10-methoxyharmalan-2893 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 10-methoxyharmalan-2893 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AHI1 Abelson helper integration site 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARR3 arrestin 3, retinal (X-arrestin)
ATM ATM serine/threonine kinase
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BST2 bone marrow stromal cell antigen 2
C10ORF12 chromosome 10 open reading frame 12
C11ORF16 chromosome 11 open reading frame 16
C17ORF59 chromosome 17 open reading frame 59
C22ORF46 chromosome 22 open reading frame 46
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CARTPT CART prepropeptide
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CLTA clathrin, light chain A
COL8A1 collagen, type VIII, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CUL3 cullin 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNM3 dynamin 3
DOK4 docking protein 4
EFNB3 ephrin-B3
EPS8L3 EPS8-like 3
FADS2 fatty acid desaturase 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBLN1 fibulin 1
FBXW12 F-box and WD repeat domain containing 12
FGL1 fibrinogen-like 1
FLOT1 flotillin 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXN3 forkhead box N3
GAB1 GRB2-associated binding protein 1
GJA8 gap junction protein, alpha 8, 50kDa
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GP6 glycoprotein VI (platelet)
GPR135 G protein-coupled receptor 135
GRM8 glutamate receptor, metabotropic 8
GSTP1 glutathione S-transferase pi 1
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMGN5 high mobility group nucleosome binding domain 5
IFNA7 interferon, alpha 7
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KLHL24 kelch-like family member 24
LDB3 LIM domain binding 3
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LOC647070 uncharacterized LOC647070
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MTMR1 myotubularin related protein 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MXRA8 matrix-remodelling associated 8
NBEAL2 neurobeachin-like 2
NFASC neurofascin
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRP1 neuropilin 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCNX pecanex homolog (Drosophila)
PDE4C phosphodiesterase 4C, cAMP-specific
PHF20 PHD finger protein 20
PHF20L1 PHD finger protein 20-like 1
PKNOX1 PBX/knotted 1 homeobox 1
PLAC4 placenta-specific 4
PLLP plasmolipin
POU4F1 POU class 4 homeobox 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PQLC3 PQ loop repeat containing 3
PRDM16 PR domain containing 16
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCE protein kinase C, epsilon
RANBP3 RAN binding protein 3
RHOBTB2 Rho-related BTB domain containing 2
RND1 Rho family GTPase 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SGSH N-sulfoglucosamine sulfohydrolase
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TACSTD2 tumor-associated calcium signal transducer 2
THBD thrombomodulin
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMPRSS15 transmembrane protease, serine 15
TOR4A torsin family 4, member A
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UNC13A unc-13 homolog A (C. elegans)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VCL vinculin
VNN2 vanin 2
WNT16 wingless-type MMTV integration site family, member 16
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF484 zinc finger protein 484
ZNF652 zinc finger protein 652
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAM15 ADAM metallopeptidase domain 15
ANKRD36 ankyrin repeat domain 36
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
CAPN15 calpain 15
CCDC109B coiled-coil domain containing 109B
CCNK cyclin K
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDR2L cerebellar degeneration-related protein 2-like
CEP112 centrosomal protein 112kDa
CIR1 corepressor interacting with RBPJ, 1
CISH cytokine inducible SH2-containing protein
CLCF1 cardiotrophin-like cytokine factor 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CXXC4 CXXC finger protein 4
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDAR ectodysplasin A receptor
EFNA3 ephrin-A3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM184A family with sequence similarity 184, member A
FAM76A family with sequence similarity 76, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GPR176 G protein-coupled receptor 176
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1C GRAM domain containing 1C
GRWD1 glutamate-rich WD repeat containing 1
HDAC11 histone deacetylase 11
HIST1H4F histone cluster 1, H4f
HIST2H2AA3 histone cluster 2, H2aa3
HOXC4 homeobox C4
HOXC5 homeobox C5
HPS6 Hermansky-Pudlak syndrome 6
IFI35 interferon-induced protein 35
IL17RA interleukin 17 receptor A
JRKL JRK-like
KREMEN2 kringle containing transmembrane protein 2
KRI1 KRI1 homolog (S. cerevisiae)
KRT13 keratin 13, type I
KRT24 keratin 24, type I
LOC390998 ribosomal protein L10 pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP2 low density lipoprotein receptor-related protein 2
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP1S microtubule-associated protein 1S
METTL16 methyltransferase like 16
MGC12488
MMD monocyte to macrophage differentiation-associated
MYL5 myosin, light chain 5, regulatory
NCS1 neuronal calcium sensor 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NRSN2 neurensin 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OGFRL1 opioid growth factor receptor-like 1
OSMR oncostatin M receptor
PDLIM2 PDZ and LIM domain 2 (mystique)
PITX2 paired-like homeodomain 2
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PNPLA6 patatin-like phospholipase domain containing 6
PRICKLE3 prickle homolog 3 (Drosophila)
PRPH peripherin
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVRL3 poliovirus receptor-related 3
RETN resistin
RNF2 ring finger protein 2
ROM1 retinal outer segment membrane protein 1
RPL10L ribosomal protein L10-like
RRAGB Ras-related GTP binding B
SKI SKI proto-oncogene
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNX15 sorting nexin 15
SOX12 SRY (sex determining region Y)-box 12
STX1A syntaxin 1A (brain)
SYBU syntabulin (syntaxin-interacting)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAPPC2 trafficking protein particle complex 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTBK2 tau tubulin kinase 2
TYRP1 tyrosinase-related protein 1
UPP1 uridine phosphorylase 1
XAB2 XPA binding protein 2
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZFHX2 zinc finger homeobox 2
ZNF35 zinc finger protein 35
ZNF665 zinc finger protein 665