0317956-0000-4331 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the 0317956-0000-4331 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCK2 aarF domain containing kinase 2
AIM1L absent in melanoma 1-like
AK5 adenylate kinase 5
ASPH aspartate beta-hydroxylase
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATXN7L3B ataxin 7-like 3B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
CA14 carbonic anhydrase XIV
CACYBP calcyclin binding protein
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CERS4 ceramide synthase 4
CHAT choline O-acetyltransferase
CLDN9 claudin 9
CNTD2 cyclin N-terminal domain containing 2
CTRL chymotrypsin-like
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DGCR6L DiGeorge syndrome critical region gene 6-like
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSC2 desmocollin 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELN elastin
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
FBXO31 F-box protein 31
FSCN3 fascin actin-bundling protein 3, testicular
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALR3 galanin receptor 3
GLRA3 glycine receptor, alpha 3
GLS glutaminase
GMPR guanosine monophosphate reductase
GOLGA8A golgin A8 family, member A
HIST1H1E histone cluster 1, H1e
ICA1 islet cell autoantigen 1, 69kDa
ICAM5 intercellular adhesion molecule 5, telencephalin
IER3IP1 immediate early response 3 interacting protein 1
IL6ST interleukin 6 signal transducer
INO80D INO80 complex subunit D
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIF5C kinesin family member 5C
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC729164 hCG1732469
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAP4 microtubule-associated protein 4
MAPK8 mitogen-activated protein kinase 8
MED18 mediator complex subunit 18
MED25 mediator complex subunit 25
MEG3 maternally expressed 3 (non-protein coding)
MRPL20 mitochondrial ribosomal protein L20
MRPL41 mitochondrial ribosomal protein L41
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEURL1 neuralized E3 ubiquitin protein ligase 1
NOX1 NADPH oxidase 1
NPTXR neuronal pentraxin receptor
NT5M 5',3'-nucleotidase, mitochondrial
PAPPA2 pappalysin 2
PDCD2 programmed cell death 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLK3 polo-like kinase 3
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POU5F1B POU class 5 homeobox 1B
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKCE protein kinase C, epsilon
PROX1 prospero homeobox 1
RAB2A RAB2A, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB6B RAB6B, member RAS oncogene family
RAP2A RAP2A, member of RAS oncogene family
RIMS2 regulating synaptic membrane exocytosis 2
RNF122 ring finger protein 122
SAYSD1 SAYSVFN motif domain containing 1
SHOX2 short stature homeobox 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD5 SMAD family member 5
SNTG1 syntrophin, gamma 1
SRRT serrate, RNA effector molecule
SULT4A1 sulfotransferase family 4A, member 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAS2R1 taste receptor, type 2, member 1
THBD thrombomodulin
TIMELESS timeless circadian clock
TM2D1 TM2 domain containing 1
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TSC22D2 TSC22 domain family, member 2
TTLL4 tubulin tyrosine ligase-like family member 4
UBE2B ubiquitin-conjugating enzyme E2B
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
WSB1 WD repeat and SOCS box containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZMYM2 zinc finger, MYM-type 2

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTC1 actin, alpha, cardiac muscle 1
ADGRB2 adhesion G protein-coupled receptor B2
AHDC1 AT hook, DNA binding motif, containing 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATAT1 alpha tubulin acetyltransferase 1
AXIN1 axin 1
BIK BCL2-interacting killer (apoptosis-inducing)
C17ORF53 chromosome 17 open reading frame 53
C1ORF54 chromosome 1 open reading frame 54
CARM1 coactivator-associated arginine methyltransferase 1
CD151 CD151 molecule (Raph blood group)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDT1 chromatin licensing and DNA replication factor 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRDL1 chordin-like 1
CLIP2 CAP-GLY domain containing linker protein 2
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CRYBA2 crystallin, beta A2
CUZD1 CUB and zona pellucida-like domains 1
DEAF1 DEAF1 transcription factor
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
FANCE Fanconi anemia, complementation group E
FURIN furin (paired basic amino acid cleaving enzyme)
GPR21 G protein-coupled receptor 21
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HDAC7 histone deacetylase 7
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HYAL3 hyaluronoglucosaminidase 3
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCTD17 potassium channel tetramerization domain containing 17
KDM5C lysine (K)-specific demethylase 5C
KLC2 kinesin light chain 2
KLK5 kallikrein-related peptidase 5
KRI1 KRI1 homolog (S. cerevisiae)
KRT8P12 keratin 8 pseudogene 12
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMO7 LIM domain 7
LRRC61 leucine rich repeat containing 61
MFGE8 milk fat globule-EGF factor 8 protein
MXRA8 matrix-remodelling associated 8
MYO1D myosin ID
MYO1F myosin IF
NRGN neurogranin (protein kinase C substrate, RC3)
NRTN neurturin
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAQR4 progestin and adipoQ receptor family member IV
PCOLCE procollagen C-endopeptidase enhancer
PDLIM2 PDZ and LIM domain 2 (mystique)
PLD2 phospholipase D2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLXNB3 plexin B3
PMPCA peptidase (mitochondrial processing) alpha
POLM polymerase (DNA directed), mu
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRF1 perforin 1 (pore forming protein)
PRSS53 protease, serine, 53
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB5B RAB5B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHBDD3 rhomboid domain containing 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RUSC2 RUN and SH3 domain containing 2
SCAMP4 secretory carrier membrane protein 4
SERGEF secretion regulating guanine nucleotide exchange factor
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBXAS1 thromboxane A synthase 1 (platelet)
TGFBI transforming growth factor, beta-induced, 68kDa
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLN1 talin 1
TOP3B topoisomerase (DNA) III beta
TRAF2 TNF receptor-associated factor 2
TRIM25 tripartite motif containing 25
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSC22D4 TSC22 domain family, member 4
TUBA4B tubulin, alpha 4b
USP20 ubiquitin specific peptidase 20
WBP2 WW domain binding protein 2
WDR18 WD repeat domain 18
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZC3H12A zinc finger CCCH-type containing 12A
ZFHX3 zinc finger homeobox 3
ZNF215 zinc finger protein 215
ZNF358 zinc finger protein 358
ZNF41 zinc finger protein 41
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZYX zyxin