UGT1A Gene

HGNC Family Glycosyltransferases
Name UDP glucuronosyltransferase 1 family, polypeptide A complex locus
Description This RefSeq represents a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. [provided by RefSeq, Jul 2008]
Synonyms GNT1, UGT1A@
NCBI Gene ID 7361
API
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Predicted Functions View UGT1A's ARCHS4 Predicted Functions.
Co-expressed Genes View UGT1A's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View UGT1A's ARCHS4 Predicted Functions.

Functional Associations

UGT1A has 285 functional associations with biological entities spanning 5 categories (organism, chemical, disease, phenotype or trait, functional term, phrase or reference, gene, protein or microRNA) extracted from 11 datasets.

Click the + buttons to view associations for UGT1A from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CTD Gene-Chemical Interactions chemicals interacting with UGT1A gene/protein from the curated CTD Gene-Chemical Interactions dataset.
CTD Gene-Disease Associations diseases associated with UGT1A gene/protein from the curated CTD Gene-Disease Associations dataset.
GAD Gene-Disease Associations diseases associated with UGT1A gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
GAD High Level Gene-Disease Associations diseases associated with UGT1A gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
GeneRIF Biological Term Annotations biological terms co-occuring with UGT1A gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of UGT1A gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of UGT1A gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of UGT1A gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of UGT1A gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
GWAS Catalog SNP-Phenotype Associations phenotypes associated with UGT1A gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.
HuGE Navigator Gene-Phenotype Associations phenotypes associated with UGT1A gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.