0316684-0000-7052 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the 0316684-0000-7052 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABHD14A abhydrolase domain containing 14A
ABHD6 abhydrolase domain containing 6
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANP32A-IT1 ANP32A intronic transcript 1
APC adenomatous polyposis coli
APP amyloid beta (A4) precursor protein
ARNT aryl hydrocarbon receptor nuclear translocator
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
C6ORF47 chromosome 6 open reading frame 47
C7ORF43 chromosome 7 open reading frame 43
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC9 coiled-coil domain containing 9
CEP164 centrosomal protein 164kDa
CHKB choline kinase beta
CLEC11A C-type lectin domain family 11, member A
CLIP4 CAP-GLY domain containing linker protein family, member 4
COL1A1 collagen, type I, alpha 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DFNB31 deafness, autosomal recessive 31
DNAAF1 dynein, axonemal, assembly factor 1
DOK4 docking protein 4
F9 coagulation factor IX
FBXO42 F-box protein 42
GGT1 gamma-glutamyltransferase 1
GMIP GEM interacting protein
GPER1 G protein-coupled estrogen receptor 1
GSTA4 glutathione S-transferase alpha 4
GYG2 glycogenin 2
HAP1 huntingtin-associated protein 1
HIC2 hypermethylated in cancer 2
HPX hemopexin
HRASLS2 HRAS-like suppressor 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IQCC IQ motif containing C
IQCG IQ motif containing G
ITPK1 inositol-tetrakisphosphate 1-kinase
KAT8 K(lysine) acetyltransferase 8
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KDM4B lysine (K)-specific demethylase 4B
KHSRP KH-type splicing regulatory protein
KLHL25 kelch-like family member 25
KMT2A lysine (K)-specific methyltransferase 2A
LAMP1 lysosomal-associated membrane protein 1
LMBR1L limb development membrane protein 1-like
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP4 microtubule-associated protein 4
MAPK11 mitogen-activated protein kinase 11
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFSD11 major facilitator superfamily domain containing 11
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MKL1 megakaryoblastic leukemia (translocation) 1
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MST1L macrophage stimulating 1-like
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD4 MAX dimerization protein 4
NPM3 nucleophosmin/nucleoplasmin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NYNRIN NYN domain and retroviral integrase containing
ORC5 origin recognition complex, subunit 5
PAPOLG poly(A) polymerase gamma
PEX26 peroxisomal biogenesis factor 26
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLXNB1 plexin B1
PODXL2 podocalyxin-like 2
PPT2 palmitoyl-protein thioesterase 2
RANBP1 RAN binding protein 1
RARA retinoic acid receptor, alpha
RPGR retinitis pigmentosa GTPase regulator
RPS3A ribosomal protein S3A
RREB1 ras responsive element binding protein 1
SAFB scaffold attachment factor B
SATB2 SATB homeobox 2
SBF1 SET binding factor 1
SCARB2 scavenger receptor class B, member 2
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERHL2 serine hydrolase-like 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHARPIN SHANK-associated RH domain interactor
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPINK5 serine peptidase inhibitor, Kazal type 5
SUGP1 SURP and G patch domain containing 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TULP3 tubby like protein 3
WDR62 WD repeat domain 62
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WSCD1 WSC domain containing 1
ZNF573 zinc finger protein 573
ZNF8 zinc finger protein 8
ZNF804A zinc finger protein 804A
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAM15 ADAM metallopeptidase domain 15
ADAP2 ArfGAP with dual PH domains 2
ADGRE5 adhesion G protein-coupled receptor E5
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARRB1 arrestin, beta 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C14ORF93 chromosome 14 open reading frame 93
C19ORF73 chromosome 19 open reading frame 73
C1ORF56 chromosome 1 open reading frame 56
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CARTPT CART prepropeptide
CCDC6 coiled-coil domain containing 6
CCDC68 coiled-coil domain containing 68
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CLCF1 cardiotrophin-like cytokine factor 1
CORO1A coronin, actin binding protein, 1A
CPA4 carboxypeptidase A4
CTNNBIP1 catenin, beta interacting protein 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DUSP4 dual specificity phosphatase 4
EGFL7 EGF-like-domain, multiple 7
EGR3 early growth response 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHA2 EPH receptor A2
FNTB farnesyltransferase, CAAX box, beta
GAR1 GAR1 ribonucleoprotein
GDAP1 ganglioside induced differentiation associated protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2I general transcription factor IIi
IER5 immediate early response 5
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LIG4 ligase IV, DNA, ATP-dependent
LMAN1 lectin, mannose-binding, 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAPK12 mitogen-activated protein kinase 12
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED4 mediator complex subunit 4
MEIS2 Meis homeobox 2
MPDU1 mannose-P-dolichol utilization defect 1
MRPL44 mitochondrial ribosomal protein L44
MT1HL1 metallothionein 1H-like 1
MTERF4 mitochondrial transcription termination factor 4
NDRG4 NDRG family member 4
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NFE2L3 nuclear factor, erythroid 2-like 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OSMR oncostatin M receptor
PCDHA9 protocadherin alpha 9
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLD2 phospholipase D2
PLK2 polo-like kinase 2
POLL polymerase (DNA directed), lambda
PRICKLE3 prickle homolog 3 (Drosophila)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSENEN presenilin enhancer gamma secretase subunit
RAB23 RAB23, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RIBC2 RIB43A domain with coiled-coils 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
ROM1 retinal outer segment membrane protein 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIDT1 SID1 transmembrane family, member 1
SIX1 SIX homeobox 1
SLC25A40 solute carrier family 25, member 40
SOWAHC sosondowah ankyrin repeat domain family member C
SPIN1 spindlin 1
SPRY2 sprouty homolog 2 (Drosophila)
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
SYTL2 synaptotagmin-like 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBCCD1 TBCC domain containing 1
TCP10 t-complex 10
TMC7 transmembrane channel-like 7
TMEM38B transmembrane protein 38B
TMOD3 tropomodulin 3 (ubiquitous)
TMPRSS6 transmembrane protease, serine 6
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TTC26 tetratricopeptide repeat domain 26
VEGFB vascular endothelial growth factor B
YPEL1 yippee-like 1 (Drosophila)
ZNF250 zinc finger protein 250
ZNF253 zinc finger protein 253
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF552 zinc finger protein 552
ZNF574 zinc finger protein 574