0225151-0000-6426 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the 0225151-0000-6426 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ADAM12 ADAM metallopeptidase domain 12
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATAD5 ATPase family, AAA domain containing 5
ATXN2L ataxin 2-like
ATXN7L1 ataxin 7-like 1
ATXN7L3B ataxin 7-like 3B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP1 bone morphogenetic protein 1
C19ORF40 chromosome 19 open reading frame 40
CA12 carbonic anhydrase XII
CCNJ cyclin J
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIB2 calcium and integrin binding family member 2
COL6A1 collagen, type VI, alpha 1
CROCC ciliary rootlet coiled-coil, rootletin
CSF1 colony stimulating factor 1 (macrophage)
CSNK1E casein kinase 1, epsilon
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DEDD death effector domain containing
DGCR8 DGCR8 microprocessor complex subunit
DOCK6 dedicator of cytokinesis 6
DSC2 desmocollin 2
EML2 echinoderm microtubule associated protein like 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FSCN1 fascin actin-bundling protein 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GOSR1 golgi SNAP receptor complex member 1
GREB1L growth regulation by estrogen in breast cancer-like
HIPK1 homeodomain interacting protein kinase 1
HIRA histone cell cycle regulator
HIRIP3 HIRA interacting protein 3
HMOX1 heme oxygenase 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HOOK1 hook microtubule-tethering protein 1
HOXA4 homeobox A4
HOXC8 homeobox C8
HS1BP3 HCLS1 binding protein 3
IRAK4 interleukin-1 receptor-associated kinase 4
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCTD20 potassium channel tetramerization domain containing 20
KCTD7 potassium channel tetramerization domain containing 7
KIF22 kinesin family member 22
KLF13 Kruppel-like factor 13
KLF6 Kruppel-like factor 6
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
MAOA monoamine oxidase A
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MPPE1 metallophosphoesterase 1
NADK NAD kinase
NPEPL1 aminopeptidase-like 1
NUMA1 nuclear mitotic apparatus protein 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POLG polymerase (DNA directed), gamma
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POU2F3 POU class 2 homeobox 3
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRKCH protein kinase C, eta
PRKD1 protein kinase D1
PSKH1 protein serine kinase H1
RAB35 RAB35, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RARG retinoic acid receptor, gamma
RBBP9 retinoblastoma binding protein 9
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPS4Y1 ribosomal protein S4, Y-linked 1
RWDD2A RWD domain containing 2A
S100A13 S100 calcium binding protein A13
SARS2 seryl-tRNA synthetase 2, mitochondrial
SFT2D2 SFT2 domain containing 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
ST7 suppression of tumorigenicity 7
STX2 syntaxin 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
THOC6 THO complex 6
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR2 toll-like receptor 2
TMEM63A transmembrane protein 63A
TRIP11 thyroid hormone receptor interactor 11
TUBA3C tubulin, alpha 3c
UBAP2L ubiquitin associated protein 2-like
UBE2H ubiquitin-conjugating enzyme E2H
USP34 ubiquitin specific peptidase 34
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VCAN versican
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZBTB20 zinc finger and BTB domain containing 20
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF10 zinc finger protein 10
ZNF224 zinc finger protein 224
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
ANOS1 anosmin 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BAHCC1 BAH domain and coiled-coil containing 1
BAK1 BCL2-antagonist/killer 1
BCAS3 breast carcinoma amplified sequence 3
BCL9 B-cell CLL/lymphoma 9
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BICC1 BicC family RNA binding protein 1
C17ORF53 chromosome 17 open reading frame 53
C17ORF70 chromosome 17 open reading frame 70
C1ORF112 chromosome 1 open reading frame 112
C1RL complement component 1, r subcomponent-like
C22ORF46 chromosome 22 open reading frame 46
C6ORF47 chromosome 6 open reading frame 47
CAPN15 calpain 15
CASP8AP2 caspase 8 associated protein 2
CCDC9 coiled-coil domain containing 9
CDK9 cyclin-dependent kinase 9
CDKL3 cyclin-dependent kinase-like 3
CFAP44 cilia and flagella associated protein 44
CIDEB cell death-inducing DFFA-like effector b
CNTNAP3B contactin associated protein-like 3B
COL17A1 collagen, type XVII, alpha 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DPF3 D4, zinc and double PHD fingers, family 3
ELSPBP1 epididymal sperm binding protein 1
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
F8 coagulation factor VIII, procoagulant component
FAM184A family with sequence similarity 184, member A
FAM222B family with sequence similarity 222, member B
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FKBP10 FK506 binding protein 10, 65 kDa
GBX2 gastrulation brain homeobox 2
GPATCH1 G patch domain containing 1
GPATCH2 G patch domain containing 2
GPR15 G protein-coupled receptor 15
HYI hydroxypyruvate isomerase (putative)
KIAA0895 KIAA0895
KIFC3 kinesin family member C3
LYPD1 LY6/PLAUR domain containing 1
MAGEA6 melanoma antigen family A6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED9 mediator complex subunit 9
MLXIPL MLX interacting protein-like
MMP13 matrix metallopeptidase 13
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEK11 NIMA-related kinase 11
NUBP2 nucleotide binding protein 2
NUPL2 nucleoporin like 2
P3H2 prolyl 3-hydroxylase 2
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEG3 paternally expressed 3
PHF14 PHD finger protein 14
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLBD1 phospholipase B domain containing 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POU5F1B POU class 5 homeobox 1B
PQLC2 PQ loop repeat containing 2
SCG5 secretogranin V
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SH3GL2 SH3-domain GRB2-like 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMR3A submaxillary gland androgen regulated protein 3A
ST5 suppression of tumorigenicity 5
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN3 transgelin 3
TEAD3 TEA domain family member 3
THBS3 thrombospondin 3
TIMP4 TIMP metallopeptidase inhibitor 4
TMEM2 transmembrane protein 2
TOR4A torsin family 4, member A
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL7 tubulin tyrosine ligase-like family member 7
UNKL unkempt family zinc finger-like
WNT7A wingless-type MMTV integration site family, member 7A
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF219 zinc finger protein 219
ZNF254 zinc finger protein 254
ZNF415 zinc finger protein 415