0198306-0000-7099 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 0198306-0000-7099 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD12 ankyrin repeat domain 12
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASB9 ankyrin repeat and SOCS box containing 9
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP9B ATPase, class II, type 9B
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCR breakpoint cluster region
BICD1 bicaudal D homolog 1 (Drosophila)
C2ORF68 chromosome 2 open reading frame 68
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CERK ceramide kinase
CREM cAMP responsive element modulator
CUL9 cullin 9
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DLX4 distal-less homeobox 4
FAM65A family with sequence similarity 65, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FBXO31 F-box protein 31
GAN gigaxonin
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GOSR2 golgi SNAP receptor complex member 2
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
HINFP histone H4 transcription factor
HSPA2 heat shock 70kDa protein 2
HTATSF1 HIV-1 Tat specific factor 1
INPP5K inositol polyphosphate-5-phosphatase K
KAT2A K(lysine) acetyltransferase 2A
KIAA0141 KIAA0141
LHX1 LIM homeobox 1
LIN7A lin-7 homolog A (C. elegans)
MAP7D3 MAP7 domain containing 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MERTK MER proto-oncogene, tyrosine kinase
MR1 major histocompatibility complex, class I-related
MT1G metallothionein 1G
MYOF myoferlin
NDRG2 NDRG family member 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLK nemo-like kinase
NOTCH2 notch 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OGFR opioid growth factor receptor
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PASK PAS domain containing serine/threonine kinase
PEMT phosphatidylethanolamine N-methyltransferase
PLCH1 phospholipase C, eta 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POLH polymerase (DNA directed), eta
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRKCA protein kinase C, alpha
PRMT7 protein arginine methyltransferase 7
PRODH proline dehydrogenase (oxidase) 1
PRPF6 pre-mRNA processing factor 6
PSPH phosphoserine phosphatase
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PYCRL pyrroline-5-carboxylate reductase-like
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RIN1 Ras and Rab interactor 1
RND2 Rho family GTPase 2
RPL13 ribosomal protein L13
RPS28 ribosomal protein S28
RREB1 ras responsive element binding protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUFY3 RUN and FYVE domain containing 3
SERBP1 SERPINE1 mRNA binding protein 1
SH3BP2 SH3-domain binding protein 2
SIRT3 sirtuin 3
SIRT6 sirtuin 6
SMIM8 small integral membrane protein 8
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SOD2 superoxide dismutase 2, mitochondrial
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SYBU syntabulin (syntaxin-interacting)
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TP53I11 tumor protein p53 inducible protein 11
TRA2A transformer 2 alpha homolog (Drosophila)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRAK2 trafficking protein, kinesin binding 2
TRMT61A tRNA methyltransferase 61A
TTC12 tetratricopeptide repeat domain 12
TUBGCP4 tubulin, gamma complex associated protein 4
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZBTB38 zinc finger and BTB domain containing 38
ZFPL1 zinc finger protein-like 1
ZNF174 zinc finger protein 174
ZNF253 zinc finger protein 253
ZNF292 zinc finger protein 292
ZNF473 zinc finger protein 473
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABHD14A abhydrolase domain containing 14A
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BAK1 BCL2-antagonist/killer 1
BFSP1 beaded filament structural protein 1, filensin
BIK BCL2-interacting killer (apoptosis-inducing)
C19ORF40 chromosome 19 open reading frame 40
C7ORF43 chromosome 7 open reading frame 43
CALHM2 calcium homeostasis modulator 2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK3 cyclin-dependent kinase 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEPTOR DEP domain containing MTOR-interacting protein
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EGR3 early growth response 3
ELMO3 engulfment and cell motility 3
FOSL1 FOS-like antigen 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
HDAC7 histone deacetylase 7
HIST1H2AJ histone cluster 1, H2aj
HOXC8 homeobox C8
IER5 immediate early response 5
IFI35 interferon-induced protein 35
IGFBP6 insulin-like growth factor binding protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL15RA interleukin 15 receptor, alpha
IL4R interleukin 4 receptor
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM7A lysine (K)-specific demethylase 7A
KIAA0020 KIAA0020
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMBR1L limb development membrane protein 1-like
LRRC61 leucine rich repeat containing 61
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MICALL2 MICAL-like 2
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MMD monocyte to macrophage differentiation-associated
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MOSPD3 motile sperm domain containing 3
NAV2 neuron navigator 2
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHA6 protocadherin alpha 6
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PNPLA6 patatin-like phospholipase domain containing 6
POMT2 protein-O-mannosyltransferase 2
PTPRE protein tyrosine phosphatase, receptor type, E
PVRL3 poliovirus receptor-related 3
QSER1 glutamine and serine rich 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RFTN1 raftlin, lipid raft linker 1
RGS17 regulator of G-protein signaling 17
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD8 SET domain containing (lysine methyltransferase) 8
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC41A3 solute carrier family 41, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOWAHC sosondowah ankyrin repeat domain family member C
SOX12 SRY (sex determining region Y)-box 12
SRBD1 S1 RNA binding domain 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STRA6 stimulated by retinoic acid 6
STX1A syntaxin 1A (brain)
SYT17 synaptotagmin XVII
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THOC6 THO complex 6
TICAM1 toll-like receptor adaptor molecule 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM2 transmembrane protein 2
TMEM62 transmembrane protein 62
TMPRSS3 transmembrane protease, serine 3
TPRA1 transmembrane protein, adipocyte asscociated 1
TTLL1 tubulin tyrosine ligase-like family member 1
UBQLN4 ubiquilin 4
VAV1 vav 1 guanine nucleotide exchange factor
WDR76 WD repeat domain 76
WLS wntless Wnt ligand secretion mediator
ZNF573 zinc finger protein 573
ZNF816 zinc finger protein 816