0175029-0000-6875 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the 0175029-0000-6875 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACTL8 actin-like 8
ACTN1 actinin, alpha 1
ADAM17 ADAM metallopeptidase domain 17
ADGRF5 adhesion G protein-coupled receptor F5
AIM2 absent in melanoma 2
AKAP17A A kinase (PRKA) anchor protein 17A
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
AMH anti-Mullerian hormone
ASIC3 acid sensing (proton gated) ion channel 3
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BTF3P11 basic transcription factor 3 pseudogene 11
CA9 carbonic anhydrase IX
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCNG2 cyclin G2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD47 CD47 molecule
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLEC1B C-type lectin domain family 1, member B
CNN1 calponin 1, basic, smooth muscle
CORT cortistatin
CYBA cytochrome b-245, alpha polypeptide
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCTN1 dynactin 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
FHL1 four and a half LIM domains 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FMO1 flavin containing monooxygenase 1
FSD1 fibronectin type III and SPRY domain containing 1
FUBP1 far upstream element (FUSE) binding protein 1
GAL galanin/GMAP prepropeptide
GGT1 gamma-glutamyltransferase 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GM2A GM2 ganglioside activator
HAPLN1 hyaluronan and proteoglycan link protein 1
HBS1L HBS1-like translational GTPase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA9 homeobox A9
HOXB2 homeobox B2
HSF2 heat shock transcription factor 2
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNA14 interferon, alpha 14
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0368 KIAA0368
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAT2 linker for activation of T cells family, member 2
LMAN1 lectin, mannose-binding, 1
LOC157562 uncharacterized LOC157562
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MB myoglobin
MED14 mediator complex subunit 14
MFAP2 microfibrillar-associated protein 2
MST1 macrophage stimulating 1
MVD mevalonate (diphospho) decarboxylase
NEURL1 neuralized E3 ubiquitin protein ligase 1
NGDN neuroguidin, EIF4E binding protein
NOVA2 neuro-oncological ventral antigen 2
NRF1 nuclear respiratory factor 1
PAQR6 progestin and adipoQ receptor family member VI
PDCD2 programmed cell death 2
PHF20 PHD finger protein 20
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PRSS53 protease, serine, 53
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTMS parathymosin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC23A Sec23 homolog A (S. cerevisiae)
SH3PXD2A SH3 and PX domains 2A
STS steroid sulfatase (microsomal), isozyme S
STX16 syntaxin 16
SYK spleen tyrosine kinase
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAGLN transgelin
TBXA2R thromboxane A2 receptor
TESPA1 thymocyte expressed, positive selection associated 1
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM63A transmembrane protein 63A
TMF1 TATA element modulatory factor 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPM2 tropomyosin 2 (beta)
TSPAN9 tetraspanin 9
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VEGFA vascular endothelial growth factor A
VIPR1 vasoactive intestinal peptide receptor 1
WFDC2 WAP four-disulfide core domain 2
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WNT1 wingless-type MMTV integration site family, member 1
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
AMOTL2 angiomotin like 2
ARL4A ADP-ribosylation factor-like 4A
C11ORF57 chromosome 11 open reading frame 57
C14ORF169 chromosome 14 open reading frame 169
C1ORF106 chromosome 1 open reading frame 106
C2ORF42 chromosome 2 open reading frame 42
C5ORF30 chromosome 5 open reading frame 30
CASP8AP2 caspase 8 associated protein 2
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDCA4 cell division cycle associated 4
CHD1 chromodomain helicase DNA binding protein 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CHSY1 chondroitin sulfate synthase 1
CSRNP2 cysteine-serine-rich nuclear protein 2
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAAF2 dynein, axonemal, assembly factor 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNMBP dynamin binding protein
DOLK dolichol kinase
DPF2 D4, zinc and double PHD fingers family 2
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FADD Fas (TNFRSF6)-associated via death domain
FAM46A family with sequence similarity 46, member A
FBXL14 F-box and leucine-rich repeat protein 14
FBXO34 F-box protein 34
FOXD1 forkhead box D1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FZD2 frizzled class receptor 2
GEMIN4 gem (nuclear organelle) associated protein 4
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
HILPDA hypoxia inducible lipid droplet-associated
HJURP Holliday junction recognition protein
HOXA5 homeobox A5
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INTS5 integrator complex subunit 5
KIN Kin17 DNA and RNA binding protein
LIN37 lin-37 DREAM MuvB core complex component
MAD2L1BP MAD2L1 binding protein
MAP1S microtubule-associated protein 1S
MCM10 minichromosome maintenance complex component 10
MEPCE methylphosphate capping enzyme
MFSD5 major facilitator superfamily domain containing 5
MGA MGA, MAX dimerization protein
MSX1 msh homeobox 1
MTERF3 mitochondrial transcription termination factor 3
NDC80 NDC80 kinetochore complex component
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NXT1 nuclear transport factor 2-like export factor 1
OSBPL11 oxysterol binding protein-like 11
PALB2 partner and localizer of BRCA2
PEX12 peroxisomal biogenesis factor 12
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PNRC2 proline-rich nuclear receptor coactivator 2
PPAN peter pan homolog (Drosophila)
PPP1R10 protein phosphatase 1, regulatory subunit 10
PTCD1 pentatricopeptide repeat domain 1
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RAB20 RAB20, member RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RPP38 ribonuclease P/MRP 38kDa subunit
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCO2 SCO2 cytochrome c oxidase assembly protein
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SMG8 SMG8 nonsense mediated mRNA decay factor
SUOX sulfite oxidase
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBCC tubulin folding cofactor C
TBCCD1 TBCC domain containing 1
TEFM transcription elongation factor, mitochondrial
THAP11 THAP domain containing 11
TMEM115 transmembrane protein 115
TMEM177 transmembrane protein 177
TMEM186 transmembrane protein 186
TMEM51 transmembrane protein 51
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOB1 transducer of ERBB2, 1
TRIM13 tripartite motif containing 13
TRIM24 tripartite motif containing 24
TRIM32 tripartite motif containing 32
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TROAP trophinin associated protein
TWIST1 twist family bHLH transcription factor 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
XBP1 X-box binding protein 1
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBED5 zinc finger, BED-type containing 5
ZCCHC10 zinc finger, CCHC domain containing 10
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF16 zinc finger protein 16
ZNF165 zinc finger protein 165
ZNF184 zinc finger protein 184
ZNF282 zinc finger protein 282
ZNF443 zinc finger protein 443