DUX3 Gene

Name double homeobox 3
Description The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX3, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]
Proteins DUX3_HUMAN
NCBI Gene ID 26582
API
Download Associations
Predicted Functions View DUX3's ARCHS4 Predicted Functions.
Co-expressed Genes View DUX3's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View DUX3's ARCHS4 Predicted Functions.

Functional Associations

DUX3 has 253 functional associations with biological entities spanning 4 categories (functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 8 datasets.

Click the + buttons to view associations for DUX3 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Achilles Cell Line Gene Essentiality Profiles cell lines with fitness changed by DUX3 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
GO Cellular Component Annotations cellular components containing DUX3 protein from the curated GO Cellular Component Annotations dataset.
GO Molecular Function Annotations molecular functions performed by DUX3 gene from the curated GO Molecular Function Annotations dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for DUX3 protein from the InterPro Predicted Protein Domain Annotations dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of DUX3 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
LOCATE Curated Protein Localization Annotations cellular components containing DUX3 protein in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain DUX3 protein from the LOCATE Predicted Protein Localization Annotations dataset.
Pathway Commons Protein-Protein Interactions interacting proteins for DUX3 from the Pathway Commons Protein-Protein Interactions dataset.