|Name||double homeobox 3|
|Description||The human genome contains hundreds of repeats of the 3.3-kb family in regions associated with heterochromatin. The DUX gene family, including DUX3, resides within these 3.3-kb repeated elements (Beckers et al., 2001 [PubMed 11245978]). See DUX4 (MIM 606009).[supplied by OMIM, Mar 2008]|
|NCBI Gene ID||26582|
|Expression in Tissues and Cell Lines||
DUX3 has 253 functional associations with biological entities spanning 4 categories (functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 8 datasets.
Click the + buttons to view associations for DUX3 from the datasets below.
If available, associations are ranked by standardized value
|Achilles Cell Line Gene Essentiality Profiles||cell lines with fitness changed by DUX3 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.|
|GO Cellular Component Annotations||cellular components containing DUX3 protein from the curated GO Cellular Component Annotations dataset.|
|GO Molecular Function Annotations||molecular functions performed by DUX3 gene from the curated GO Molecular Function Annotations dataset.|
|InterPro Predicted Protein Domain Annotations||protein domains predicted for DUX3 protein from the InterPro Predicted Protein Domain Annotations dataset.|
|Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles||cell lines with high or low copy number of DUX3 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.|
|LOCATE Curated Protein Localization Annotations||cellular components containing DUX3 protein in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.|
|LOCATE Predicted Protein Localization Annotations||cellular components predicted to contain DUX3 protein from the LOCATE Predicted Protein Localization Annotations dataset.|
|Pathway Commons Protein-Protein Interactions||interacting proteins for DUX3 from the Pathway Commons Protein-Protein Interactions dataset.|