Roadmap Epigenomics Cell and Tissue Gene Expression Profiles Dataset

Description mRNA expression profiles for primary cell types and tissues
Measurement gene expression by RNA-seq
Association gene-cell type or tissue associations by differential expression of gene across cell types and tissues
Category transcriptomics
Resource Roadmap Epigenomics
Citation(s)
Last Updated
Stats
  1. 12824 genes
  2. 57 cell type or tissues
  3. 109318 gene-cell type or tissue associations

Data Access

API
Script

Visualizations

  • Attribute Similarity

  • Dataset

  • Gene Similarity

cell type or tissue Gene Sets

57 sets of genes with high or low expression in each cell type or tissue relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset.

Gene Set Description
4star
A549 Human lung carcinoma established from an explanted lung tumor which was removed from a 58-year-old Caucasian man in 1972; cells were described to induce tumors in athymic mice and to synthesize lecithin.
Adult_Liver
Aorta The great arterial trunk that carries blood from the heart to be distributed by branch arteries through the body.
Brain_Germinal_Matrix
Brain_Hippocampus_Middle
Breast_Myoepithelial_Cells
Breast_vHMEC
CD4_Memory_Primary_Cells
CD4_Naive_Primary_Cells
CD8_Naive_Primary_Cells
Esophagus A muscular tube that in humans is about nine inches (23 centimeters) long and passes from the pharynx down the neck between the trachea and the spinal column and behind the left bronchus where it pierces the diaphragm slightly to the left of the middle line and joins the cardiac end of the stomach.
Fetal_Brain_Female
Fetal_Intestine_Large
Fetal_Intestine_Small
Gastric
GM12878 INTERNATIONAL HAPMAP PROJECT - CEPH (PLATE I) [UTAH RESIDENTS WITH ANCESTRY FROM NORTHERN AND WESTERN EUROPE] CYTOCHROME P450, SUBFAMILY IIC, POLYPEPTIDE 19; CYP2C19 CEPH/UTAH PEDIGREE 1463
H1_BMP4_Derived_Mesendoderm_Cultured_Cells
H1_BMP4_Derived_Trophoblast_Cultured_Cells
H1_Cell_Line
H1_Derived_Mesenchymal_Stem_Cells
H1_Derived_Neuronal_Progenitor_Cultured_Cells
HELA Human cervix carcinoma established from the epitheloid cervix carcinoma of a 31-year-old black woman in 1951. Later diagnosis changed to adenocarcinoma, first aneuploid, continuously cultured human cell line.
HEPG2 Human hepatocellular carcinoma, established from the tumor tissue of a 15-year-old argentine boy with hepatocellular carcinoma in 1975.
hESC_Derived_CD184+_Endoderm_Cultured_Cells
hESC_Derived_CD56+_Ectoderm_Cultured_Cells
hESC_Derived_CD56+_Mesoderm_Cultured_Cells
HMEC
HSMM
HUES64_Cell_Line
HUVEC A convenient source of human endothelial cells are those that line the large vein in the umbilical cord which is usually discarded together with the placenta after childbirth. The cells can be removed as a fairly pure suspension by mild enzymatic treatment of the vein followed by some mechanical distraction and will grow relatively easily in culture, retaining their differentiated characteristics for several passages.
K562 Human chronic myeloid leukemia in blast crisis established from the pleural effusion of a 53-year-old woman with chronic myeloid leukemia (CML) in blast crisis in 1970.
Left_Ventricle The ventricles are the two lower chambers of the heart. The left ventricle is the chamber that receives blood from the left atrium and pumps it out under high pressure to the body via the aorta.
Lung One of the usually paired compound saccular thoracic organs that constitute the basic respiratory organ of air-breathing vertebrates.
Mobilized_CD34_Primary_Cells_Female
Neurosphere_Cultured_Cells_Cortex_Derived
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived
NHEK
NHLF
Ovary One of the typically paired essential female reproductive organs that produce eggs and in vertebrates female sex hormones.
Pancreas A large lobulated gland of vertebrates that secretes digestive enzymes and the hormones insulin and glucagon.
Pancreatic_Islets
Penis_Foreskin_Fibroblast_Primary_Cells_skin01
Penis_Foreskin_Fibroblast_Primary_Cells_skin02
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02
Penis_Foreskin_Keratinocyte_Primary_Cells_skin03
Penis_Foreskin_Melanocyte_Primary_Cells_skin01
Penis_Foreskin_Melanocyte_Primary_Cells_skin03
Peripheral_Blood_Mononuclear_Primary_Cells
Psoas_Muscle A powerful flexor of the thigh at the hip joint (psoas major) and a weak flexor of the trunk and lumbar spinal column (psoas minor). Psoas is derived from the Greek 'psoa', the plural meaning 'muscles of the loin'. It is a common site of infection manifesting as abscess (PSOAS ABSCESS). The psoas muscles and their fibers are also used frequently in experiments in muscle physiology.
Right_Atrium The right atrium receives deoxygenated blood from the body through the vena cava and pumps it into the right ventricle which then sends it to the lungs.
Right_Ventricle The lower right chamber of the heart that receives deoxygenated blood from the right atrium and pumps it under low pressure into the lungs via the pulmonary artery.
Sigmoid_Colon The S-shaped part of the colon which lies in the pelvis, extending from the pelvic brim to the third segment of the sacrum, and continuous above with the descending (or iliac) colon and below with the rectum.
Small_Intestine The part of the intestine that lies between the stomach and colon, consists of duodenum, jejunum, and ileum, secretes digestive enzymes, and is the chief site of the absorption of digested nutrients. The proximal portion of the intestine.
Spleen A highly vascular ductless organ that is located in the left abdominal region near the stomach or intestine of most vertebrates and is concerned with final destruction of red blood cells, filtration and storage of blood, and production of lymphocytes.
Thymus A glandular structure of largely lymphoid tissue that functions especially in the development of the body's immune system, is present in the young of most vertebrates typically in the upper anterior chest or at the base of the neck, and tends to atrophy in the adult.
Universal_Human_Reference