0225151-0000-6384 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 0225151-0000-6384 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRA2 adhesion G protein-coupled receptor A2
AGTR2 angiotensin II receptor, type 2
AIRE autoimmune regulator
ALPK1 alpha-kinase 1
ANKRD55 ankyrin repeat domain 55
APP amyloid beta (A4) precursor protein
BGN biglycan
BMP10 bone morphogenetic protein 10
C19ORF66 chromosome 19 open reading frame 66
C19ORF73 chromosome 19 open reading frame 73
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5AR1 complement component 5a receptor 1
CA5A carbonic anhydrase VA, mitochondrial
CA6 carbonic anhydrase VI
CAPN2 calpain 2, (m/II) large subunit
CARD10 caspase recruitment domain family, member 10
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC134 coiled-coil domain containing 134
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
CLEC11A C-type lectin domain family 11, member A
CLSTN3 calsyntenin 3
COL3A1 collagen, type III, alpha 1
COL6A2 collagen, type VI, alpha 2
CSN2 casein beta
CSNK1G1 casein kinase 1, gamma 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYHR1 cysteine/histidine-rich 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAPK2 death-associated protein kinase 2
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DPF1 D4, zinc and double PHD fingers family 1
DRD2 dopamine receptor D2
EFNA3 ephrin-A3
EGF epidermal growth factor
ELP6 elongator acetyltransferase complex subunit 6
EPS8L1 EPS8-like 1
ESR1 estrogen receptor 1
FABP6 fatty acid binding protein 6, ileal
FYB FYN binding protein
GAS7 growth arrest-specific 7
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GRB10 growth factor receptor-bound protein 10
GRM7 glutamate receptor, metabotropic 7
HEG1 heart development protein with EGF-like domains 1
HFE hemochromatosis
HIST1H2AI histone cluster 1, H2ai
HLF hepatic leukemia factor
ICOSLG inducible T-cell co-stimulator ligand
IGFBP3 insulin-like growth factor binding protein 3
IGKV1D-13 immunoglobulin kappa variable 1D-13
IGL immunoglobulin lambda locus
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAG1 jagged 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIF5C kinesin family member 5C
KRT6B keratin 6B, type II
LOC51145 uncharacterized LOC51145
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAN1C1 mannosidase, alpha, class 1C, member 1
MDM4 MDM4, p53 regulator
MEGF6 multiple EGF-like-domains 6
MET MET proto-oncogene, receptor tyrosine kinase
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
NOD2 nucleotide-binding oligomerization domain containing 2
ONECUT1 one cut homeobox 1
OR7A5 olfactory receptor, family 7, subfamily A, member 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4A phosphodiesterase 4A, cAMP-specific
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POU3F4 POU class 3 homeobox 4
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTH2R parathyroid hormone 2 receptor
PTMS parathymosin
PTPRO protein tyrosine phosphatase, receptor type, O
RAB6B RAB6B, member RAS oncogene family
RNF6 ring finger protein (C3H2C3 type) 6
RPL7 ribosomal protein L7
RRH retinal pigment epithelium-derived rhodopsin homolog
RUNDC3A RUN domain containing 3A
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SP100 SP100 nuclear antigen
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRCAP Snf2-related CREBBP activator protein
SRRT serrate, RNA effector molecule
SYT5 synaptotagmin V
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
THSD4 thrombospondin, type I, domain containing 4
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMCC2 transmembrane and coiled-coil domain family 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
VCAN versican
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)

decreased expression

Symbol Name
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARC activity-regulated cytoskeleton-associated protein
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BTNL2 butyrophilin-like 2
C10ORF95 chromosome 10 open reading frame 95
C8ORF44 chromosome 8 open reading frame 44
CCL22 chemokine (C-C motif) ligand 22
CCNK cyclin K
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD53 CD53 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH19 cadherin 19, type 2
CEMIP cell migration inducing protein, hyaluronan binding
CEP295 centrosomal protein 295kDa
CFAP44 cilia and flagella associated protein 44
CHRM3 cholinergic receptor, muscarinic 3
CLDN11 claudin 11
CLDN14 claudin 14
CORO7 coronin 7
CPA2 carboxypeptidase A2 (pancreatic)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGKE diacylglycerol kinase, epsilon 64kDa
DKFZP434C153 DKFZP434C153 protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ENO3 enolase 3 (beta, muscle)
ERCC2 excision repair cross-complementation group 2
ETV4 ets variant 4
FAM131B family with sequence similarity 131, member B
FBXO4 F-box protein 4
GCKR glucokinase (hexokinase 4) regulator
GIPR gastric inhibitory polypeptide receptor
GLB1L galactosidase, beta 1-like
GLDC glycine dehydrogenase (decarboxylating)
GPR65 G protein-coupled receptor 65
HIST1H2BJ histone cluster 1, H2bj
HYAL3 hyaluronoglucosaminidase 3
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
LAMP3 lysosomal-associated membrane protein 3
LCT lactase
LECT2 leukocyte cell-derived chemotaxin 2
LHB luteinizing hormone beta polypeptide
LIG4 ligase IV, DNA, ATP-dependent
LINC01587 long intergenic non-protein coding RNA 1587
LY6G6D lymphocyte antigen 6 complex, locus G6D
MFGE8 milk fat globule-EGF factor 8 protein
MMP25 matrix metallopeptidase 25
MORC1 MORC family CW-type zinc finger 1
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAT6 N-acetyltransferase 6 (GCN5-related)
NLK nemo-like kinase
NOL12 nucleolar protein 12
PAX6 paired box 6
PCDHB11 protocadherin beta 11
PGBD5 piggyBac transposable element derived 5
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLSCR4 phospholipid scramblase 4
POLL polymerase (DNA directed), lambda
POU3F2 POU class 3 homeobox 2
PYHIN1 pyrin and HIN domain family, member 1
RELN reelin
RNF122 ring finger protein 122
RPS4Y1 ribosomal protein S4, Y-linked 1
RSG1 REM2 and RAB-like small GTPase 1
SAA4 serum amyloid A4, constitutive
SATB1 SATB homeobox 1
SCARA3 scavenger receptor class A, member 3
SETD1B SET domain containing 1B
SH2D3C SH2 domain containing 3C
SHANK1 SH3 and multiple ankyrin repeat domains 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLPI secretory leukocyte peptidase inhibitor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPTBN2 spectrin, beta, non-erythrocytic 2
STAB2 stabilin 2
SYNPO synaptopodin
SYT13 synaptotagmin XIII
TACR3 tachykinin receptor 3
TLR2 toll-like receptor 2
TMPRSS4 transmembrane protease, serine 4
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TTLL1 tubulin tyrosine ligase-like family member 1
VIM vimentin
YPEL1 yippee-like 1 (Drosophila)
ZIC3 Zic family member 3
ZNF423 zinc finger protein 423
ZNF532 zinc finger protein 532
ZNF613 zinc finger protein 613
ZNF646 zinc finger protein 646
ZSCAN2 zinc finger and SCAN domain containing 2