0173570-0000-4712 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the 0173570-0000-4712 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ADAM11 ADAM metallopeptidase domain 11
ADORA1 adenosine A1 receptor
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMACR alpha-methylacyl-CoA racemase
AMPD3 adenosine monophosphate deaminase 3
AQP3 aquaporin 3 (Gill blood group)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
AVPR1A arginine vasopressin receptor 1A
BAG1 BCL2-associated athanogene
BCO1 beta-carotene oxygenase 1
BDKRB2 bradykinin receptor B2
BGN biglycan
C1ORF54 chromosome 1 open reading frame 54
CA5BP1 carbonic anhydrase VB pseudogene 1
CABP2 calcium binding protein 2
CARD14 caspase recruitment domain family, member 14
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD248 CD248 molecule, endosialin
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEMIP cell migration inducing protein, hyaluronan binding
CFAP45 cilia and flagella associated protein 45
CRMP1 collapsin response mediator protein 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DFNB31 deafness, autosomal recessive 31
DGKI diacylglycerol kinase, iota
DIXDC1 DIX domain containing 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DSG3 desmoglein 3
EGR1 early growth response 1
EIF3F eukaryotic translation initiation factor 3, subunit F
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FGF18 fibroblast growth factor 18
FGFR1 fibroblast growth factor receptor 1
GPR3 G protein-coupled receptor 3
GRK5 G protein-coupled receptor kinase 5
HFE hemochromatosis
HPSE2 heparanase 2 (inactive)
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
ICAM1 intercellular adhesion molecule 1
IDUA iduronidase, alpha-L-
IL18 interleukin 18
IL1RAP interleukin 1 receptor accessory protein
IRS2 insulin receptor substrate 2
JAG1 jagged 1
KIAA1549L KIAA1549-like
KLHL29 kelch-like family member 29
LCMT2 leucine carboxyl methyltransferase 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MORC1 MORC family CW-type zinc finger 1
MYO15A myosin XVA
NAV2 neuron navigator 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NT5M 5',3'-nucleotidase, mitochondrial
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHA6 protocadherin alpha 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLVAP plasmalemma vesicle associated protein
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PQLC2 PQ loop repeat containing 2
PTX3 pentraxin 3, long
RAB11B RAB11B, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RHOBTB2 Rho-related BTB domain containing 2
RIN3 Ras and Rab interactor 3
RPS3A ribosomal protein S3A
RTEL1 regulator of telomere elongation helicase 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERHL2 serine hydrolase-like 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLAMF7 SLAM family member 7
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STMN3 stathmin-like 3
SYNPO synaptopodin
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBL2 transducin (beta)-like 2
TCP11L1 t-complex 11, testis-specific-like 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT3 troponin T type 3 (skeletal, fast)
TNS1 tensin 1
TYRO3 TYRO3 protein tyrosine kinase
VCL vinculin
YTHDC2 YTH domain containing 2
ZC3H7B zinc finger CCCH-type containing 7B
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ANKRD40 ankyrin repeat domain 40
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASAP1-IT1 ASAP1 intronic transcript 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAG4 BCL2-associated athanogene 4
BBC3 BCL2 binding component 3
C22ORF29 chromosome 22 open reading frame 29
CAPG capping protein (actin filament), gelsolin-like
CD79A CD79a molecule, immunoglobulin-associated alpha
CDADC1 cytidine and dCMP deaminase domain containing 1
CLSPN claspin
CORO7 coronin 7
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DTX2 deltex 2, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
ELSPBP1 epididymal sperm binding protein 1
ETAA1 Ewing tumor-associated antigen 1
FRK fyn-related Src family tyrosine kinase
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GMEB1 glucocorticoid modulatory element binding protein 1
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMOX1 heme oxygenase 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INSIG1 insulin induced gene 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM7A lysine (K)-specific demethylase 7A
KIF13A kinesin family member 13A
KIFC1 kinesin family member C1
KLF11 Kruppel-like factor 11
KREMEN2 kringle containing transmembrane protein 2
LHX6 LIM homeobox 6
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LOC257152 uncharacterized LOC257152
LOC730101 uncharacterized LOC730101
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBNL3 muscleblind-like splicing regulator 3
MORC3 MORC family CW-type zinc finger 3
MRPL41 mitochondrial ribosomal protein L41
MSX1 msh homeobox 1
MTERF4 mitochondrial transcription termination factor 4
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEK11 NIMA-related kinase 11
NXN nucleoredoxin
OSR2 odd-skipped related transciption factor 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PITX2 paired-like homeodomain 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMCH pro-melanin-concentrating hormone
POMT2 protein-O-mannosyltransferase 2
PRF1 perforin 1 (pore forming protein)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAD51AP1 RAD51 associated protein 1
RBM4B RNA binding motif protein 4B
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPAIN RPA interacting protein
SCGB2A2 secretoglobin, family 2A, member 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SFT2D2 SFT2 domain containing 2
SKI SKI proto-oncogene
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLIT2 slit homolog 2 (Drosophila)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP140L SP140 nuclear body protein-like
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYCP2 synaptonemal complex protein 2
TET3 tet methylcytosine dioxygenase 3
TIGD6 tigger transposable element derived 6
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM53 transmembrane protein 53
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
UBQLN4 ubiquilin 4
VASH2 vasohibin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR76 WD repeat domain 76
WEE1 WEE1 G2 checkpoint kinase
ZBTB39 zinc finger and BTB domain containing 39
ZBTB44 zinc finger and BTB domain containing 44
ZBTB48 zinc finger and BTB domain containing 48
ZFP69B ZFP69 zinc finger protein B
ZNF136 zinc finger protein 136
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF701 zinc finger protein 701
ZNF74 zinc finger protein 74
ZNF804A zinc finger protein 804A