HPA Tissue Gene Expression Profiles Dataset

Description mRNA expression profiles for tissues
Measurement gene expression by RNA-seq
Association gene-tissue associations by differential expression of gene across tissues
Category transcriptomics
Resource Human Protein Atlas
Last Updated
  1. 17423 genes
  2. 31 tissues
  3. 81082 gene-tissue associations

Data Access



  • Attribute Similarity

  • Dataset

  • Gene Similarity

tissue Gene Sets

31 sets of genes with high or low expression in each tissue relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.

Gene Set Description
adipose tissue Connective tissue in which fat is stored and which has the cells distended by droplets of fat.
adrenal gland Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine.
appendix A narrow blind tube usually about three or four inches (7.6 to 10.2 centimeters) long that extends from the cecum in the lower right-hand part of the abdomen, has much lymphoid wall tissue, normally communicates with the cavity of the cecum, and represents an atrophied terminal part of the cecum.
bone marrow The soft, fatty, vascular tissue that fills most bone cavities and is the source of red blood cells and many white blood cells.
brain 1: The portion of the vertebrate central nervous system that constitutes the organ of thought and neural coordination, includes all the higher nervous centers receiving stimuli from the sense organs and interpreting and correlating them to formulate the motor impulses, is made up of neurons and supporting and nutritive structures, is enclosed within the skull, and is continuous with the spinal cord through the foramen magnum. Also named encephalon. 2: A nervous center in invertebrates comparable in position and function to the vertebrate brain.
colon The part of the large intestine that extends from the cecum to the rectum.
duodenum The first part of the small intestine extending from the pylorus to the jejunum.
endometrium The mucous membrane lining the uterus.
esophagus A muscular tube that in humans is about nine inches (23 centimeters) long and passes from the pharynx down the neck between the trachea and the spinal column and behind the left bronchus where it pierces the diaphragm slightly to the left of the middle line and joins the cardiac end of the stomach.
fallopian tube Either of a pair of slender ducts through which ova pass from the ovaries to the uterus in the female reproductive system of humans and higher mammals.
gallbladder A small, pear-shaped muscular sac, located under the right lobe of the liver, in which bile secreted by the liver is stored until needed by the body for digestion.
heart muscle The principal muscle tissue of the vertebrate heart made up of striated fibers that appear to be separated from each other under the electron microscope but that function in long-term rhythmic contraction as if in protoplasmic continuity.
kidney 1: One of a pair of vertebrate organs situated in the body cavity near the spinal column that excrete waste products of metabolism, in humans are bean-shaped organs about 4 1/2 inches (11 1/2 centimeters) long lying behind the peritoneum in a mass of fatty tissue, and consist chiefly of nephrons by which urine is secreted, collected, and discharged into a main cavity whence it is conveyed by the ureter to the bladder. 2: Any of various excretory organs of invertebrate animals.
liver 1: A large very vascular glandular organ of vertebrates that secretes bile and causes important changes in many of the substances contained in the blood (as by converting sugars into glycogen which it stores up until required and by forming urea). 2: Any of various large compound glands associated with the digestive tract of invertebrate animals and probably concerned with the secretion of digestive enzymes.
lung One of the usually paired compound saccular thoracic organs that constitute the basic respiratory organ of air-breathing vertebrates.
lymph node Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph.
ovary One of the typically paired essential female reproductive organs that produce eggs and in vertebrates female sex hormones.
pancreas A large lobulated gland of vertebrates that secretes digestive enzymes and the hormones insulin and glucagon.
placenta The vascular organ in mammals except monotremes and marsupials that unites the fetus to the maternal uterus and mediates its metabolic exchanges through a more or less intimate association of uterine mucosal with chorionic and usually allantoic tissues; also: an analogous organ in another animal.
prostate A firm partly muscular partly glandular body that is situated about the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
rectum The terminal part of the intestine from the sigmoid flexure to the anus.
salivary gland The glands of the oral cavity whose combined secretion constitutes the saliva.
skeletal muscle A usually voluntary muscle made up of elongated, multinucleated, transversely striated muscle fibers, having principally bony attachments.
skin The integument of an animal (as a fur-bearing mammal or a bird) separated from the body usually with its hair or feathers.
small intestine The part of the intestine that lies between the stomach and colon, consists of duodenum, jejunum, and ileum, secretes digestive enzymes, and is the chief site of the absorption of digested nutrients. The proximal portion of the intestine.
smooth muscle Muscle tissue that lacks cross striations, that is made up of elongated spindle-shaped cells having a central nucleus, and that is found in vertebrate visceral structures (as the stomach and bladder) as thin sheets performing functions not subject to conscious control by the mind and in all or most of the musculature of invertebrates other than arthropods.
spleen A highly vascular ductless organ that is located in the left abdominal region near the stomach or intestine of most vertebrates and is concerned with final destruction of red blood cells, filtration and storage of blood, and production of lymphocytes.
stomach A dilatation of the alimentary canal of a vertebrate communicating anteriorly with the esophagus and posteriorly with the duodenum.
thyroid gland A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin.
tonsil The human palatine tonsils and the nasopharyngeal tonsil are lymphoepithelial tissues located in strategic areas of the oropharynx and nasopharynx, although most commonly, the term tonsils refers to the palatine tonsils that can be seen in the back of the throat.
urinary bladder A membranous sac in many vertebrates that serves for the temporary retention of urine and discharges by the urethra.