(+)-isoprenaline-6663 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the (+)-isoprenaline-6663 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACKR3 atypical chemokine receptor 3
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADORA1 adenosine A1 receptor
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AKAP12 A kinase (PRKA) anchor protein 12
AKR1D1 aldo-keto reductase family 1, member D1
ANP32A-IT1 ANP32A intronic transcript 1
AQP3 aquaporin 3 (Gill blood group)
ARPIN actin-related protein 2/3 complex inhibitor
ATP9B ATPase, class II, type 9B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BMP2 bone morphogenetic protein 2
C17ORF59 chromosome 17 open reading frame 59
C6ORF10 chromosome 6 open reading frame 10
C8ORF44 chromosome 8 open reading frame 44
CCNO cyclin O
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC14B cell division cycle 14B
CEMIP cell migration inducing protein, hyaluronan binding
CEP295 centrosomal protein 295kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CORO7 coronin 7
CREM cAMP responsive element modulator
CT62 cancer/testis antigen 62
CTH cystathionine gamma-lyase
CXCL2 chemokine (C-X-C motif) ligand 2
CXCR3 chemokine (C-X-C motif) receptor 3
CYP2A7P1 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMBT1 deleted in malignant brain tumors 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DUSP1 dual specificity phosphatase 1
EED embryonic ectoderm development
EGR1 early growth response 1
EPAS1 endothelial PAS domain protein 1
ETV1 ets variant 1
ETV6 ets variant 6
EZR ezrin
FAM162A family with sequence similarity 162, member A
FGFR1 fibroblast growth factor receptor 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GK glycerol kinase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HAP1 huntingtin-associated protein 1
HBEGF heparin-binding EGF-like growth factor
HEG1 heart development protein with EGF-like domains 1
IL11 interleukin 11
IL1RL1 interleukin 1 receptor-like 1
IL33 interleukin 33
IRF2BP1 interferon regulatory factor 2 binding protein 1
ISG20 interferon stimulated exonuclease gene 20kDa
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLHL22 kelch-like family member 22
KRT17 keratin 17, type I
KRT7 keratin 7, type II
LYPD3 LY6/PLAUR domain containing 3
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP7 microtubule-associated protein 7
MAP7D3 MAP7 domain containing 3
MCF2L MCF.2 cell line derived transforming sequence-like
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTN3 netrin 3
PDE4C phosphodiesterase 4C, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDE8B phosphodiesterase 8B
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PMP22 peripheral myelin protein 22
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
RBM26 RNA binding motif protein 26
RHOH ras homolog family member H
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAMD4A sterile alpha motif domain containing 4A
SARM1 sterile alpha and TIR motif containing 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLA Src-like-adaptor
SMOX spermine oxidase
STC1 stanniocalcin 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TIMELESS timeless circadian clock
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNXB tenascin XB
TRD T cell receptor delta locus
TRIM29 tripartite motif containing 29
VAC14 Vac14 homolog (S. cerevisiae)
WT1 Wilms tumor 1
ZNF10 zinc finger protein 10
ZNF446 zinc finger protein 446
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAM23 ADAM metallopeptidase domain 23
AFAP1 actin filament associated protein 1
APOL6 apolipoprotein L, 6
ARHGAP10 Rho GTPase activating protein 10
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
BCCIP BRCA2 and CDKN1A interacting protein
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BMP15 bone morphogenetic protein 15
C11ORF30 chromosome 11 open reading frame 30
C16ORF59 chromosome 16 open reading frame 59
C3 complement component 3
CCDC85C coiled-coil domain containing 85C
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN4 claudin 4
CNGA1 cyclic nucleotide gated channel alpha 1
CNTNAP3B contactin associated protein-like 3B
COL21A1 collagen, type XXI, alpha 1
CPNE7 copine VII
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DLK2 delta-like 2 homolog (Drosophila)
ELOVL4 ELOVL fatty acid elongase 4
F2R coagulation factor II (thrombin) receptor
FAT4 FAT atypical cadherin 4
FGF23 fibroblast growth factor 23
FRS3 fibroblast growth factor receptor substrate 3
FUZ fuzzy planar cell polarity protein
G0S2 G0/G1 switch 2
GEMIN8 gem (nuclear organelle) associated protein 8
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GPR176 G protein-coupled receptor 176
GRPR gastrin-releasing peptide receptor
HIST1H2BN histone cluster 1, H2bn
HOXC13 homeobox C13
IMPACT impact RWD domain protein
INHBB inhibin, beta B
INO80D INO80 complex subunit D
ISYNA1 inositol-3-phosphate synthase 1
KDM5C lysine (K)-specific demethylase 5C
KIAA1462 KIAA1462
LOC100127972 uncharacterized LOC100127972
LOC257152 uncharacterized LOC257152
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYRM9 LYR motif containing 9
MAMLD1 mastermind-like domain containing 1
MFGE8 milk fat globule-EGF factor 8 protein
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MILR1 mast cell immunoglobulin-like receptor 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NKX3-2 NK3 homeobox 2
NOD1 nucleotide-binding oligomerization domain containing 1
NPY1R neuropeptide Y receptor Y1
NR3C2 nuclear receptor subfamily 3, group C, member 2
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLXNB3 plexin B3
POMT2 protein-O-mannosyltransferase 2
PRR7 proline rich 7 (synaptic)
PRSS53 protease, serine, 53
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPRS protein tyrosine phosphatase, receptor type, S
PTX3 pentraxin 3, long
RAI14 retinoic acid induced 14
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
REPS2 RALBP1 associated Eps domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
ROM1 retinal outer segment membrane protein 1
RUNX1-IT1 RUNX1 intronic transcript 1
SCIN scinderin
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC12A8 solute carrier family 12, member 8
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNAI2 snail family zinc finger 2
SOBP sine oculis binding protein homolog (Drosophila)
SSBP3 single stranded DNA binding protein 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYNGR3 synaptogyrin 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBXAS1 thromboxane A synthase 1 (platelet)
TENM1 teneurin transmembrane protein 1
TMEM132A transmembrane protein 132A
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
VWA1 von Willebrand factor A domain containing 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZNF215 zinc finger protein 215
ZNF253 zinc finger protein 253
ZNF385D zinc finger protein 385D
ZNF408 zinc finger protein 408
ZNF702P zinc finger protein 702, pseudogene