyrosylprotein sulfotransferase 1
TUBA4B tubulin, alpha 4b
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WFDC2 WAP four-disulfide core domain 2
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZCCHC24 zinc finger, CCHC domain containing 24
ZIC4 Zic family member 4
ZNF10 zinc finger protein 10
ZNF155 zinc finger protein 155
ZNF471 zinc finger protein 471
ZNF586 zinc finger protein 586