11-deoxy-16,16-dimethylprostaglandin E2-7533 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the 11-deoxy-16,16-dimethylprostaglandin E2-7533 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALOX15 arachidonate 15-lipoxygenase
ANK1 ankyrin 1, erythrocytic
APOC4 apolipoprotein C-IV
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL15 ADP-ribosylation factor-like 15
ARNT aryl hydrocarbon receptor nuclear translocator
ATF7IP activating transcription factor 7 interacting protein
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATXN2L ataxin 2-like
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BATF basic leucine zipper transcription factor, ATF-like
C17ORF59 chromosome 17 open reading frame 59
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDKL3 cyclin-dependent kinase-like 3
CHML choroideremia-like (Rab escort protein 2)
CLASP2 cytoplasmic linker associated protein 2
CNOT3 CCR4-NOT transcription complex, subunit 3
COL5A2 collagen, type V, alpha 2
CRYGC crystallin, gamma C
CSNK1G1 casein kinase 1, gamma 1
CYHR1 cysteine/histidine-rich 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DIAPH2 diaphanous-related formin 2
DNAH3 dynein, axonemal, heavy chain 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNASE1L2 deoxyribonuclease I-like 2
DPY19L1P1 DPY19L1 pseudogene 1
EDNRA endothelin receptor type A
EPHB4 EPH receptor B4
EPOR erythropoietin receptor
ESR1 estrogen receptor 1
FBXL8 F-box and leucine-rich repeat protein 8
FGD1 FYVE, RhoGEF and PH domain containing 1
FGFR3 fibroblast growth factor receptor 3
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HIST1H2AI histone cluster 1, H2ai
HIST2H2AA3 histone cluster 2, H2aa3
HRK harakiri, BCL2 interacting protein
IL11 interleukin 11
ITGB4 integrin, beta 4
JMJD6 jumonji domain containing 6
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM4C lysine (K)-specific demethylase 4C
KIAA0040 KIAA0040
LAMP1 lysosomal-associated membrane protein 1
LIMK1 LIM domain kinase 1
LOC441601 septin 7 pseudogene
LTBP4 latent transforming growth factor beta binding protein 4
MAGEA10 melanoma antigen family A10
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MATK megakaryocyte-associated tyrosine kinase
MIER2 mesoderm induction early response 1, family member 2
MON2 MON2 homolog (S. cerevisiae)
NF2 neurofibromin 2 (merlin)
NFE2L3 nuclear factor, erythroid 2-like 3
NFYA nuclear transcription factor Y, alpha
NLE1 notchless homolog 1 (Drosophila)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP188 nucleoporin 188kDa
OVOL1 ovo-like zinc finger 1
PADI3 peptidyl arginine deiminase, type III
PAX9 paired box 9
PDE8B phosphodiesterase 8B
PER1 period circadian clock 1
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRLR prolactin receptor
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB27B RAB27B, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RASAL2 RAS protein activator like 2
RBM5 RNA binding motif protein 5
RFTN1 raftlin, lipid raft linker 1
RNF6 ring finger protein (C3H2C3 type) 6
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SP1 Sp1 transcription factor
SYNGR1 synaptogyrin 1
TECPR2 tectonin beta-propeller repeat containing 2
TLE2 transducin-like enhancer of split 2
TMEM259 transmembrane protein 259
TMPRSS2 transmembrane protease, serine 2
TMPRSS3 transmembrane protease, serine 3
TP63 tumor protein p63
TRIM23 tripartite motif containing 23
TRIM3 tripartite motif containing 3
TSC2 tuberous sclerosis 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZDHHC17 zinc finger, DHHC-type containing 17
ZFPL1 zinc finger protein-like 1
ZNF235 zinc finger protein 235
ZNF250 zinc finger protein 250
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACBD4 acyl-CoA binding domain containing 4
BMP15 bone morphogenetic protein 15
BRSK2 BR serine/threonine kinase 2
C2ORF27A chromosome 2 open reading frame 27A
C2ORF54 chromosome 2 open reading frame 54
CCDC186 coiled-coil domain containing 186
CCL19 chemokine (C-C motif) ligand 19
CCNT1 cyclin T1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEL carboxyl ester lipase
CEP295 centrosomal protein 295kDa
CLTCL1 clathrin, heavy chain-like 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
DMTN dematin actin binding protein
DNA2 DNA replication helicase/nuclease 2
FAM135A family with sequence similarity 135, member A
FAM155A family with sequence similarity 155, member A
FAM46C family with sequence similarity 46, member C
FGF8 fibroblast growth factor 8 (androgen-induced)
FILIP1L filamin A interacting protein 1-like
FLJ22184
FLNC filamin C, gamma
FRAS1 Fraser extracellular matrix complex subunit 1
FRK fyn-related Src family tyrosine kinase
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GEMIN7 gem (nuclear organelle) associated protein 7
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR21 G protein-coupled receptor 21
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H3E histone cluster 1, H3e
HMHA1 histocompatibility (minor) HA-1
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
IFNA10 interferon, alpha 10
IFNA17 interferon, alpha 17
IFNA21 interferon, alpha 21
IFT22 intraflagellar transport 22
IL13 interleukin 13
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCTD17 potassium channel tetramerization domain containing 17
KIAA0754 KIAA0754
KREMEN2 kringle containing transmembrane protein 2
KRT15 keratin 15, type I
LIM2 lens intrinsic membrane protein 2, 19kDa
LINC00652 long intergenic non-protein coding RNA 652
LOXL3 lysyl oxidase-like 3
LTBP2 latent transforming growth factor beta binding protein 2
MBNL3 muscleblind-like splicing regulator 3
MEGF6 multiple EGF-like-domains 6
MEGF8 multiple EGF-like-domains 8
MTCP1 mature T-cell proliferation 1
NKX3-2 NK3 homeobox 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NRTN neurturin
NXPH3 neurexophilin 3
ONECUT2 one cut homeobox 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PALM paralemmin
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE9A phosphodiesterase 9A
PDZK1IP1 PDZK1 interacting protein 1
PNPLA2 patatin-like phospholipase domain containing 2
PRKG2 protein kinase, cGMP-dependent, type II
PROL1 proline rich, lacrimal 1
PRPH peripherin
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNF39 ring finger protein 39
RPL3L ribosomal protein L3-like
S100A7 S100 calcium binding protein A7
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SETD1A SET domain containing 1A
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
STAB2 stabilin 2
TCP10 t-complex 10
TICAM1 toll-like receptor adaptor molecule 1
TMEM45A transmembrane protein 45A
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNNI3 troponin I type 3 (cardiac)
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
VIM vimentin
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF10 zinc finger protein 10
ZNF606 zinc finger protein 606
ZNF701 zinc finger protein 701