0179445-0000-4289 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the 0179445-0000-4289 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM22 ADAM metallopeptidase domain 22
ADGRE3 adhesion G protein-coupled receptor E3
ADGRF1 adhesion G protein-coupled receptor F1
AFF1 AF4/FMR2 family, member 1
ALDOB aldolase B, fructose-bisphosphate
ALOX15B arachidonate 15-lipoxygenase, type B
AMPD3 adenosine monophosphate deaminase 3
ANTXR1 anthrax toxin receptor 1
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGAP35 Rho GTPase activating protein 35
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ASPH aspartate beta-hydroxylase
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMP2K BMP2 inducible kinase
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C14ORF1 chromosome 14 open reading frame 1
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAPZB capping protein (actin filament) muscle Z-line, beta
CCL22 chemokine (C-C motif) ligand 22
CDRT1 CMT1A duplicated region transcript 1
CLDN17 claudin 17
CLDN8 claudin 8
CLEC3B C-type lectin domain family 3, member B
CLTA clathrin, light chain A
CTRC chymotrypsin C (caldecrin)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DHRS9 dehydrogenase/reductase (SDR family) member 9
DKFZP434C153 DKFZP434C153 protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK4 docking protein 4
EDN1 endothelin 1
ELF1 E74-like factor 1 (ets domain transcription factor)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
FOXN2 forkhead box N2
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GLE1 GLE1 RNA export mediator
GPM6B glycoprotein M6B
GPR107 G protein-coupled receptor 107
GPR17 G protein-coupled receptor 17
GPR52 G protein-coupled receptor 52
GRIK3 glutamate receptor, ionotropic, kainate 3
GRTP1 growth hormone regulated TBC protein 1
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HPS1 Hermansky-Pudlak syndrome 1
JAM2 junctional adhesion molecule 2
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLHL20 kelch-like family member 20
LAMB4 laminin, beta 4
LENEP lens epithelial protein
LINC00115 long intergenic non-protein coding RNA 115
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK10 mitogen-activated protein kinase 10
MED18 mediator complex subunit 18
NCLN nicalin
NCOA2 nuclear receptor coactivator 2
NUP160 nucleoporin 160kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OSBP2 oxysterol binding protein 2
PBRM1 polybromo 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PKP3 plakophilin 3
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RCE1 Ras converting CAAX endopeptidase 1
REEP2 receptor accessory protein 2
RHOBTB3 Rho-related BTB domain containing 3
RIMS2 regulating synaptic membrane exocytosis 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
RRP1B ribosomal RNA processing 1B
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
S1PR1 sphingosine-1-phosphate receptor 1
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SENP6 SUMO1/sentrin specific peptidase 6
SETDB1 SET domain, bifurcated 1
SFTPB surfactant protein B
SHOX2 short stature homeobox 2
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC35F5 solute carrier family 35, member F5
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
THSD4 thrombospondin, type I, domain containing 4
TLE4 transducin-like enhancer of split 4
TMPRSS15 transmembrane protease, serine 15
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TRIO trio Rho guanine nucleotide exchange factor
VAMP5 vesicle-associated membrane protein 5
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF749 zinc finger protein 749
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAT1 adenosine deaminase, tRNA-specific 1
ALPK1 alpha-kinase 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ASF1B anti-silencing function 1B histone chaperone
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C19ORF54 chromosome 19 open reading frame 54
C7ORF49 chromosome 7 open reading frame 49
C9ORF40 chromosome 9 open reading frame 40
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP8AP2 caspase 8 associated protein 2
CBX8 chromobox homolog 8
CDCA3 cell division cycle associated 3
CDT1 chromatin licensing and DNA replication factor 1
CENPB centromere protein B, 80kDa
CENPI centromere protein I
CEP295 centrosomal protein 295kDa
CFAP44 cilia and flagella associated protein 44
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CUL9 cullin 9
DENND4B DENN/MADD domain containing 4B
DFNB31 deafness, autosomal recessive 31
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
FAM86B1 family with sequence similarity 86, member B1
FAM86C1 family with sequence similarity 86, member C1
FANCE Fanconi anemia, complementation group E
FANCF Fanconi anemia, complementation group F
FZD3 frizzled class receptor 3
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTPBP2 GTP binding protein 2
H1F0 H1 histone family, member 0
HDAC4 histone deacetylase 4
HIST1H2AG histone cluster 1, H2ag
HOXB13 homeobox B13
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IL10RB interleukin 10 receptor, beta
JMJD4 jumonji domain containing 4
KDM4D lysine (K)-specific demethylase 4D
KIAA1107 KIAA1107
KLHL36 kelch-like family member 36
KNTC1 kinetochore associated 1
KRCC1 lysine-rich coiled-coil 1
LINC00339 long intergenic non-protein coding RNA 339
LMNB1 lamin B1
LRRC6 leucine rich repeat containing 6
MAGEF1 melanoma antigen family F1
MAVS mitochondrial antiviral signaling protein
MCRS1 microspherule protein 1
MDC1 mediator of DNA-damage checkpoint 1
METTL1 methyltransferase like 1
MKS1 Meckel syndrome, type 1
MORC2 MORC family CW-type zinc finger 2
MTMR11 myotubularin related protein 11
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NTSR1 neurotensin receptor 1 (high affinity)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OSMR oncostatin M receptor
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCOLCE procollagen C-endopeptidase enhancer
PCYOX1L prenylcysteine oxidase 1 like
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLM polymerase (DNA directed), mu
PRAMEF11 PRAME family member 11
PREB prolactin regulatory element binding
PRICKLE3 prickle homolog 3 (Drosophila)
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRR3 proline rich 3
PRSS16 protease, serine, 16 (thymus)
PSRC1 proline/serine-rich coiled-coil 1
PYCRL pyrroline-5-carboxylate reductase-like
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RBM15B RNA binding motif protein 15B
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPP25 ribonuclease P/MRP 25kDa subunit
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
TAGLN3 transgelin 3
TENM4 teneurin transmembrane protein 4
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLN1 talin 1
TMEM185B transmembrane protein 185B
WDR19 WD repeat domain 19
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF324 zinc finger protein 324
ZNF652 zinc finger protein 652
ZNF76 zinc finger protein 76