0316684-0000-7098 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the 0316684-0000-7098 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADK adenosine kinase
AHI1 Abelson helper integration site 1
ANAPC5 anaphase promoting complex subunit 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD12 ankyrin repeat domain 12
ARFRP1 ADP-ribosylation factor related protein 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATG2A autophagy related 2A
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCL2L1 BCL2-like 1
BLZF1 basic leucine zipper nuclear factor 1
BRAP BRCA1 associated protein
BRCA2 breast cancer 2, early onset
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C20ORF27 chromosome 20 open reading frame 27
C5ORF28 chromosome 5 open reading frame 28
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CEP104 centrosomal protein 104kDa
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLIP1 CAP-GLY domain containing linker protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF13 DDB1 and CUL4 associated factor 13
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAH3 dynein, axonemal, heavy chain 3
DST dystonin
ERI3 ERI1 exoribonuclease family member 3
FABP4 fatty acid binding protein 4, adipocyte
FGFR1OP FGFR1 oncogene partner
FNTB farnesyltransferase, CAAX box, beta
FSCN1 fascin actin-bundling protein 1
FZD3 frizzled class receptor 3
GLUL glutamate-ammonia ligase
HAUS6 HAUS augmin-like complex, subunit 6
HDAC4 histone deacetylase 4
HSF2 heat shock transcription factor 2
IL17RC interleukin 17 receptor C
IL33 interleukin 33
ISCA1 iron-sulfur cluster assembly 1
ITGB4 integrin, beta 4
ITM2B integral membrane protein 2B
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCTD12 potassium channel tetramerization domain containing 12
KLC2 kinesin light chain 2
KRT10 keratin 10, type I
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4 microtubule-associated protein 4
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MDC1 mediator of DNA-damage checkpoint 1
MET MET proto-oncogene, receptor tyrosine kinase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEFL neurofilament, light polypeptide
NEK1 NIMA-related kinase 1
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NNMT nicotinamide N-methyltransferase
NR2F2 nuclear receptor subfamily 2, group F, member 2
OCEL1 occludin/ELL domain containing 1
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PEX19 peroxisomal biogenesis factor 19
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLEC plectin
PLSCR1 phospholipid scramblase 1
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POTEKP POTE ankyrin domain family, member K, pseudogene
PTHLH parathyroid hormone-like hormone
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD1 RAD1 checkpoint DNA exonuclease
RANGAP1 Ran GTPase activating protein 1
RECQL5 RecQ protein-like 5
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPS10P5 ribosomal protein S10 pseudogene 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUFY3 RUN and FYVE domain containing 3
SETX senataxin
SF3B1 splicing factor 3b, subunit 1, 155kDa
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A44 solute carrier family 25, member 44
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SPAST spastin
STIP1 stress-induced phosphoprotein 1
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM38B transmembrane protein 38B
TMEM97 transmembrane protein 97
TMPO thymopoietin
TRRAP transformation/transcription domain-associated protein
TTC33 tetratricopeptide repeat domain 33
TULP3 tubby like protein 3
UBE2D1 ubiquitin-conjugating enzyme E2D 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YTHDC2 YTH domain containing 2

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AEN apoptosis enhancing nuclease
ANAPC2 anaphase promoting complex subunit 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AXIN1 axin 1
BAX BCL2-associated X protein
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
C11ORF30 chromosome 11 open reading frame 30
C16ORF59 chromosome 16 open reading frame 59
C19ORF40 chromosome 19 open reading frame 40
C4ORF19 chromosome 4 open reading frame 19
CARD8 caspase recruitment domain family, member 8
CHKB choline kinase beta
COG7 component of oligomeric golgi complex 7
CUTC cutC copper transporter
DCAF4 DDB1 and CUL4 associated factor 4
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DUSP9 dual specificity phosphatase 9
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ERCC6 excision repair cross-complementation group 6
ERO1L ERO1-like (S. cerevisiae)
EYA4 EYA transcriptional coactivator and phosphatase 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM222B family with sequence similarity 222, member B
FBXO46 F-box protein 46
FIG4 FIG4 phosphoinositide 5-phosphatase
H1F0 H1 histone family, member 0
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HPS6 Hermansky-Pudlak syndrome 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INF2 inverted formin, FH2 and WH2 domain containing
KCTD7 potassium channel tetramerization domain containing 7
KIFC1 kinesin family member C1
KLHL26 kelch-like family member 26
KPTN kaptin (actin binding protein)
LIF leukemia inhibitory factor
LMBR1L limb development membrane protein 1-like
LMNB1 lamin B1
LRRC37A3 leucine rich repeat containing 37, member A3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MANBA mannosidase, beta A, lysosomal
MCMBP minichromosome maintenance complex binding protein
MDFI MyoD family inhibitor
MFSD11 major facilitator superfamily domain containing 11
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MITF microphthalmia-associated transcription factor
MOSPD3 motile sperm domain containing 3
MXRA8 matrix-remodelling associated 8
NECAB3 N-terminal EF-hand calcium binding protein 3
NINJ1 ninjurin 1
NPM3 nucleophosmin/nucleoplasmin 3
NR2C2 nuclear receptor subfamily 2, group C, member 2
NTSR1 neurotensin receptor 1 (high affinity)
PDLIM2 PDZ and LIM domain 2 (mystique)
PELP1 proline, glutamate and leucine rich protein 1
PEX26 peroxisomal biogenesis factor 26
PFDN6 prefoldin subunit 6
PLD3 phospholipase D family, member 3
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRR15L proline rich 15-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RFTN1 raftlin, lipid raft linker 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SDC3 syndecan 3
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNIP1 Smad nuclear interacting protein 1
SNORA21 small nucleolar RNA, H/ACA box 21
STARD13 StAR-related lipid transfer (START) domain containing 13
STK16 serine/threonine kinase 16
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM21 tripartite motif containing 21
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSPYL2 TSPY-like 2
TXNL4B thioredoxin-like 4B
VEGFB vascular endothelial growth factor B
VEZT vezatin, adherens junctions transmembrane protein
ZC3H3 zinc finger CCCH-type containing 3
ZFYVE16 zinc finger, FYVE domain containing 16
ZMAT5 zinc finger, matrin-type 5
ZNF136 zinc finger protein 136
ZNF350 zinc finger protein 350
ZNF85 zinc finger protein 85