LINCS Kinativ Kinase Inhibitor Bioactivity Profiles Dataset

Description percent inhibition of kinases by small molecules measured in cell lysates
Measurement chemical bioactivity
Association kinase-chemical bioactivity profile associations by percent inhibition of kinase by small molecule in cell line
Category physical interactions
Resource LINCS Kinativ
Last Updated
Stats
  1. 102 genes
  2. 23 chemical bioactivity profiles
  3. 149 gene-chemical bioactivity profile associations

Data Access

API
Script

Visualizations

  • Attribute Similarity

  • Dataset

  • Gene Similarity

chemical bioactivity profile Gene Sets

23 sets of kinases with high inhibition of kinase activity in chemical bioactivity profiles from the Kinativ Kinase Inhibitor Bioactivity Profiles dataset.

Gene Set Description
BX795_NGP kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
CH5424802_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
DCC-2036_Ramos (RA 1) kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
HG-6-64-01_A-375 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
Ibrutinib_Ramos (RA 1) kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
JWE-035_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
NPK76-II-72-1_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
NPK76-II-72-1_PC-3 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
NVP-BHG712_PC-3 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
OTSSP167_MDA-MB-468 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
QL-X-138_BCWM.1 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
Torin1_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
Torin2_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD-12_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD-12_PC-3 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD11-50_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD11-85h_PC-3 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD16-144_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD16-144_PC-3 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD8-85_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD8-85_PC-3 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD8-92_HeLa kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]
XMD8-92_PC-3 kinase inhibitor bioactivity profile identified as [chemical name]_[cell line name]