1,4-bis(2-(3,5-dichloropyridyloxy))benzene Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=C028474
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Genes

85 genes/proteins interacting with the chemical 1,4-bis(2-(3,5-dichloropyridyloxy))benzene from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AXIN2 axin 2
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CCNE2 cyclin E2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CREB1 cAMP responsive element binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
ELK1 ELK1, member of ETS oncogene family
ERBB2 erb-b2 receptor tyrosine kinase 2
FOXM1 forkhead box M1
FOXO1 forkhead box O1
G6PC glucose-6-phosphatase, catalytic subunit
GAB1 GRB2-associated binding protein 1
GADD45B growth arrest and DNA-damage-inducible, beta
GLUL glutamate-ammonia ligase
GSK3B glycogen synthase kinase 3 beta
HNF4A hepatocyte nuclear factor 4, alpha
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED1 mediator complex subunit 1
MET MET proto-oncogene, receptor tyrosine kinase
MKI67 marker of proliferation Ki-67
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA1 nuclear receptor coactivator 1
NCOA6 nuclear receptor coactivator 6
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNA proliferating cell nuclear antigen
PDPK1 3-phosphoinositide dependent protein kinase 1
PLCG1 phospholipase C, gamma 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RBL1 retinoblastoma-like 1
RXRA retinoid X receptor, alpha
SLC19A1 solute carrier family 19 (folate transporter), member 1
SMAD2 SMAD family member 2
SOD1 superoxide dismutase 1, soluble
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TCF4 transcription factor 4
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
YAP1 Yes-associated protein 1