GGTLC3 Gene

HGNC Family Gamma-glutamyltransferases (GGT)
Name gamma-glutamyltransferase light chain 3
Description Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC3, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]
Proteins GGTL3_HUMAN
NCBI Gene ID 728226
API
Download Associations
Predicted Functions View GGTLC3's ARCHS4 Predicted Functions.
Co-expressed Genes View GGTLC3's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View GGTLC3's ARCHS4 Predicted Functions.

Functional Associations

GGTLC3 has 82 functional associations with biological entities spanning 2 categories (functional term, phrase or reference, cell line, cell type or tissue) extracted from 7 datasets.

Click the + buttons to view associations for GGTLC3 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing GGTLC3 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing GGTLC3 from the GeneSigDB Published Gene Signatures dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of GGTLC3 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
HPA Cell Line Gene Expression Profiles cell lines with high or low expression of GGTLC3 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset.
HPA Tissue Gene Expression Profiles tissues with high or low expression of GGTLC3 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.
HPA Tissue Sample Gene Expression Profiles tissue samples with high or low expression of GGTLC3 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset.
TISSUES Experimental Tissue Protein Expression Evidence Scores tissues with high expression of GGTLC3 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.