15(S)-15-methylprostaglandin E2-7526 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 15(S)-15-methylprostaglandin E2-7526 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKAP12 A kinase (PRKA) anchor protein 12
ANTXR1 anthrax toxin receptor 1
AQP3 aquaporin 3 (Gill blood group)
ASB7 ankyrin repeat and SOCS box containing 7
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BCL2L1 BCL2-like 1
BRCA2 breast cancer 2, early onset
C19ORF40 chromosome 19 open reading frame 40
C1ORF116 chromosome 1 open reading frame 116
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC37L1 cell division cycle 37-like 1
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COPE coatomer protein complex, subunit epsilon
CPT1A carnitine palmitoyltransferase 1A (liver)
CTAGE5 CTAGE family, member 5
CTH cystathionine gamma-lyase
CXCL3 chemokine (C-X-C motif) ligand 3
CYB561 cytochrome b561
DGCR2 DiGeorge syndrome critical region gene 2
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DMBT1 deleted in malignant brain tumors 1
ECE1 endothelin converting enzyme 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EVI5 ecotropic viral integration site 5
FAM214B family with sequence similarity 214, member B
FBXO38 F-box protein 38
FGFR1OP FGFR1 oncogene partner
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GALT galactose-1-phosphate uridylyltransferase
GPALPP1 GPALPP motifs containing 1
HBEGF heparin-binding EGF-like growth factor
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IFITM1 interferon induced transmembrane protein 1
IL11 interleukin 11
IL6 interleukin 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
KDM7A lysine (K)-specific demethylase 7A
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LOC100127972 uncharacterized LOC100127972
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP7 microtubule-associated protein 7
MAX MYC associated factor X
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MRPS12 mitochondrial ribosomal protein S12
MTAP methylthioadenosine phosphorylase
NCOR2 nuclear receptor corepressor 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFYA nuclear transcription factor Y, alpha
NID1 nidogen 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OTUD4 OTU deubiquitinase 4
PCDHGB5 protocadherin gamma subfamily B, 5
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGK1 phosphoglycerate kinase 1
PLXND1 plexin D1
PPT2 palmitoyl-protein thioesterase 2
PRUNE prune exopolyphosphatase
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RARG retinoic acid receptor, gamma
RGS4 regulator of G-protein signaling 4
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERHL2 serine hydrolase-like 2
SIRT3 sirtuin 3
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX13 sorting nexin 13
SS18 synovial sarcoma translocation, chromosome 18
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TBCD tubulin folding cofactor D
TDRD3 tudor domain containing 3
TGFB2 transforming growth factor, beta 2
THBS3 thrombospondin 3
TMEM259 transmembrane protein 259
TMOD3 tropomodulin 3 (ubiquitous)
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOB2 transducer of ERBB2, 2
TOX4 TOX high mobility group box family member 4
TRAF4 TNF receptor-associated factor 4
TRIM29 tripartite motif containing 29
VEGFA vascular endothelial growth factor A
WDR1 WD repeat domain 1
XYLT2 xylosyltransferase II
ZDHHC14 zinc finger, DHHC-type containing 14

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACBD4 acyl-CoA binding domain containing 4
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGAP10 Rho GTPase activating protein 10
ARHGAP22 Rho GTPase activating protein 22
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BCL9 B-cell CLL/lymphoma 9
C14ORF79 chromosome 14 open reading frame 79
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA9 carbonic anhydrase IX
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CCNJL cyclin J-like
CD82 CD82 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CTC1 CTS telomere maintenance complex component 1
CTSK cathepsin K
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EGF epidermal growth factor
FCHO1 FCH domain only 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GMIP GEM interacting protein
GPR3 G protein-coupled receptor 3
HDAC7 histone deacetylase 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HS1BP3 HCLS1 binding protein 3
IL12A interleukin 12A
LAMB2 laminin, beta 2 (laminin S)
LGALS4 lectin, galactoside-binding, soluble, 4
LMNB1 lamin B1
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MRAS muscle RAS oncogene homolog
MYL5 myosin, light chain 5, regulatory
MYLK myosin light chain kinase
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NME5 NME/NM23 family member 5
NUP62CL nucleoporin 62kDa C-terminal like
NUPR1 nuclear protein, transcriptional regulator, 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OLFML3 olfactomedin-like 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
ORAI3 ORAI calcium release-activated calcium modulator 3
OTUD3 OTU deubiquitinase 3
PACS1 phosphofurin acidic cluster sorting protein 1
PALM paralemmin
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLXNB3 plexin B3
PPCDC phosphopantothenoylcysteine decarboxylase
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RIPPLY3 ripply transcriptional repressor 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF43 ring finger protein 43
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
SCG5 secretogranin V
SECISBP2 SECIS binding protein 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMO smoothened, frizzled class receptor
SNHG3 small nucleolar RNA host gene 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STK16 serine/threonine kinase 16
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TENM4 teneurin transmembrane protein 4
TEX40 testis expressed 40
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TKFC triokinase/FMN cyclase
TMEM53 transmembrane protein 53
TUBB2B tubulin, beta 2B class IIb
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
USP20 ubiquitin specific peptidase 20
WRN Werner syndrome, RecQ helicase-like
ZFHX2 zinc finger homeobox 2
ZNF107 zinc finger protein 107
ZNF362 zinc finger protein 362
ZNF573 zinc finger protein 573
ZNF74 zinc finger protein 74
ZNF749 zinc finger protein 749
ZNF862 zinc finger protein 862