0225151-0000-6389 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 0225151-0000-6389 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AGO4 argonaute RISC catalytic component 4
APOL6 apolipoprotein L, 6
ARHGAP33 Rho GTPase activating protein 33
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
AURKA aurora kinase A
BCHE butyrylcholinesterase
BNC1 basonuclin 1
BRCA2 breast cancer 2, early onset
C1QTNF3 C1q and tumor necrosis factor related protein 3
C1RL complement component 1, r subcomponent-like
C20ORF195 chromosome 20 open reading frame 195
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC9 coiled-coil domain containing 9
CD33 CD33 molecule
CDC14A cell division cycle 14A
CDK10 cyclin-dependent kinase 10
CEP162 centrosomal protein 162kDa
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COL9A3 collagen, type IX, alpha 3
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGCR8 DGCR8 microprocessor complex subunit
DNAH17 dynein, axonemal, heavy chain 17
DOPEY2 dopey family member 2
DSC2 desmocollin 2
ELN elastin
ESRRG estrogen-related receptor gamma
FABP6 fatty acid binding protein 6, ileal
FAT4 FAT atypical cadherin 4
FBXO21 F-box protein 21
FOXJ3 forkhead box J3
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GBP1 guanylate binding protein 1, interferon-inducible
GK glycerol kinase
GPC1 glypican 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRM3 glutamate receptor, metabotropic 3
HEG1 heart development protein with EGF-like domains 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSF2 heat shock transcription factor 2
ITGB6 integrin, beta 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT6A keratin 6A, type II
LAMB4 laminin, beta 4
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGOH2P mago-nashi homolog 2, pseudogene
MAP2 microtubule-associated protein 2
MAPK11 mitogen-activated protein kinase 11
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MST1 macrophage stimulating 1
MSX2 msh homeobox 2
MTM1 myotubularin 1
NCALD neurocalcin delta
NDE1 nudE neurodevelopment protein 1
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR2E3 nuclear receptor subfamily 2, group E, member 3
PDE10A phosphodiesterase 10A
PDE4B phosphodiesterase 4B, cAMP-specific
PDE8B phosphodiesterase 8B
PDLIM5 PDZ and LIM domain 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIAS4 protein inhibitor of activated STAT, 4
PICALM phosphatidylinositol binding clathrin assembly protein
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPARD peroxisome proliferator-activated receptor delta
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSG4 pregnancy specific beta-1-glycoprotein 4
PTK6 protein tyrosine kinase 6
RGS12 regulator of G-protein signaling 12
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFRP4 secreted frizzled-related protein 4
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT3 sirtuin 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORBS1 sorbin and SH3 domain containing 1
SPN sialophorin
SPRR1A small proline-rich protein 1A
STX6 syntaxin 6
SUGP1 SURP and G patch domain containing 1
TBL1Y transducin (beta)-like 1, Y-linked
TBXA2R thromboxane A2 receptor
THRAP3 thyroid hormone receptor associated protein 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLK1 tousled-like kinase 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIO trio Rho guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
AADAC arylacetamide deacetylase
AFF4 AF4/FMR2 family, member 4
AHSP alpha hemoglobin stabilizing protein
ALOX15B arachidonate 15-lipoxygenase, type B
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
ASPN asporin
BCAS1 breast carcinoma amplified sequence 1
BEGAIN brain-enriched guanylate kinase-associated
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD247 CD247 molecule
CIDEB cell death-inducing DFFA-like effector b
CRMP1 collapsin response mediator protein 1
CRYGC crystallin, gamma C
CSRNP3 cysteine-serine-rich nuclear protein 3
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDN dendrin
DOK2 docking protein 2, 56kDa
DSC1 desmocollin 1
DUSP2 dual specificity phosphatase 2
ECM1 extracellular matrix protein 1
ETV7 ets variant 7
F13B coagulation factor XIII, B polypeptide
FAM110B family with sequence similarity 110, member B
FES FES proto-oncogene, tyrosine kinase
FHL3 four and a half LIM domains 3
GIF gastric intrinsic factor (vitamin B synthesis)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR182 G protein-coupled receptor 182
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLX H2.0-like homeobox
HOXB3 homeobox B3
HYAL3 hyaluronoglucosaminidase 3
IL22 interleukin 22
IMPG2 interphotoreceptor matrix proteoglycan 2
IQSEC2 IQ motif and Sec7 domain 2
KHDC1L KH homology domain containing 1-like
KIAA1456 KIAA1456
LIME1 Lck interacting transmembrane adaptor 1
LOC100294391 uncharacterized LOC100294391
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LSP1 lymphocyte-specific protein 1
MLXIPL MLX interacting protein-like
MORN1 MORN repeat containing 1
MRPL41 mitochondrial ribosomal protein L41
NDNF neuron-derived neurotrophic factor
NPHP1 nephronophthisis 1 (juvenile)
NPY4R neuropeptide Y receptor Y4
NR2E1 nuclear receptor subfamily 2, group E, member 1
NTN3 netrin 3
NTNG1 netrin G1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR7C1 olfactory receptor, family 7, subfamily C, member 1
PARM1 prostate androgen-regulated mucin-like protein 1
PCDHB1 protocadherin beta 1
PDE5A phosphodiesterase 5A, cGMP-specific
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGAM2 phosphoglycerate mutase 2 (muscle)
PGP phosphoglycolate phosphatase
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G3 phospholipase A2, group III
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PRAMEF10 PRAME family member 10
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRL prolactin
RAB36 RAB36, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40AL RAB40A, member RAS oncogene family-like
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REC8 REC8 meiotic recombination protein
RIC3 RIC3 acetylcholine receptor chaperone
RND1 Rho family GTPase 1
RPL23AP53 ribosomal protein L23a pseudogene 53
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLMO1 slowmo homolog 1 (Drosophila)
SMAD5-AS1 SMAD5 antisense RNA 1
STAT4 signal transducer and activator of transcription 4
STRN striatin, calmodulin binding protein
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D2 TBC1 domain family, member 2
TDRD12 tudor domain containing 12
TIAM2 T-cell lymphoma invasion and metastasis 2
TLR5 toll-like receptor 5
TMEM212 transmembrane protein 212
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TOM1L2 target of myb1-like 2 (chicken)
TSNAXIP1 translin-associated factor X interacting protein 1
UPK3B uroplakin 3B
VNN1 vanin 1
WDR25 WD repeat domain 25
WDR33 WD repeat domain 33
ZNF362 zinc finger protein 362
ZNF385D zinc finger protein 385D
ZNF606 zinc finger protein 606