0175029-0000-7392 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the 0175029-0000-7392 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ADGRL1 adhesion G protein-coupled receptor L1
ADRBK1 adrenergic, beta, receptor kinase 1
AGO4 argonaute RISC catalytic component 4
AKR1C2 aldo-keto reductase family 1, member C2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARL14 ADP-ribosylation factor-like 14
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
ATXN2L ataxin 2-like
BBC3 BCL2 binding component 3
CABIN1 calcineurin binding protein 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC88C coiled-coil domain containing 88C
CCNT2 cyclin T2
CLDN11 claudin 11
CLDN15 claudin 15
CLSTN3 calsyntenin 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNOT4 CCR4-NOT transcription complex, subunit 4
CRY2 cryptochrome circadian clock 2
CSRNP3 cysteine-serine-rich nuclear protein 3
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
DPF1 D4, zinc and double PHD fingers family 1
EED embryonic ectoderm development
EFNA3 ephrin-A3
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EMC3 ER membrane protein complex subunit 3
EML3 echinoderm microtubule associated protein like 3
EN1 engrailed homeobox 1
ETV5 ets variant 5
FAM120C family with sequence similarity 120C
FAM63B family with sequence similarity 63, member B
FBN2 fibrillin 2
FBXL15 F-box and leucine-rich repeat protein 15
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LARP6 La ribonucleoprotein domain family, member 6
LEF1 lymphoid enhancer-binding factor 1
MPZL1 myelin protein zero-like 1
N4BP2L2 NEDD4 binding protein 2-like 2
OAZ2 ornithine decarboxylase antizyme 2
PALMD palmdelphin
PAX9 paired box 9
PCM1 pericentriolar material 1
PHF20 PHD finger protein 20
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PKP4 plakophilin 4
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
PRDM2 PR domain containing 2, with ZNF domain
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRR protein tyrosine phosphatase, receptor type, R
PVT1 Pvt1 oncogene (non-protein coding)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB31 RAB31, member RAS oncogene family
RARG retinoic acid receptor, gamma
RBMS2 RNA binding motif, single stranded interacting protein 2
RHOT2 ras homolog family member T2
RNF122 ring finger protein 122
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS14 ribosomal protein S14
SCARB1 scavenger receptor class B, member 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SND1-IT1 SND1 intronic transcript 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SREBF2 sterol regulatory element binding transcription factor 2
SSX3 synovial sarcoma, X breakpoint 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STRN striatin, calmodulin binding protein
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYNGR1 synaptogyrin 1
TEX261 testis expressed 261
TM2D1 TM2 domain containing 1
TXNRD3 thioredoxin reductase 3
UBE3A ubiquitin protein ligase E3A
WSB1 WD repeat and SOCS box containing 1
YY1 YY1 transcription factor
ZBTB1 zinc finger and BTB domain containing 1
ZBTB20 zinc finger and BTB domain containing 20
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP64 ZFP64 zinc finger protein
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF276 zinc finger protein 276
ZNF277 zinc finger protein 277
ZNF34 zinc finger protein 34

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADAT1 adenosine deaminase, tRNA-specific 1
ADRB2 adrenoceptor beta 2, surface
AEN apoptosis enhancing nuclease
ALPK1 alpha-kinase 1
ANKRD36 ankyrin repeat domain 36
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AURKB aurora kinase B
BBS7 Bardet-Biedl syndrome 7
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCL9 B-cell CLL/lymphoma 9
C11ORF71 chromosome 11 open reading frame 71
C7ORF43 chromosome 7 open reading frame 43
C9ORF114 chromosome 9 open reading frame 114
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBX7 chromobox homolog 7
CCNE2 cyclin E2
CDH7 cadherin 7, type 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CLEC2B C-type lectin domain family 2, member B
CYB5R1 cytochrome b5 reductase 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DDIT3 DNA-damage-inducible transcript 3
DENND4B DENN/MADD domain containing 4B
DEPDC1 DEP domain containing 1
DIXDC1 DIX domain containing 1
DSE dermatan sulfate epimerase
DSN1 DSN1, MIS12 kinetochore complex component
EAF2 ELL associated factor 2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
F3 coagulation factor III (thromboplastin, tissue factor)
FAM188A family with sequence similarity 188, member A
FAM64A family with sequence similarity 64, member A
GSDMD gasdermin D
HPS6 Hermansky-Pudlak syndrome 6
HTRA2 HtrA serine peptidase 2
JMJD4 jumonji domain containing 4
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF20B kinesin family member 20B
LINC00339 long intergenic non-protein coding RNA 339
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MCRS1 microspherule protein 1
METTL1 methyltransferase like 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MOCS3 molybdenum cofactor synthesis 3
MPI mannose phosphate isomerase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUTYH mutY homolog
NARFL nuclear prelamin A recognition factor-like
NOTCH1 notch 1
ODF2 outer dense fiber of sperm tails 2
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAQR3 progestin and adipoQ receptor family member III
PAQR4 progestin and adipoQ receptor family member IV
PARN poly(A)-specific ribonuclease
PHKG2 phosphorylase kinase, gamma 2 (testis)
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRR3 proline rich 3
PSRC1 proline/serine-rich coiled-coil 1
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD51AP1 RAD51 associated protein 1
RBM15B RNA binding motif protein 15B
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RUNX1-IT1 RUNX1 intronic transcript 1
SCARA3 scavenger receptor class A, member 3
SETBP1 SET binding protein 1
SH3GL2 SH3-domain GRB2-like 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A40 solute carrier family 25, member 40
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35A5 solute carrier family 35, member A5
SLC38A10 solute carrier family 38, member 10
SMAD7 SMAD family member 7
SP140L SP140 nuclear body protein-like
SPC25 SPC25, NDC80 kinetochore complex component
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STX17 syntaxin 17
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TEX30 testis expressed 30
THEM6 thioesterase superfamily member 6
TMEM185B transmembrane protein 185B
TMEM2 transmembrane protein 2
TMEM209 transmembrane protein 209
TRAPPC12 trafficking protein particle complex 12
TSEN2 TSEN2 tRNA splicing endonuclease subunit
WDR5B WD repeat domain 5B
WDR76 WD repeat domain 76
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF862 zinc finger protein 862
ZSCAN16 zinc finger and SCAN domain containing 16
ZXDC ZXD family zinc finger C