ProteomicsDB Cell Type and Tissue Protein Expression Profiles Dataset

Description protein expression profiles for tissues and cell types reprocessed from many proteomics datasets
Measurement protein expression by mass spectrometry
Association protein-cell type or tissue associations by differential expression of protein across tissues and cell types
Category proteomics
Resource Proteomics Database
Citation(s)
Last Updated
Stats
  1. 2776 genes
  2. 53 cell type or tissues
  3. 21921 gene-cell type or tissue associations

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cell type or tissue Gene Sets

53 sets of proteins with high or low expression in each cell type or tissue relative to other cell types and tissues from the ProteomicsDB Cell Type and Tissue Protein Expression Profiles dataset.

Gene Set Description
PC-3 cell Human prostate carcinoma cell line; established from the bone marrow metastasis isolated post-mortem from a 62-year-old Caucasian man with grade IV prostate cancer, poorly differentiated adenocarcinoma, after androgen suppression therapy; described to form tumors in nude mice, to grow in soft agar, and to be unresponsive to androgen treatment.
heart 1: A hollow muscular organ of vertebrate animals that by its rhythmic contraction acts as a force pump maintaining the circulation of the blood. 2: A structure in an invertebrate animal functionally analogous to the vertebrate heart.
Colo-205 cell Human Caucasian colon adenocarcinoma cell line. Isolated from ascitic fluid of a 70-year-old Caucasian male with carcinoma of the colon.
HMELonza cell or tissue derived from breast
GaMG cell Human glioblastoma cell line.
K-562 cell Human chronic myeloid leukemia in blast crisis established from the pleural effusion of a 53-year-old woman with chronic myeloid leukemia (CML) in blast crisis in 1970.
HMEpC cell Human Mammary Epithelial Cells (HMEpC) are derived from normal adult mammary glands.
A-549 cell Human lung carcinoma established from an explanted lung tumor which was removed from a 58-year-old Caucasian man in 1972; cells were described to induce tumors in athymic mice and to synthesize lecithin.
HeLa cell Human cervix carcinoma established from the epitheloid cervix carcinoma of a 31-year-old black woman in 1951. Later diagnosis changed to adenocarcinoma, first aneuploid, continuously cultured human cell line.
HCC-2218 disease: primary ductal carcinoma
MDA-MB-453 cell Human breast carcinoma cell line; established from an effusion of a 48-year-old woman with breast carcinoma in 1976.
colon The part of the large intestine that extends from the cecum to the rectum.
helper T-lymphocyte A T-cell that participates in an immune response by recognizing a foreign antigen and secreting lymphokines to activate T cell and B cell proliferation, that usually carries CD4 molecular markers on its cell surface, and that is reduced to 20 percent or less of normal numbers in AIDS.
cytotoxic T-lymphocyte Subset of T-lymphocytes (mostly CD8+) responsible for lysing target cells and for killing virus-infected cells.
lymphoblastoid cell line Human cell line from tissue infected with Epstein-Barr virus, resembling a lymphoblast.
SW-480 cell Human colon adenocarcinoma, established from the tumor of a 50-year-old Caucasian man with colon adenocarcinoma.
testis A typically paired male reproductive gland that produces sperm and that in most mammals is contained within the scrotum at sexual maturity.
HEK-293 cell Established from a human primary embryonal kidney transformed by adenovirus type 5.
MFM-223 cell Human breast carcinoma; established from the pleural effusion of a post-menopausal breast cancer patient without any prior treatment (tumor: widespread ductal mammary carcinoma T4 N2 M1 with histological grade III); cells were described to express androgen, estrogen and progesterone receptors.
SK-N-BE(2) cell The SK-N-BE(2) neuroblastoma cell line was established in November of 1972 from a bone marrow biopsy taken from child with disseminated neuroblastoma after repeated courses of chemotherapy and radiotherapy.
HCC-1143 disease: primary ductal carcinoma
non-small cell lung cancer cell line
HCC-202 disease: primary ductal carcinoma
Hep-G2 cell Human hepatocellular carcinoma, established from the tumor tissue of a 15-year-old argentine boy with hepatocellular carcinoma in 1975.
HeLa-S3 cell Human cervix carcinoma cell line is a subclone of its parent HELA derived in 1955.
MCF-10A cell Human mammary epithelial cell line.
JURKAT cell Human T cell leukemia, established from the peripheral blood of a 14-year-old boy with acute lymphoblastic leukemia (ALL) at first relapse in 1976; often this cell line is called JM (JURKAT and JM are derived from the same patient and are sister clones), occasionally JM may be a subclone with somewhat divergent features.
NFF cell or tissue derived from skin
HMT-3522 cell Non-tumorigenic immortalized human breast epithelial cell line, derived from a fibrocystic breast lesion.
PBMC cell line
retina The sensory membrane that lines the eye, is composed of several layers including one containing the rods and cones, and functions as the immediate instrument of vision by receiving the image formed by the lens and converting it into chemical and nervous signals which reach the brain by way of the optic nerve.
A-375 cell Skin malignant melanoma cell line; established from a 54 year old human female.
RKO cell Human colon carcinoma cell line. RKO is a poorly differentiated colon carcinoma cell line developed by Michael Brattain. The RKO cell line is the parental cell line (isogenic) of RKO-E6 and RKO-A545-1.
liver 1: A large very vascular glandular organ of vertebrates that secretes bile and causes important changes in many of the substances contained in the blood (as by converting sugars into glycogen which it stores up until required and by forming urea). 2: Any of various large compound glands associated with the digestive tract of invertebrate animals and probably concerned with the secretion of digestive enzymes.
prostate gland A firm partly muscular partly glandular body that is situated about the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
Mixed cell or tissue derived from mixed
rectum The terminal part of the intestine from the sigmoid flexure to the anus.
LNCaP cell Human prostate carcinoma, established from the left supraclavicular lymph node metastasis from a 50-year-old man with prostate carcinoma in 1977; cells were described to be androgen-sensitive.
pancreas A large lobulated gland of vertebrates that secretes digestive enzymes and the hormones insulin and glucagon.
placenta The vascular organ in mammals except monotremes and marsupials that unites the fetus to the maternal uterus and mediates its metabolic exchanges through a more or less intimate association of uterine mucosal with chorionic and usually allantoic tissues; also: an analogous organ in another animal.
HCC-1599 disease: primary ductal carcinoma
OVCAR-8/ADR cell Multidrug-resistant derivative of OVCAR-8.
MCF-7 cell Human breast adenocarcinoma, established from the pleural effusion of a 69-year-old caucasian woman with metastatic mammary carcinoma (after radio- and hormone therapy) in 1970. Cells were described of being positive for cytoplasmic estrogen receptors and having the capability to form domes.
HCC-1937 cell A primary ductal breast carcinoma cell line, initiated from a primary ductal carcinoma on October 13, 1995. The tumor was classified as TNM Stage IIB, grade 3.
natural killer cell A large granular lymphocyte capable of killing a tumor or microbial cell without prior exposure to the target cell and without having it presented with or marked by a histocompatibility antigen.
SW-620 cell Human, Caucasian, colon, adenocarcinoma cell line, established from the tissue of a 51-year-old Caucasian male.
M14 cell The human melanoma cell line M14 has been established from surgically removed melanoma metastases.
B-lymphocyte Any of the lymphocytes that have antibody molecules on the surface and comprise the antibody-secreting plasma cells when mature.
U2-OS cell Human osteosarcoma cell line.
lung One of the usually paired compound saccular thoracic organs that constitute the basic respiratory organ of air-breathing vertebrates.
ovary One of the typically paired essential female reproductive organs that produce eggs and in vertebrates female sex hormones.
colorectal cancer cell
HES-3 cell or tissue derived from stem_cells