0198306-0000-7069 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the 0198306-0000-7069 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD17B abhydrolase domain containing 17B
AHI1 Abelson helper integration site 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APP amyloid beta (A4) precursor protein
C7ORF43 chromosome 7 open reading frame 43
C9ORF156 chromosome 9 open reading frame 156
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CEP170B centrosomal protein 170B
CIAO1 cytosolic iron-sulfur assembly component 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTC1 CTS telomere maintenance complex component 1
CTNS cystinosin, lysosomal cystine transporter
CTSZ cathepsin Z
CUL5 cullin 5
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DGCR8 DGCR8 microprocessor complex subunit
DMWD dystrophia myotonica, WD repeat containing
ECE1 endothelin converting enzyme 1
ECM1 extracellular matrix protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC1 excision repair cross-complementation group 1
FBLN1 fibulin 1
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FH fumarate hydratase
FLOT1 flotillin 1
HAUS5 HAUS augmin-like complex, subunit 5
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXB5 homeobox B5
ICAM1 intercellular adhesion molecule 1
IL1RAP interleukin 1 receptor accessory protein
ITM2B integral membrane protein 2B
LAMP1 lysosomal-associated membrane protein 1
LIMK1 LIM domain kinase 1
LRRC40 leucine rich repeat containing 40
LYST lysosomal trafficking regulator
MAGOH2P mago-nashi homolog 2, pseudogene
MAOA monoamine oxidase A
MAST2 microtubule associated serine/threonine kinase 2
MED14 mediator complex subunit 14
MLH3 mutL homolog 3
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD3 MAX dimerization protein 3
NPM3 nucleophosmin/nucleoplasmin 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDE8B phosphodiesterase 8B
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PHLDA3 pleckstrin homology-like domain, family A, member 3
PKNOX1 PBX/knotted 1 homeobox 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POMT2 protein-O-mannosyltransferase 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRPH peripherin
RAB35 RAB35, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAI2 retinoic acid induced 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RIMS3 regulating synaptic membrane exocytosis 3
SCAMP5 secretory carrier membrane protein 5
SCAPER S-phase cyclin A-associated protein in the ER
SCML2 sex comb on midleg-like 2 (Drosophila)
SEC63 SEC63 homolog (S. cerevisiae)
SGK2 serum/glucocorticoid regulated kinase 2
SGSM3 small G protein signaling modulator 3
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPN sialophorin
SQSTM1 sequestosome 1
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STYK1 serine/threonine/tyrosine kinase 1
SUN2 Sad1 and UNC84 domain containing 2
TAGLN3 transgelin 3
TBXA2R thromboxane A2 receptor
TMC7 transmembrane channel-like 7
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
TSKU tsukushi, small leucine rich proteoglycan
TTC12 tetratricopeptide repeat domain 12
VASP vasodilator-stimulated phosphoprotein
VCAN versican
ZBTB43 zinc finger and BTB domain containing 43
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF174 zinc finger protein 174
ZNF177 zinc finger protein 177
ZNF287 zinc finger protein 287
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAM15 ADAM metallopeptidase domain 15
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALDOC aldolase C, fructose-bisphosphate
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASB13 ankyrin repeat and SOCS box containing 13
BCAS3 breast carcinoma amplified sequence 3
C16ORF62 chromosome 16 open reading frame 62
C2ORF49 chromosome 2 open reading frame 49
C8ORF44 chromosome 8 open reading frame 44
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD82 CD82 molecule
CDK9 cyclin-dependent kinase 9
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRY2 cryptochrome circadian clock 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DENND3 DENN/MADD domain containing 3
DNAL4 dynein, axonemal, light chain 4
DOCK1 dedicator of cytokinesis 1
DTX2 deltex 2, E3 ubiquitin ligase
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECI1 enoyl-CoA delta isomerase 1
ELP3 elongator acetyltransferase complex subunit 3
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131B family with sequence similarity 131, member B
FAM155A family with sequence similarity 155, member A
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
GAB2 GRB2-associated binding protein 2
GALT galactose-1-phosphate uridylyltransferase
GID4 GID complex subunit 4
GPR3 G protein-coupled receptor 3
GRAMD1C GRAM domain containing 1C
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HMGB3P1 high mobility group box 3 pseudogene 1
HPS6 Hermansky-Pudlak syndrome 6
HS1BP3 HCLS1 binding protein 3
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCTD15 potassium channel tetramerization domain containing 15
KDM3A lysine (K)-specific demethylase 3A
KIAA0895 KIAA0895
KLHL36 kelch-like family member 36
KPNA5 karyopherin alpha 5 (importin alpha 6)
LIG4 ligase IV, DNA, ATP-dependent
LOC257152 uncharacterized LOC257152
LPAR3 lysophosphatidic acid receptor 3
LRRC49 leucine rich repeat containing 49
MAGEA6 melanoma antigen family A6
MAGEH1 melanoma antigen family H1
MATN3 matrilin 3
MCMBP minichromosome maintenance complex binding protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MN1 meningioma (disrupted in balanced translocation) 1
MPDU1 mannose-P-dolichol utilization defect 1
NDE1 nudE neurodevelopment protein 1
NDRG1 N-myc downstream regulated 1
NUPR1 nuclear protein, transcriptional regulator, 1
OSMR oncostatin M receptor
PARD6A par-6 family cell polarity regulator alpha
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PENK proenkephalin
PGM5 phosphoglucomutase 5
PMCH pro-melanin-concentrating hormone
PTK6 protein tyrosine kinase 6
RAB17 RAB17, member RAS oncogene family
RNF113A ring finger protein 113A
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SHROOM2 shroom family member 2
SLC25A40 solute carrier family 25, member 40
SLITRK5 SLIT and NTRK-like family, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPIDR scaffolding protein involved in DNA repair
SREBF2 sterol regulatory element binding transcription factor 2
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
TEP1 telomerase-associated protein 1
TMEM183A transmembrane protein 183A
TMEM57 transmembrane protein 57
TOR4A torsin family 4, member A
TRAIP TRAF interacting protein
TRIM45 tripartite motif containing 45
TSPAN1 tetraspanin 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR13 WD repeat domain 13
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB44 zinc finger and BTB domain containing 44
ZFHX2 zinc finger homeobox 2
ZNF136 zinc finger protein 136
ZNF281 zinc finger protein 281
ZNF286A zinc finger protein 286A
ZNF408 zinc finger protein 408
ZNF426 zinc finger protein 426
ZNF654 zinc finger protein 654